Search Results - "Alyautdin, Renad"

Targeted Delivery Methods for Anticancer Drugs by Veselov, Valery V, Nosyrev, Alexander E, Jicsinszky, László, Alyautdin, Renad N, Cravotto, Giancarlo

“…Several drug-delivery systems have been reported on and often successfully applied in cancer therapy. Cell-targeted delivery can reduce the overall toxicity of…”
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PCSK9 as a Target for Development of a New Generation of Hypolipidemic Drugs by Kuzmich, Nikolay, Andresyuk, Elena, Porozov, Yuri, Tarasov, Vadim, Samsonov, Mikhail, Preferanskaya, Nina, Veselov, Valery, Alyautdin, Renad

“…PCSK9 has now become an important target to create new classes of lipid-lowering drugs. The prevention of its interaction with LDL receptors allows an increase…”
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Temozolomide Efficacy and Metabolism: The Implicit Relevance of Nanoscale Delivery Systems by Petrenko, Daria, Chubarev, Vladimir, Syzrantsev, Nikita, Ismail, Nafeeza, Merkulov, Vadim, Sologova, Susanna, Grigorevskikh, Ekaterina, Smolyarchuk, Elena, Alyautdin, Renad

“…The most common primary malignant brain tumors in adults are gliomas. Glioblastoma is the most prevalent and aggressive tumor subtype of glioma. Current…”
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Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles by Kurakhmaeva, Kamila B., Djindjikhashvili, Irma A., Petrov, Valery E., Balabanyan, Vadim U., Voronina, Tatiana A., Trofimov, Sergey S., Kreuter, Jörg, Gelperina, Svetlana, Begley, David, Alyautdin, Renad N.

“…The nerve growth factor (NGF) is essential for the survival of both peripheral ganglion cells and central cholinergic neurons in the basal forebrain. The…”
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Apolipoprotein-mediated Transport of Nanoparticle-bound Drugs Across the Blood-Brain Barrier by Kreuter, Jörg, Shamenkov, Dmitry, Petrov, Valery, Ramge, Peter, Cychutek, Klaus, Koch-Brandt, Claudia, Alyautdin, Renad

“…Recent studies have shown that drugs that are normally unable to cross the blood-brain barrier (BBB) following intravenous injection can be transported across…”
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Gastroprotective effect of Berberis vulgaris on ethanol-induced gastric mucosal injury: Histopathological evaluations by Kapitonova, Marina, Gupalo, Sergey, Alyautdin, Renad, Ibrahim, Ibrahim Abdel Aziz, Salim, Norita, Ahmad, Azhar, Talip, Saiful Bahri, Nwe, Tin Moe, Morokhina, Svetlana

“…Modern treatment of peptic ulcers includes antibacterial and gastroprotective medications. However, current anti-ulcer drugs possess severe side effects…”
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A mouse model of weight-drop closed head injury：emphasis on cognitive and neurological deficiency by Khalin, Igor, Jamari, Nor, Abdul Razak, Nadiawati, Hasain, Zubaidah, Mohd Nor, Mohd, Zainudin, Mohd, Omar, Ainsah, Alyautdin, Renad

“…Traumatic brain injury（TBI） is a leading cause of death and disability in individuals worldwide.Producing a clinically relevant TBI model in small-sized…”
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The mitochondria free iron content to limit an isotope effect of (25)Mg (2+) in ATP synthesis: a caution by Svistunov, Andrey A, Napolov, Yuri K, Bukhvostov, Alexander A, Shatalov, Oleg A, Alyautdin, Renad N, Kuznetsov, Dmitry A

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Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles by ALYAUTDIN, R. N, PETROV, V. E, LANGER, K, BERTHOLD, A, KHARKEVICH, D. A, KREUTER, J

“…The possibility of using polysorbate 80-coated nanoparticles for the delivery of the water insoluble opioid agonist loperamide across the blood-brain barrier…”
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Fullerene-based Low Toxic Nanocationite Particles (Porphyrin Adducts of Cyclohexyl Fullerene-C60 ) to Treat Hypoxia-induced Mitochondrial Dysfunction in Mammalian Heart Muscle by Amirshahi, Nima, Alyautdin, Renad N, Sarkar, Saeed, Rezayat, Seyed M, Orlova, Marina A, Trushkov, Igor V, Buchachenko, Anatoly L, Kuznetsov, Dmitry A

“…Abstract Background This is the first report on the targeted delivery of fullerene-based low toxic nanocationite particles (porphyrin adducts of cyclohexyl…”
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The tissue-specific "ferromagnetic attack" on hyperactivation of ATP synthesis by magnesium-25 in mitochondria by Shatalov, Oleg A, Svistunov, Andrey A, Napolov, Yuri K, Bukhvostov, Alexander A, Kuznetsov, Dmitry A, Alyautdin, Renad N

“…A (25)Mg(2+)-operated hyper-activation of ATP synthesis has been investigated in mitochondria (Mt) isolated from iron-rich and iron-poor rat tissues: spleen,…”
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Fullerene-Interfaced Porphyrin Ligand in Affinity Chromatography of Membrane Proteins by Amirshahi, Nima, Alyautdin, Renad N, Rezayat, S. Mahdi, Sarkar, Saeed, Orlova, Marina A, Orlov, Alexey P, Poloznikov, Andrey A, Kuznetsov, Dmitry A

“…To purify the mammalian cell membrane porphyrin binding proteins (PBP), an original affinity chromatographic technique is proposed. The method is based on the…”
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Brain-derived neurotrophic factor delivered to the brain using poly (lactide-co-glycolide) nanoparticles improves neurological and cognitive outcome in mice with traumatic brain injury by Khalin, Igor, Alyautdin, Renad, Wong, Tin Wui, Gnanou, Justin, Kocherga, Ganna, Kreuter, Jörg

“…Currently, traumatic brain injury (TBI) is the leading cause of death or disabilities in young individuals worldwide. The multi-complexity of its pathogenesis…”
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O-BN002. Intravenous administration of poly(lactide-co-glycolide) nanoparticle encapsulating brain-derived neurotrophic factor promotes neuroprotection in an ischemic stroke model in the rat by Norsyafika Kamarudin, Siti, Iezhitsa, Igor, Tripathy, Minaketan, Alyautdin, Renad, Mohd Ismail, Nafeeza

“…Introduction. Poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) are biodegradable and biocompatible drug carriers and competent at delivering…”
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Liposomes in topical ophthalmic drug delivery: an update by Agarwal, Renu, Iezhitsa, Igor, Agarwal, Puneet, Abdul Nasir, Nurul Alimah, Razali, Norhafiza, Alyautdin, Renad, Ismail, Nafeeza Mohd

“…Topical route of administration is the most commonly used method for the treatment of ophthalmic diseases. However, presence of several layers of permeation…”
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Nanoscale drug delivery systems and the blood-brain barrier by Alyautdin, Renad, Khalin, Igor, Nafeeza, Mohd Ismail, Haron, Muhammad Huzaimi, Kuznetsov, Dmitry

“…The protective properties of the blood-brain barrier (BBB) are conferred by the intricate architecture of its endothelium coupled with multiple specific…”
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Neuroprotective effect of poly(lactic-co-glycolic acid) nanoparticle-bound brain-derived neurotrophic factor in a permanent middle cerebral artery occlusion model of ischemia in rats by Kamarudin, Siti Norsyafika, Iezhitsa, Igor, Tripathy, Minaketan, Alyautdin, Renad, Ismail, Nafeeza Mohd

“…Poly (lactide‑co‑glycolide) (PLGA) nanoparticles (NPs) are biodegradable carriers that participate in the transport of neuroprotective drugs across the blood…”
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Targeted delivery of brain-derived neurotrophic factor for the treatment of blindness and deafness by Khalin, Igor, Alyautdin, Renad, Kocherga, Ganna, Bakar, Muhamad Abu

“…Neurodegenerative causes of blindness and deafness possess a major challenge in their clinical management as proper treatment guidelines have not yet been…”
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Direct evidence that polysorbate-80-coated poly(butylcyanoacrylate) nanoparticles deliver drugs to the CNS via specific mechanisms requiring prior binding of drug to the nanoparticles by Kreuter, Jörg, Ramge, Peter, Petrov, Valery, Hamm, Stefan, Gelperina, Svetlana E, Engelhardt, Britta, Alyautdin, Renad, von Briesen, Hagen, Begley, David J

“…[corrected] It has recently been suggested that the poly(butylcyanoacrylate) (PBCA) nanoparticle drug delivery system has a generalized toxic effect on the…”
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Effects of topically applied tocotrienol on cataractogenesis and lens redox status in galactosemic rats by Abdul Nasir, Nurul Alimah, Agarwal, Renu, Vasudevan, Sushil, Tripathy, Minaketan, Alyautdin, Renad, Ismail, Nafeeza Mohd

“…Oxidative and nitrosative stress underlies cataractogenesis, and therefore, various antioxidants have been investigated for anticataract properties. Several…”
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