Search Results - "Amador, Ariadna"
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1
Quantifying Drosophila food intake: comparative analysis of current methodology
Published in Nature methods (01-05-2014)“…This Analysis compares four commonly used assays to measure food intake in flies and identifies radioisotope-labeling and the capillary feeder (CAFE) as the…”
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Journal Article -
2
Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle
Published in PloS one (03-05-2018)“…The nuclear receptors REV-ERBα and REV-ERBβ have been demonstrated to be core members of the circadian clock and participate in the regulation of a diverse set…”
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Journal Article -
3
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors
Published in Neurobiology of disease (01-02-2020)“…ARFGEF1 encodes a guanine exchange factor involved in intracellular vesicle trafficking, and is a candidate gene for childhood genetic epilepsies. To model…”
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4
Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation
Published in PloS one (07-09-2016)“…The circadian clock maintains appropriate timing for a wide range of behaviors and physiological processes. Circadian behaviors such as sleep and wakefulness…”
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Journal Article -
5
Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
Published in PloS one (10-03-2016)“…The nuclear receptors REV-ERBα and REV-ERBβ are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various metabolic…”
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Journal Article -
6
Correction: Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
Published in PloS one (19-05-2016)“…[This corrects the article DOI: 10.1371/journal.pone.0151014.]…”
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7
Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice
Published in Brain (London, England : 1878) (01-07-2020)“…NMDA receptors play crucial roles in excitatory synaptic transmission. Rare variants in GRIN2A encoding the GluN2A subunit are associated with a spectrum of…”
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8
Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour
Published in Nature communications (23-12-2014)“…Synthetic drug-like molecules that directly modulate the activity of key clock proteins offer the potential to directly modulate the endogenous circadian…”
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9
REV-ERBβ is required to maintain normal wakefulness and the wake-inducing effect of dual REV-ERB agonist SR9009
Published in Biochemical pharmacology (01-04-2018)“…[Display omitted] Circadian signaling regulates and synchronizes physiological and behavioral processes, such as feeding, metabolism, and sleep cycles. The…”
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10
Distinct roles for REV-ERB[alpha] and REV-ERB[beta] in oxidative capacity and mitochondrial biogenesis in skeletal muscle
Published in PloS one (03-05-2018)“…The nuclear receptors REV-ERB[alpha] and REV-ERB[beta] have been demonstrated to be core members of the circadian clock and participate in the regulation of a…”
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Journal Article -
11
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA A receptors
Published in Neurobiology of disease (01-02-2020)“…ARFGEF1 encodes a guanine exchange factor involved in intracellular vesicle trafficking, and is a candidate gene for childhood genetic epilepsies. To model…”
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Journal Article -
12
The Regulation of Sleep and Wakefulness by the REV_ERBs
Published 01-01-2015“…Our circadian clock coordinates the 24-hour rhythmicity of various physiological processes, including sleep and wake behaviors, in order to maintain…”
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Dissertation -
13
Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression: e0151014
Published in PloS one (01-03-2016)“…The nuclear receptors REV-ERB alpha and REV-ERB[Beta] are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various…”
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Journal Article