Search Results - "Amad, Ma’an"

Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor by FENWICK, Craig, AMAD, Ma'an, FADER, Lee D, FAUCHER, Anne-Marie, GARNEAU, Michel, JAKALIAN, Araz, KAWAI, Stephen, LAMORTE, Louie, LAPLANTE, Steven, LAIBIN LUO, MASON, Steve, POUPART, Marc-André, BAILEY, Murray D, RIOUX, Nathalie, SCHROEDER, Patricia, SIMONEAU, Bruno, TREMBLAY, Sonia, TSANTRIZOS, Youla, WITVROUW, Myriam, YOAKIM, Christiane, BETHELL, Richard, BÖS, Michael, BONNEAU, Pierre, CORDINGLEY, Michael, COULOMBE, René, DUAN, Jianmin, EDWARDS, Paul

“…BI 224436 is an HIV-1 integrase inhibitor with effective antiviral activity that acts through a mechanism that is distinct from that of integrase strand…”
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Preclinical Characterization of BI 201335, a C-Terminal Carboxylic Acid Inhibitor of the Hepatitis C Virus NS3-NS4A Protease by WHITE, Peter W, LLINAS-BRUNET, Montse, KUKOLJ, George, AMAD, Ma'an, BETHELL, Richard C, BOLGER, Gordon, CORDINGLEY, Michael G, JIANMIN DUAN, GARNEAU, Michel, LAGACE, Lisette, THIBEAULT, Diane

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Multicomponent mixed dopant optimization for rapid screening of polycyclic aromatic hydrocarbons using ultra high performance liquid chromatography coupled to atmospheric pressure photoionization high-resolution mass spectrometry by Amad, Salim Sioud, Ma'an, Al-Talla, Zeyad A.

“…RATIONALE To enhance the ionization efficiencies in atmospheric pressure photoionization mass spectrometry a dopant with favorable ionization energy such as…”
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A Novel Human Cytochrome P450, CYP26C1, Involved in Metabolism of 9-cis and All-trans Isomers of Retinoic Acid by Taimi, Mohammed, Helvig, Christian, Wisniewski, Jan, Ramshaw, Heather, White, Jay, Amad, Ma'an, Korczak, Bozena, Petkovich, Martin

“…Retinoids are potent regulators of cell proliferation, cell differentiation, and morphogenesis and are important therapeutic agents in oncology and…”
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The Liver Partition Coefficient-Corrected Inhibitory Quotient and the Pharmacokinetic-Pharmacodynamic Relationship of Directly Acting Anti-Hepatitis C Virus Agents in Humans by JIANMIN DUAN, BOLGER, Gordon, KUKOLJ, George, WHITE, Peter W, BETHELL, Richard C, CORDINGLEY, Michael G, GARNEAU, Michel, AMAD, Ma'an, BATONGA, Joëlle, MONTPETIT, Hélène, OTIS, François, JUTRAS, Martin, LAPEYRE, Nicole, RHEAUME, Manon

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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High temperature and solar radiation in the Red Sea enhance the dissolution of crude oil from surface films by Kottuparambil, Sreejith, Ashok, Ananya, López, Patricia, Amad, Maan H., Duarte, Carlos M., Agusti, Susana

“…The Red Sea is a hotspot of biodiversity susceptible to oil pollution. Besides, it is one of the warmest seas on the Earth with highly transparent waters. In…”
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Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases by Gagnon, Alexandre, Amad, Ma’an H., Bonneau, Pierre R., Coulombe, René, DeRoy, Patrick L., Doyon, Louise, Duan, Jianmin, Garneau, Michel, Guse, Ingrid, Jakalian, Araz, Jolicoeur, Eric, Landry, Serge, Malenfant, Eric, Simoneau, Bruno, Yoakim, Christiane

“…The SAR and PK studies of a series of thiotetrazolyl akynylacetanilides as potent inhibitors of the HIV-1 RT is reported. A series of aryl…”
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Analysis of some pharmaceuticals in municipal wastewater of Almadinah Almunawarah by Shraim, Amjad, Diab, Atef, Alsuhaimi, Awadh, Niazy, Esmail, Metwally, Mohammed, Amad, Maan, Sioud, Salim, Dawoud, Abdulilah

“…The chemical pollution of water resources is a major challenge facing the humanity in this century. Pharmaceuticals and personal care products (PPCPs) are a…”
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Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV‑1 by Fader, Lee D, Malenfant, Eric, Parisien, Mathieu, Carson, Rebekah, Bilodeau, François, Landry, Serge, Pesant, Marc, Brochu, Christian, Morin, Sébastien, Chabot, Catherine, Halmos, Ted, Bousquet, Yves, Bailey, Murray D, Kawai, Stephen H, Coulombe, René, LaPlante, Steven, Jakalian, Araz, Bhardwaj, Punit K, Wernic, Dominik, Schroeder, Patricia, Amad, Ma’an, Edwards, Paul, Garneau, Michel, Duan, Jianmin, Cordingley, Michael, Bethell, Richard, Mason, Stephen W, Bös, Michael, Bonneau, Pierre, Poupart, Marc-André, Faucher, Anne-Marie, Simoneau, Bruno, Fenwick, Craig, Yoakim, Christiane, Tsantrizos, Youla

“…An assay recapitulating the 3′ processing activity of HIV-1 integrase (IN) was used to screen the Boehringer Ingelheim compound collection. Hit-to-lead and…”
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The formation of [M-H]+ ions in N-alkyl-substituted thieno[3,4-c]-pyrrole-4,6-dione derivatives during atmospheric pressure photoionization mass spectrometry by Sioud, Salim, Kharbatia, Najeh, Amad, Maan H., Zhu, Zhiyong, Cabanetos, Clement, Lesimple, Alain, Beaujuge, Pierre

“…RATIONALE The formation of ions during atmospheric pressure photoionization (APPI) mass spectrometry in the positive mode usually provides radical cations…”
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Investigation of an enhanced resolution triple quadrupole mass spectrometer for high-throughput liquid chromatography/tandem mass spectrometry assays by Yang, Liyu, Amad, Ma'an, Winnik, Witold M., Schoen, Alan E., Schweingruber, Hans, Mylchreest, Iain, Rudewicz, Patrick J.

“…Triple quadrupole mass spectrometers, when operated in multiple reaction monitoring (MRM) mode, offer a unique combination of sensitivity, specificity, and…”
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Importance of gas-phase proton affinities in determining the electrospray ionization response for analytes and solvents by Amad, Ma'an H., Cech, Nadja B., Jackson, George S., Enke, Christie G.

“…The effect of gas‐phase proton transfer reactions on the mass spectral response of solvents and analytes with known gas‐phase proton affinities was evaluated…”
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Investigation of the ionization mechanism of polycyclic aromatic hydrocarbons using an ethanol/bromobenzene/chlorobenzene/anisole mixture as a dopant in liquid chromatography/atmospheric pressure photoionization mass spectrometry by Amad, Ma'an, Sioud, Salim

“…RATIONALE An ethanol‐based multicomponent dopant consisting of ethanol/chlorobenzene/bromobenzene/anisole (98.975:0.1:0.9:0.025, v/v/v/v) has been used as a…”
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Mass resolution of 11,000 to 22,000 with a multiple pass quadrupole mass analyzer by Amad, Ma’an H, Houk, R.S

“…CO + and N 2 + are separated with resolution of 11,000 [full width half maximum (FWHM)] using a conventional quadrupole mass spectrometer by applying square…”
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Fullerene-Catalyzed Reduction of Azo Derivatives in Water under UV Irradiation by Guo, Yong, Li, Wengang, Yan, Jingjing, Moosa, Basem, Amad, Ma'an, Werth, Charles J., Khashab, Niveen M.

“…Metal‐free fullerene (C60) was found to be an effective catalyst for the reduction of azo groups in basic aqueous solution under UV irradiation in the presence…”
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Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 2: Structure–activity relationships (SAR) of the C3-phenyl moiety by Fader, Lee D., Landry, Serge, Goulet, Sylvie, Morin, Sébastien, Kawai, Stephen H., Bousquet, Yves, Dion, Isabelle, Hucke, Oliver, Goudreau, Nathalie, Lemke, Christopher T., Rancourt, Jean, Bonneau, Pierre, Titolo, Steve, Amad, Ma’an, Garneau, Michel, Duan, Jianmin, Mason, Stephen, Simoneau, Bruno

“…Detailed structure–activity relationships of the C3-phenyl moiety that allow for the optimization of antiviral potency of a series of…”
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Discovery and Synthesis of C‑Nucleosides as Potential New Anti-HCV Agents by Draffan, Alistair G, Frey, Barbara, Pool, Brett, Gannon, Carlie, Tyndall, Edward M, Lilly, Michael, Francom, Paula, Hufton, Richard, Halim, Rosliana, Jahangiri, Saba, Bond, Silas, Nguyen, Van T. T, Jeynes, Tyrone P, Wirth, Veronika, Luttick, Angela, Tilmanis, Danielle, Thomas, Jesse D, Pryor, Melinda, Porter, Kate, Morton, Craig J, Lin, Bo, Duan, Jianmin, Kukolj, George, Simoneau, Bruno, McKercher, Ginette, Lagacé, Lisette, Amad, Ma’an, Bethell, Richard C, Tucker, Simon P

“…Nucleoside analogues have long been recognized as prospects for the discovery of direct acting antivirals (DAAs) to treat hepatitis C virus because they have…”
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High-Resolution Mass Spectrometry with a Multiple Pass Quadrupole Mass Analyzer by Amad, Ma'an H, Houk, R. S

“…The peak shape narrows and the resolution improves if the ions are simply reflected back and forth through a conventional quadrupole mass analyzer. CO+ and N2…”
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Dehydrodimerization of pterostilbene during electrospray ionization mass spectrometry by Raji, Misjudeen, Amad, Ma'an, Emwas, Abdel-Hamid

“…RATIONALE Pterostilbene is a member of the hydroxystilbene family of compounds commonly found in plants such as blueberry and grapes. During the analysis of…”
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Cross-species absorption, metabolism, distribution and pharmacokinetics of BI 201335, a potent HCV genotype 1 NS3/4A protease inhibitor by Duan, Jianmin, Yong, Chan-Loi, Garneau, Michel, Amad, Ma'an, Bolger, Gordon, De Marte, Josie, Montpetit, Hélène, Otis, Francois, Jutras, Martin, Rhéaume, Manon, White, Peter W., Llinàs-Brunet, Montse, Bethell, Richard C., Cordingley, Michael G.

“…The present study describes the cross-species absorption, metabolism, distribution and pharmacokinetics of BI 201335, a potent HCV protease inhibitor currently…”
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