Search Results - "Alzhrani, Rami M"
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Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages
Published in Biomaterials (01-11-2018)“…Drug resistance is one of the significant clinical burden in renal cell carcinoma (RCC). The development of drug resistance is attributed to many factors,…”
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PLGA-Based Nanomedicine: History of Advancement and Development in Clinical Applications of Multiple Diseases
Published in Pharmaceutics (06-12-2022)“…Research on the use of biodegradable polymers for drug delivery has been ongoing since they were first used as bioresorbable surgical devices in the 1980s. For…”
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Theoretical investigations on modeling blood flow through vessel for understanding effectiveness of magnetic nanocarrier drug delivery systems
Published in Frontiers in medicine (22-05-2024)“…For cancer therapy, the focus is now on targeting the chemotherapy drugs to cancer cells without damaging other normal cells. The new materials based on…”
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Fabrication, In Vitro, and In Vivo Assessment of Eucalyptol-Loaded Nanoemulgel as a Novel Paradigm for Wound Healing
Published in Pharmaceutics (01-09-2022)“…Wounds are the most common causes of mortality all over the world. Topical drug delivery systems are more efficient in treating wounds as compared to oral…”
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5
Biocompatibility and Hemolytic Activity Studies of Synthesized Alginate-Based Polyurethanes
Published in Polymers (20-05-2022)“…Many investigators have focused on the development of biocompatible polyurethanes by chemical reaction of functional groups contained in a spacer and…”
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Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation
Published in Frontiers in pharmacology (07-02-2023)“…The purpose of this study was to assess the parameters of doxorubicin (DOX) loaded lipid polymer hybrid nanoparticles (LPHNs) formulation development, and then…”
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Olive Leaf Extracts for a Green Synthesis of Silver-Functionalized Multi-Walled Carbon Nanotubes
Published in Journal of functional biomaterials (07-11-2022)“…Green biosynthesis, one of the most dependable and cost-effective methods for producing carbon nanotubes, was used to synthesize nonhazardous…”
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Folate Decorated Nanomicelles Loaded with a Potent Curcumin Analogue for Targeting Retinoblastoma
Published in Pharmaceutics (18-04-2017)“…The aim of this study was to develop a novel folate receptor-targeted drug delivery system for retinoblastoma cells using a promising anticancer agent,…”
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Causes of vancomycin dosing error; problem detection and practical solutions; a retrospective, single-center, cross-sectional study
Published in Saudi pharmaceutical journal (01-06-2021)“…Vancomycindosing error and inappropriate monitoring is a common problem in hospital daily practice. In King Abdulaziz Medical City (KAMC) in Jeddah, a high…”
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Altered Pharmacokinetics Parameters of Vancomycin in Patients with Hematological Malignancy with Febrile Neutropenia, a Bayesian Software Estimation
Published in Antibiotics (Basel) (29-05-2023)“…The pharmacokinetics of vancomycin vary significantly between specific groups of patients, such as critically ill patients and patients with hematological…”
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The Bayesian-Based Area under the Curve of Vancomycin by Using a Single Trough Level: An Evaluation of Accuracy and Discordance at Tertiary Care Hospital in KSA
Published in Healthcare (Basel) (27-01-2023)“…The AUC is the most accurate way to track the vancomycin level while the C is not an accurate surrogate. Most hospitals in Saudi Arabia are under-practicing…”
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Antimicrobial Activities Along With Spectrophotometric Assessment of Stability Constants of Copper (II) and Cobalt (II) With 1,2-Bis(2,5-dimethoxybenzylidene) Hydrazine
Published in International journal of analytical chemistry (2022)“…The stability constants of 1,2-bis(2,5-dimethoxybenzylidene) hydrazine (DMBH) were determined using the modified Job’s method with the addition of the UV-Vis…”
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Design and synthesis of drug hydrogels containing carboxymethylcellulose with honeycomb structure and pH-sensitivity as drug delivery systems for adriamycin, metformin, and naproxen
Published in International journal of biological macromolecules (01-06-2024)“…The aim of this research is to prepare and identify functionalized carboxymethylcellulose/mesoporous silica nanohydrogels (CMC/NH2-MCM-41) for obtaining a…”
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An environmentally sustainable synchronous spectrofluorimetric method coupled with second derivative signal processing for simultaneous determination of velpatasvir and simeprevir in pharmaceutical and plasma samples
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-02-2025)“…[Display omitted] •Spectrofluorimetric approach resolve velpatasvir and simeprevir overlapped spectra.•The method was validated using ICH guidelines.•Greenness…”
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Development of a fluorescent nano-sensing probe for atomoxetine analysis: Additional clinical pharmacokinetic study
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-12-2024)“…[Display omitted] •Fabrication of fluorescent carbon quantum dots from black-eyed pea beans for selective determination of atomoxetine.•Clinical…”
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Spectrophotometric determination of celecoxib and tramadol in the new approved formulated dosage form using principle component regression assistive model
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-11-2024)“…[Display omitted] •Simple and accurate spectrophotometric method for the determination of celecoxib and tramadol.•Principle component regression chemometric…”
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Analyzing energetics and dynamics of hepatitis C virus polymerase interactions with marine bacterial compounds: a computational study
Published in Molecular diversity (10-06-2024)“…Hepatitis C Virus (HCV) is a significant health concern affecting a large portion of the global population and is a major cause of acute liver diseases,…”
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Optoelectronic Analysis of Bismuth Sulfide and Copper-Doped Bismuth Sulfide Thin Films
Published in JOM (1989) (01-07-2022)“…Bismuth sulfide (Bi 2 S 3 ), which has an optimal bandgap range and high absorption coefficient, is an attractive candidate for photovoltaic applications…”
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A first-principles adsorption study of functionalized carbon, boron nitride, silicon carbon nanotubes with ifosfamide as vehicles for drug delivery: Thermal analysis
Published in Case studies in thermal engineering (01-11-2024)“…We investigated the adsorption of ifosfamide (IFS) on the outer surface of zigzag (10, 0) carbon nanotubes (CNT), boron nitride nanotubes (BNNT), and silicon…”
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Construction of a binary S-scheme S-g-C3N4/Co-ZF heterojunction with enhanced spatial charge separation for sunlight-driven photocatalytic performance
Published in RSC advances (16-08-2022)“…A step-scheme (S-scheme) photocatalyst made of sulfurized graphitic carbon nitride/cobalt doped zinc ferrite (S-g-C3N4/Co-ZF) was constructed using a…”
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