Search Results - "Amaral, Ana Claudia F"
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Leishmania infantum arginase: biochemical characterization and inhibition by naturally occurring phenolic substances
Published in Journal of enzyme inhibition and medicinal chemistry (01-01-2019)“…Inhibition of Leishmania arginase leads to a decrease in parasite growth and infectivity and thus represents an attractive therapeutic strategy. We evaluated…”
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Anti-'Leishmania amazonensis' activity, cytotoxic features, and chemical profile of 'Allium sativum' (garlic) essential oil
Published in Tropical medicine and infectious disease (21-07-2023)“…Human tegumentary leishmaniasis (HTL) is a serious tropical disease caused by 'Leishmania amazonensis'. Developing new leishmanicidal agents can help overcome…”
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Delving into the Mechanisms of Sponge-Associated Enterobacter against Staphylococcal Biofilms
Published in Molecules (Basel, Switzerland) (19-06-2023)“…Staphylococci are one of the most common causes of biofilm-related infections. Such infections are hard to treat with conventional antimicrobials, which often…”
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Umbelliferone esters with antibacterial activity produced by lipase-mediated biocatalytic pathway
Published in Biotechnology letters (01-02-2021)“…Objective The present report describes the enzymatic acylation of umbelliferone with different vinyl esters as acyl donors biocatalyzed by the commercial…”
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Rutin derivatives obtained by transesterification reactions catalyzed by Novozym 435: Antioxidant properties and absence of toxicity in mammalian cells
Published in PloS one (19-09-2018)“…Flavonoids are one of the most important and diversified phenolic groups among products of natural origin. An important property of this metabolite class is…”
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Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential
Published in TheScientificWorld (2020)“…Herbal medicines containing Passiflora species have been widely used to treat anxiety since ancient times. The species Passiflora incarnata L. is included in…”
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Trimethylamine N-Oxide From Gut Microbiota in Chronic Kidney Disease Patients: Focus on Diet
Published in Journal of renal nutrition (01-11-2015)“…Low-protein diet is the recommended nutritional intervention for nondialysis chronic kidney disease (CKD) patients because excess protein intake can damage…”
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Natural Products: Insights into Leishmaniasis Inflammatory Response
Published in Mediators of Inflammation (01-01-2015)“…Leishmaniasis is a vector-borne disease that affects several populations worldwide, against which there are no vaccines available and the chemotherapy is…”
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Piper capitarianum essential oil: a promising insecticidal agent for the management of Aedes aegypti and Aedes albopictus
Published in Environmental science and pollution research international (01-02-2021)“…Mosquitoes are responsible for serious public health problems worldwide, and as such, Aedes aegypti and Aedes albopictus are important vectors in the…”
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Evaluation of the chemical composition and antioxidant activity of extracts and fractions of Ocotea notata (Ness) Mez (Lauraceae)
Published in Natural product research (17-10-2020)“…The specie Ocotea notata (Nees & Mart). Mez is a tree with 5 meters high, that can be found in restinga regions in the Brazilian coast. This study describes a…”
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Alpinia Essential Oils and Their Major Components against Rhodnius nasutus, a Vector of Chagas Disease
Published in TheScientificWorld (2018)“…Species of the genus Alpinia are widely used by the population and have many described biological activities, including activity against insects. In this…”
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Cytotoxicity and anti-Leishmania amazonensis activity of Citrus sinensis leaf extracts
Published in Pharmaceutical biology (2017)“…Context: Leishmania amazonensis is the main agent of diffuse cutaneous leishmaniasis, a disease characterized by lesional polymorphism and the commitment of…”
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pyrimidine-β-carboline and other alkaloids from Annona foetida with antileishmanial activity
Published in Journal of natural products (Washington, D.C.) (01-02-2006)“…Bioassay-guided fractionation of the bark extract of Annona foetida afforded a new antileishmanial pyrimidine-beta-carboline alkaloid, N-hydroxyannomontine…”
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Ethyl Acetate Fraction and Isolated Phenolics Derivatives from Mandevilla moricandiana Identified by UHPLC-DAD-ESI-MSn with Pharmacological Potential for the Improvement of Obesity-Induced Endothelial Dysfunction
Published in Pharmaceutics (29-07-2021)“…Endothelial dysfunction in obesity plays a key role in the development of cardiovascular diseases, and it is characterized by increased vascular tonus and…”
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Chemical Profile and Hematoprotective Activity of Artisanal Jabuticaba (Plinia jabuticaba) Wine and Derived Extracts
Published in Fermentation (Basel) (01-02-2023)“…The alcoholic fermentation of jabuticaba berries (Plinia spp.) originates from a beverage with an intense taste and aroma, popularly known as jabuticaba wine…”
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A review of antimalarial plants used in traditional medicine in communities in Portuguese-speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola
Published in Memórias do Instituto Oswaldo Cruz (01-08-2011)“…The isolation of bioactive compounds from medicinal plants, based on traditional use or ethnomedical data, is a highly promising potential approach for…”
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PLGA nanoparticles optimized by Box-Behnken for efficient encapsulation of therapeutic Cymbopogon citratus essential oil
Published in Colloids and surfaces, B, Biointerfaces (01-09-2019)“…[Display omitted] •Box-Behnken design allows establishing the optimal experimental conditions.•Only citral was incorporated into the optimized PLGA…”
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Antileishmanial Screening, Cytotoxicity, and Chemical Composition of Essential Oils: A Special Focus on Piper callosum Essential Oil
Published in Chemistry & biodiversity (01-02-2023)“…Leishmania amazonensis is the etiological agent of tegumentary leishmaniasis, a disease characterized by the emergence of cutaneous and mucocutaneous ulcerated…”
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Enantioselectivity of pinene against Leishmania amazonensis
Published in Medicinal chemistry research (2024)“…Pinene is a major monoterpene described in various plant essential oils. It has two isomers, α- and β-pinene, that differ in the position of their double bond…”
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Development of Nanoemulsions to Enhance the Antileishmanial Activity of Copaifera paupera Oleoresins
Published in BioMed research international (01-01-2018)“…Based on the ethnopharmacological evidences about the antileishmanial activity of Copaifera spp. oleoresins, the effects of crude extracts and fractions of…”
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