Search Results - "Amanda Duvall, E"

Final outcomes analysis of the cell product SQZ‐PBMC‐HPV Phase 1 trial in incurable HPV16+ solid tumors shows improved overall survival in patients with increased CD8+ T cell tumor infiltration by Weaver, Alice N., Iams, Wade T., Park, Jong Chul, Mita, Monica, Holtick, Udo, Gordon, Michael S., Rodabaugh, Kerry J., Dhani, Neesha, Neupane, Prakash, Taylor, Matthew, Amanda Duvall, E., Jennings, Julia, Miselis, Nathan R., Loughhead, Scott, Warren, Marshelle S., Bernstein, Howard, Klussmann, Jens P., Baranda, Joaquina, Jimeno, Antonio

“…Cancer vaccines strive to induce robust, antigen‐targeted, T‐cell‐mediated immune responses but have struggled to produce meaningful regression in solid…”
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594 SQZ-PBMC-HPV-101: Increased overall survival in a subset of patients with recurrent, locally advanced, or metastatic HPV16+ tumors treated with cell-based vaccine, SQZ-PBMC-HPV by Jimeno, Antonio, Iams, Wade T, Park, Jong Chul, MitaSc, Monica, Holtick, Udo, Gordon, Michael S, Rodabaugh, Kerry J, Dhani, Neesha, Taylor, Matthew H, Amanda Duvall, E, Jennings, Julia, Miselis, Nathan, Loughhead, Scott, Warren, Marshelle S, Bernstein, Howard, Baranda, Joaquina

“…BackgroundCancer vaccines aim to generate antigen-specific CD8+ T cell responses. However, their efficacy has been hampered by inefficient targeting of…”
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