Search Results - "Amado, Patrícia S. M"

Synthesis, Structure and Antileishmanial Evaluation of Endoperoxide–Pyrazole Hybrids by Amado, Patrícia S. M, Costa, Inês C. C, Paixão, José A, Mendes, Ricardo F, Cortes, Sofia, Cristiano, Maria L. S

“…Leishmaniases are among the most impacting neglected tropical diseases. In attempts to repurpose antimalarial drugs or candidates, it was found that selected…”
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Bond-Breaking/Bond-Forming Reactions by Vibrational Excitation: Infrared-Induced Bidirectional Tautomerization of Matrix-Isolated Thiotropolone by Nunes, Cláudio M, Pereira, Nelson A. M, Reva, Igor, Amado, Patrícia S. M, Cristiano, Maria L. S, Fausto, Rui

“…Infrared vibrational excitation is a promising approach for gaining exceptional control of chemical reactions, in ways that cannot be attained via thermal or…”
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Synthesis of Non-symmetrical Dispiro-1,2,4,5-Tetraoxanes and Dispiro-1,2,4-Trioxanes Catalyzed by Silica Sulfuric Acid by Amado, Patrícia S. M, Frija, Luís M. T, Coelho, Jaime A. S, O’Neill, Paul M, Cristiano, Maria L. S

“…A novel protocol for the preparation of non-symmetrical 1,2,4,5-tetraoxanes and 1,2,4-trioxanes, promoted by the heterogeneous silica sulfuric acid (SSA)…”
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The Potential of Chitosan-Based Composites for Adsorption of Diarrheic Shellfish Toxins by Leal, Joana F, Amado, Patrícia S M, Lourenço, João P, Cristiano, Maria L S

“…Okadaic acid (OA) is one of the most potent marine biotoxins, causing diarrheal shellfish poisoning (DSP). The proliferation of microalgae that produce OA and…”
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Photoinduced Reactivity in a Dispiro-1,2,4-trioxolane: Adamantane Ring Expansion and First Direct Observation of the Long-Lived Triplet Diradical Intermediates by Brás, Elisa M, Cabral, Lília I. L, Amado, Patrícia S. M, Abe, Manabu, Fausto, Rui, Cristiano, Maria L. S

“…Dispiro-1,2,4-trioxolane, 1, an ozonide with efficient and broad antiparasitic activity, was synthesized and investigated using matrix isolation FTIR and EPR…”
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Recent Advances of DprE1 Inhibitors against Mycobacterium tuberculosis: Computational Analysis of Physicochemical and ADMET Properties by Amado, Patrícia S. M., Woodley, Christopher, Cristiano, Maria L. S., O’Neill, Paul M.

“…Decaprenylphosphoryl-β-d-ribose 2′-epimerase (DprE1) is a critical flavoenzyme in Mycobacterium tuberculosis, catalyzing a vital step in the production of…”
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Cation-Exchange Resin Applied to Paralytic Shellfish Toxins Depuration from Bivalves Exposed to Gymnodinium catenatum by Leal, Joana F, Bombo, Gabriel, Amado, Patrícia S M, Pereira, Hugo, Cristiano, Maria L S

“…The accumulation of marine biotoxins in shellfish and their consumption causes serious food safety problems, threatening human health and compromising the…”
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Artemisinin inspired synthetic endoperoxide drug candidates: Design, synthesis, and mechanism of action studies by Woodley, Christopher M., Amado, Patrícia S. M., Cristiano, Maria L. S., O'Neill, Paul M.

“…Artemisinin combination therapies (ACTs) have been used as the first‐line treatments against Plasmodium falciparum malaria for decades. Recent advances in…”
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Molecular and Crystal Structure, Spectroscopy, and Photochemistry of a Dispiro Compound Bearing the Tetraoxane Pharmacophore by Amado, Patrícia S. M., Lopes, Susy, Brás, Elisa M., Paixão, José A., Takano, Ma‐aya, Abe, Manabu, Fausto, Rui, Cristiano, Maria L. S.

“…The molecular structure and photochemistry of dispiro[cyclohexane‐1,3′‐[1,2,4,5]tetraoxane‐6′,2′′‐tricyclo[3.3.1.13,7]decan]‐4‐one (TX), an antiparasitic…”
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Unravelling the Structure of Peroxides with Antiparasitic Activity: The Relative Impact of a Trioxolane or a Tetraoxane Pharmacophore on the Overall Molecular Structure by Amado, Patrícia S. M., Jesus, A. J. Lopes, Paixão, José A., Fausto, Rui, Cristiano, Maria L. S.

“…Plasmodium falciparum artemisinin‐resistance boosted the quest for novel plasmodial “fast killers,” uncovering antimalarial candidates OZ439 and E209, whose…”
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Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani by Cabral, Lília I L, Pomel, Sébastien, Cojean, Sandrine, Amado, Patrícia S M, Loiseau, Philippe M, Cristiano, Maria L S

“…A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of . All 15 tested tetraoxanes…”
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1,2,4-Trioxolane and 1,2,4,5-Tetraoxane Endoperoxides against Old-World Leishmania Parasites: In Vitro Activity and Mode of Action by Mendes, Andreia, Armada, Ana, Cabral, Lília I L, Amado, Patrícia S M, Campino, Lenea, Cristiano, Maria L S, Cortes, Sofia

“…Leishmaniasis remains one of the ten Neglected Tropical Diseases with significant morbidity and mortality in humans. Current treatment of visceral…”
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On the Development of Selective Chelators for Cadmium: Synthesis, Structure and Chelating Properties of 3-((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)amino)benzo[ d ]isothiazole 1,1-dioxide, a Novel Thiadiazolyl Saccharinate by Leal, Joana F, Guerreiro, Bruno, Amado, Patrícia S M, Fernandes, André L, Barreira, Luísa, Paixão, José A, Cristiano, Maria L S

“…Aquatic contamination by heavy metals is a major concern for the serious negative consequences it has for plants, animals, and humans. Among the most toxic…”
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Cation-Exchange Resin Applied to Paralytic Shellfish Toxins Depuration from Bivalves Exposed to IGymnodinium catenatum/I by Leal, Joana F, Bombo, Gabriel, Amado, Patrícia S. M, Pereira, Hugo, Cristiano, Maria L. S

“…The accumulation of marine biotoxins in shellfish and their consumption causes serious food safety problems, threatening human health and compromising the…”
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