Search Results - "Amann, Kurt J"
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The Structural Basis of Actin Filament Branching by the Arp2/3 Complex
Published in The Journal of cell biology (10-03-2008)“…The actin-related protein 2/3 (Arp2/3) complex mediates the formation of branched actin filaments at the leading edge of motile cells and in the comet tails…”
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Direct Real-Time Observation of Actin Filament Branching Mediated by Arp2/3 Complex Using Total Internal Reflection Fluorescence Microscopy
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2001)“…Existing methods for studying actin filament dynamics have allowed analysis only of bulk samples or individual filaments after treatment with the drug…”
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Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins
Published in Nature (London) (27-04-2000)“…Most nucleated cells crawl about by extending a pseudopod that is driven by the polymerization of actin filaments in the cytoplasm behind the leading edge of…”
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The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments
Published in Nature cell biology (01-03-2001)“…Regulated assembly of actin-filament networks provides the mechanical force that pushes forward the leading edge of motile eukaryotic cells and intracellular…”
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EPLIN Regulates Actin Dynamics by Cross-Linking and Stabilizing Filaments
Published in The Journal of cell biology (03-02-2003)“…Epithelial protein lost in neoplasm (EPLIN) is a cytoskeleton-associated protein encoded by a gene that is down-regulated in transformed cells. EPLIN increases…”
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Structure of Arp2/3 Complex in Its Activated State and in Actin Filament Branch Junctions
Published in Science (American Association for the Advancement of Science) (28-09-2001)“…The seven-subunit Arp2/3 complex choreographs the formation of branched actin networks at the leading edge of migrating cells. When activated by…”
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Polymerization Properties of the Thermotoga maritima Actin MreB: Roles of Temperature, Nucleotides, and Ions
Published in Biochemistry (Easton) (15-01-2008)“…MreB is a bacterial orthologue of actin that affects cell shape, polarity, and chromosome segregation. Although a significant body of work has explored its…”
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Proteolysis of cortactin by calpain regulates membrane protrusion during cell migration
Published in Molecular biology of the cell (01-01-2006)“…Calpain 2 regulates membrane protrusion during cell migration. However, relevant substrates that mediate the effects of calpain on protrusion have not been…”
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A Cluster of Basic Repeats in the Dystrophin Rod Domain Binds F-actin through an Electrostatic Interaction
Published in The Journal of biological chemistry (23-10-1998)“…The dystrophin rod domain is composed of 24 spectrin-like repeats and was thought to act mainly as a flexible spacer between the amino-terminal actin binding…”
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A New Model for the Interaction of Dystrophin with F-Actin
Published in The Journal of cell biology (01-11-1996)“…The F-actin binding and cross-linking properties of skeletal muscle dystrophin-glycoprotein complex were examined using high and low speed cosedimentation…”
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Assembly properties of the Bacillus subtilis actin, MreB
Published in Cell motility and the cytoskeleton (01-02-2009)“…The bacterial actin MreB has been implicated in a variety of cellular roles including cell shape determination, cell wall synthesis, chromosome condensation…”
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Utrophin Lacks the Rod Domain Actin Binding Activity of Dystrophin
Published in The Journal of biological chemistry (10-12-1999)“…We previously identified a cluster of basic spectrin-like repeats in the dystrophin rod domain that binds F-actin through electrostatic interactions (Amann, K…”
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13
Polymerization Properties of the Thermotoga maritima Actin MreB: Roles of Temperature, Nucleotides, and Ions
Published in Biochemistry (Easton) (01-01-2008)“…MreB is a bacterial orthologue of actin that affects cell shape, polarity, and chromosome segregation. Although a significant body of work has explored its…”
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14
POLYMERIZATION PROPERTIES OF THE T. MARITIMA ACTIN, MreB: ROLES OF TEMPERATURE, NUCLEOTIDES AND IONS
Published in Biochemistry (Easton) (21-12-2007)“…MreB is a bacterial ortholog of actin that affects cell shape, polarity and chromosome segregation. Although a significant body of work has explored its…”
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15
Proteolysis of Cortactin by Calpain Regulates Membrane Protrusion during Cell MigrationD
Published in Molecular biology of the cell (01-01-2006)“…Calpain 2 regulates membrane protrusion during cell migration. However, relevant substrates that mediate the effects of calpain on protrusion have not been…”
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Cellular regulation of actin network assembly
Published in Current biology (19-10-2000)Get full text
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Dystrophin binding to nonmuscle actin
Published in Cell motility and the cytoskeleton (1998)“…We purified actin from bovine brain by DNase I affinity chromatography in order to compare the binding of dystrophin to muscle actin with its binding to…”
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