Search Results - "Amadeu de Oliveira, Flávia"
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The cytotoxic effect of TiF4 and NaF on fibroblasts is influenced by the experimental model, fluoride concentration and exposure time
Published in PloS one (14-06-2017)“…Titanium tetrafluoride (TiF4) has shown promising effect in preventing tooth lesions. Therefore, we compared the cytotoxicity of TiF4 with sodium fluoride…”
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In vitro and in vivo assessment of CaP materials for bone regenerative therapy. The role of multinucleated giant cells/osteoclasts in bone regeneration
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-01-2020)“…In this work, bone formation/remodeling/maturation was correlated with the presence of multinucleated giant cells (MGCs)/osteoclasts (tartrate‐resistant acid…”
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3
Low level laser therapy modulates viability, alkaline phosphatase and matrix metalloproteinase-2 activities of osteoblasts
Published in Journal of photochemistry and photobiology. B, Biology (01-04-2017)“…Low level laser therapy (LLLT) has been shown to stimulate bone cell metabolism but their impact on the matrix metalloproteinase (MMP) expression and activity…”
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4
Surface roughness of titanium disks influences the adhesion, proliferation and differentiation of osteogenic properties derived from human
Published in International journal of implant dentistry (25-08-2020)“…Purpose The aim of this study was to investigate the response of osteogenic cell lineage and gingival fibroblastic cells to different surface treatments of…”
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Effects of Qualea grandiflora Extract on the Expression of MMP-14 and HIF-1α in Cultured Fibroblasts and Preosteoblasts
Published in Brazilian Archives of Biology and Technology (01-01-2021)“…Abstract Background: Qualea grandiflora (QG) (Vochysiaceae), also known as "pau-ferro", "pau-terra" or "pau-de-tucano", is a very common deciduous tree in the…”
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The Multifarious Functions of Leukotrienes in Bone Metabolism
Published in Journal of bone and mineral research (01-08-2023)“…ABSTRACT Leukotrienes (LTs) are derived from arachidonic acid metabolism by the 5‐lipoxygenase (5‐LO) enzyme. The production of LTs is stimulated in the…”
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The effect of fluoride on the structure, function, and proteome of intestinal epithelia
Published in Environmental toxicology (01-01-2018)“…Fluoride exposure is widespread, with drinking water commonly containing natural and artificially added sources of the ion. Ingested fluoride undergoes…”
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Dentoalveolar Alterations in an Adenine‐Induced Chronic Kidney Disease Mouse Model
Published in Journal of bone and mineral research (01-08-2023)“…ABSTRACT Chronic kidney disease (CKD) is characterized by kidney damage and loss of renal function. CKD mineral and bone disorder (CKD–MBD) describes the…”
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TiF4 and NaF varnishes induce low levels of apoptosis in murine and human fibroblasts through mitochondrial Bcl-2 family and death receptor signalling
Published in Archives of oral biology (01-01-2019)“…•TiF4 and NaF varnishes have similar apoptosis effects on NIH/3T3 and HGF.•HGF is more susceptible to the effect of the fluoride varnishes than NIH/3T3.•TiF4…”
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Laser and light-emitting diode effects on pre-osteoblast growth and differentiation
Published in Lasers in medical science (2014)“…The acceleration of bone regeneration by low-intensity laser irradiation may hold potential benefits in clinical therapy in orthopedics and dentistry. The…”
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"Aroeira" (Myracrodruon urundeuva) methanol extract: the relationship between chemical compounds and cellular effects
Published in Pharmaceutical biology (01-11-2016)“…Context: "Aroeira" [Myracrodruon urundeuva Allemão (Anacardiaceae)] is a tree whose leaves have been studied for therapeutic purposes in medicine and…”
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Perspective on Dentoalveolar Manifestations Resulting From PHOSPHO1 Loss-of-Function: A Form of Pseudohypophosphatasia?
Published in Frontiers in dental medicine (01-02-2022)“…Mineralization of the skeleton occurs by several physicochemical and biochemical processes and mechanisms that facilitate the deposition of hydroxyapatite (HA)…”
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Laser phototherapy at high energy densities do not stimulate pre-osteoblast growth and differentiation
Published in Photomedicine and laser surgery (01-05-2013)“…The aim of this study is to evaluate the effects of red and infrared lasers at high energy densities on pre-osteoblast MC3T3 proliferation and differentiation…”
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Gene Therapy Using Adeno‐Associated Virus Serotype 8 Encoding TNAP‐D10 Improves the Skeletal and Dentoalveolar Phenotypes in Alpl−/− Mice
Published in Journal of bone and mineral research (01-09-2021)“…ABSTRACT Hypophosphatasia (HPP) is caused by loss‐of‐function mutations in the ALPL gene that encodes tissue‐nonspecific alkaline phosphatase (TNAP), whose…”
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Menadione and protocatechuic acid: A drug combination with antitumor effects in murine osteosarcoma cells
Published in Archives of biochemistry and biophysics (01-01-2024)“…Osteosarcoma (OS) is a primary malignant bone tumor that has an abnormal expression of oncogenesis and tumor suppressors and causes dysregulation of various…”
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Visualization of Mineral‐Targeted Alkaline Phosphatase Binding to Sites of Calcification In Vivo
Published in Journal of bone and mineral research (01-09-2020)“…ABSTRACT A mineral‐targeted form of recombinant tissue‐nonspecific alkaline phosphatase (TNAP), asfotase alfa, was approved multinationally as an enzyme…”
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Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP-D 10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia
Published in JBMR plus (01-01-2023)“…Hypophosphatasia (HPP), caused by loss-of-function mutations in the gene encoding tissue-nonspecific alkaline phosphatase (TNAP), is characterized by skeletal…”
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Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia
Published in JBMR plus (01-01-2023)“…ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is…”
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Ultrasensitive Diamond Microelectrode Application in the Detection of Ca2+ Transport by AnnexinA5-Containing Nanostructured Liposomes
Published in Biosensors (Basel) (14-07-2022)“…This report describes the innovative application of high sensitivity Boron-doped nanocrystalline diamond microelectrodes for tracking small changes in Ca2+…”
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Visualization of asfotase alfa-binding to sites of calcification in vivo
Published in Bone Reports (01-10-2020)Get full text
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