Search Results - "Amado, Daniela"
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CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant Candida glabrata
Published in PloS one (18-03-2022)“…Invasive fungal infections, which kill more than 1.6 million patients each year worldwide, are difficult to treat due to the limited number of antifungal drugs…”
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2
Clipped histone H3 is integrated into nucleosomes of DNA replication genes in the human malaria parasite Plasmodium falciparum
Published in EMBO reports (01-04-2019)“…Post‐translational modifications of histone H3 N‐terminal tails are key epigenetic regulators of virulence gene expression and sexual commitment in the human…”
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3
A new nucleocytoplasmic RhoGAP protein contributes to control the pathogenicity of Entamoeba histolytica by regulating EhRacC and EhRacD activity
Published in Cellular microbiology (01-11-2016)“…Summary Small GTPases are signalling molecules that regulate important cellular processes. GTPases are deactivated by GTPase‐activating proteins (GAPs). While…”
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4
Development and Validation of an in-House Library of Colombian Candida auris Strains with MALDI-TOF MS to Improve Yeast Identification
Published in Journal of fungi (Basel) (27-05-2020)“…Background: is characterized for having a high genetic variability among species. MALDI-TOF MS library contains spectra from only three strains of , which…”
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Extracellular Vesicles and Their Impact on the Biology of Protozoan Parasites
Published in Tropical medicine and infectious disease (01-09-2023)“…Extracellular vesicles (EVs) are lipid-membrane-bound structures produced naturally by all cells and have a variety of functions. EVs act as vehicles for…”
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The NAD + Responsive Transcription Factor ERM-BP Functions Downstream of Cellular Aggregation and Is an Early Regulator of Development and Heat Shock Response in Entamoeba
Published in Frontiers in cellular and infection microbiology (17-07-2020)“…is a protozoan parasite and a major cause of dysentery and diarrheal disease in developing countries. Disease transmission from one host to another occurs via…”
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Síndrome de Mayer-Rokitansky-Küster-Hauser: estigma, corpo, mídia e bioética
Published in RECIIS, revista electrônica de comunicação, informação & inovação em saúde (28-06-2019)“…O objetivo do estudo que fundamenta este artigo foi identificar e compreender a construção do estigma social relacionado à síndrome de…”
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8
Equidade em situações-limite: acesso ao tratamento para pessoas com hemofilia
Published in Revista bioética (01-03-2022)“…Resumo Hemofilia é uma condição hematológica rara e seu tratamento é alvo de inovação terapêutica. No encontro entre necessidades do paciente, condutas do…”
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Comprehensive bioinformatic analysis reveals oncogenic role of H2A.Z isoforms in cervical cancer progression
Published in Iranian journal of basic medical sciences (01-11-2021)“…Cervical cancer ranks as the fourth most common neoplasia in women worldwide in which epigenetic alterations play an important role. Several studies have…”
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Identification of two transcription factors that work coordinately to regulate early development in Entamoeba
Published in mBio (14-11-2024)“…The protozoan parasite Entamoeba has a life cycle that switches between infective cysts and invasive trophozoites. Encystation, a crucial process in parasite…”
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In Silico Identification and Characterization of circRNAs as Potential Virulence-Related miRNA/siRNA Sponges from Entamoeba histolytica and Encystment-Related circRNAs from Entamoeba invadens
Published in Non-coding RNA (26-09-2022)“…Ubiquitous eukaryotic non-coding circular RNAs regulate transcription and translation. We have reported full-length intronic circular RNAs (flicRNAs) in…”
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Lanostanoid triterpenes from the fungus Rigidoporus microporus
Published in Natural product research (02-11-2021)“…Five new lanostanoid triterpenes were isolated from the extract of R. microporus. Three of the metabolites (1-3) present a Δ 8,9 skeleton with an uncommon keto…”
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Entamoeba stage conversion: progress and new insights
Published in Current opinion in microbiology (01-12-2020)“…Entamoeba histolytica, an anaerobic protozoan, is an important global health problem. This parasite has a biphasic life cycle consisting of a dormant cyst…”
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Impact of calmodulin inhibition by fluphenazine on susceptibility, biofilm formation and pathogenicity of caspofungin-resistant Candida glabrata
Published in Journal of antimicrobial chemotherapy (01-05-2020)“…Abstract Background In recent decades, Candida glabrata has emerged as a frequent cause of life-threatening fungal infection. In C. glabrata, echinocandin…”
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15
CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1
Published in PloS one (18-03-2022)“…Invasive fungal infections, which kill more than 1.6 million patients each year worldwide, are difficult to treat due to the limited number of antifungal drugs…”
Get full text
Journal Article -
16
Folding Kinetics and Volume Variation of the β‑Hairpin Peptide Chignolin upon Ultrafast pH-Jumps
Published in The journal of physical chemistry. B (23-05-2024)“…In-depth characterization of fundamental folding steps of small model peptides is crucial for a better understanding of the folding mechanisms of more complex…”
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17
PfAP2Tel, harbouring a non‐canonical DNA‐binding AP2 domain, binds to Plasmodium falciparum telomeres
Published in Cellular microbiology (01-09-2017)“…Summary The telomeres of the malaria parasite Plasmodium falciparum are essential not only for chromosome end maintenance during blood stage development in…”
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18
Equity in limit situations: access to treatment for people with hemophilia
Published in Revista bioética (01-03-2022)“…Abstract Hemophilia is a rare hematological condition and its treatment is the target of therapeutic innovation. In the meeting between patient needs,…”
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A class I histone deacetylase is implicated in the encystation of Entamoeba invadens
Published in International journal for parasitology (01-10-2020)“…[Display omitted] •Levels of histone H4 acetylation are regulated in a stage‐specific manner.•Histone hyperacetylation negatively affects the encystation of…”
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Violência obstétrica e bioética
Published in Revista Latinoamericana de Bioética (01-06-2023)“…Esta pesquisa traz uma abordagem qualitativa exploratória, com objetivo de identificar a percepção dos estudantes da área da saúde sobre a violência obstétrica…”
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