Search Results - "Alyar, Hamit"

Biochemical properties of Schiff bases derived from FDA-approved sulfa drugs: Synthesis, ADME/molecular docking studies, and anticancer activity by Alyar, Saliha, Alyar, Hamit, Özdemir Özmen, Ümmühan, Aktaş, Okan, Erdem, Kelime

“…•Four (L1-L4) new sulfa Schiff bases were synthesized and characterized.•The synthesized compounds were screened for their anticancer activity against the…”
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Synthesis, characterization, antimicrobial activity, carbonic anhydrase enzyme inhibitor effects, and computational studies on new Schiff bases of Sulfa drugs and their Pd(II), Cu(II) complexes by Alyar, Saliha, Şen, Cihan, Alyar, Hamit, Adem, Şevki, Kalkanci, Ayse, Ozdemir, Ummuhan Ozmen

“…New Schiff bases (E)N-(3,4-dimethylisoxazol-5-yl)-4-((2-hydroxy-3-methoxybenzylidene) amino)benzenesulfonamide (Ll),…”
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Synthesis, spectroscopic characterizations, enzyme inhibition, molecular docking study and DFT calculations of new Schiff bases of sulfa drugs by Alyar, Saliha, Şen, Tülin, Özmen, Ümmühan Özdemir, Alyar, Hamit, Adem, Şevki, Şen, Cihan

“…New Schiff bases were synthesized (Z)-4-((4-(diethylamino)benzylidene)amino)-N-(3,4-dimethylisoxazol-5-yl)benzenesulfonamide (L1) and…”
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Experimental and theoretical studies on a new sulfonamide derivative and its copper complex: Synthesis, FT-IR, NMR, DFT, molecular docking and in silico investigations by Alyar, Saliha, Bilkan, Mustafa Tuğfan, Karataş, Mehmet Fatih, Bilkan, Çiğdem, Alyar, Hamit

“…•A new sulfonamide derivative and its Cu(II) complex were produced and characterized.•CHNS, FT-IR, NMR, LC-MS, conductivity, magnetic susceptibility and TGA…”
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Synthesis, spectroscopic characterizations, carbonic anhydrase II inhibitory activity, anticancer activity and docking studies of new Schiff bases of sulfa drugs by Alyar, Saliha, Özmen, Ümmühan Özdemir, Adem, Şevki, Alyar, Hamit, Bilen, Esra, Kaya, Kerem

“…•New Schiff bases of sulfa drugs and their Pd(II) and Cu(II) complexes were synthesized.•Inhibitory activity of these compounds were evaluated against hCA II…”
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Biological evaluation of Schiff bases containing dopamine as antibacterial /antifungal and potential Anti COVID-19 agents: Design, synthesis, characterization, molecular docking studies, and ADME properties by Ünlü, Ayse, Özmen, Ümmühan Özdemir, Alyar, Saliha, Öztürk, Ali, Alyar, Hamit, Gündüzalp, Ayla Balaban

“…•A new dopamine Schiff bases were synthesized as antimicrobial and potential Anti COVID-19 agents:•The antimicrobial properties of the synthesized dopamine…”
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Sulfonyl hydrazone derivatives containing acetonaphtone as anticholinesterase inhibitors for the treatment of Alzheimer's: X-ray single-crystal analysis, and multifaced theoretical calculations by Özdemir Özmen, Ümmühan, Alyar, Saliha, Bilen Ayan, Esra, Canbolat, Nüveyre, Hamurcu, Fatma, Alyar, Hamit, Muhammet, Sinan Mithat, Kaya, Kerem

“…•2-Hydroxy-1-acetonaphthone-ethanesulfonylhydrazone was investigated by X-ray diffraction.•Anti-cholinesterase activity of sulfonylhydrazone compounds were…”
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Experimental Spectroscopic and Computational Studies on A New Synthesized Sulfisoxazole Derivative; Molecular Docking, Drug-likeness, ADME, Toxicity Predictions and Carbonic Anhydrase II Activity Investigations by Bilkan, Mustafa Tuğfan, Karataş, Mehmet Fatih, Bilkan, Çiğdem, Alyar, Hamit, Alyar, Saliha

“…In this paper, 5-Dimethylamino-2-hydroxy-3-methoxy benzaldehyde sulfisoxazole (5DHMS) and Cu(5DHMS)2 compounds have been synthesized. The molecular structure…”
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Synthesis, characterization, spectroscopic properties, DFT calculations and antimicrobial activities of p-toluenesulfonamide,N,N′-1,3-propanediylbis(ptspr) and [Cu(II) (phenanthroline)2]ptspr by Akyıldız, Fatih, Alyar, Saliha, Bilkan, Mustafa Tuğfan, Alyar, Hamit

“…In this paper, p-toluenesulfonamide,N,N′-1,3-propanediylbis (ptspr) and [Cu(II) (phenanthroline)2]ptspr compounds has been synthesized for the first time and…”
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Biologically active Schiff bases containing thiophene/furan ring and their copper(II) complexes: Synthesis, spectral, nonlinear optical and density functional studies by Gündüzalp, Ayla Balaban, Özsen, İffet, Alyar, Hamit, Alyar, Saliha, Özbek, Neslihan

“…Schiff bases; 1,8-bis(thiophene-2-carboxaldimine)-p-menthane (L1) and 1,8-bis(furan-2-carboxaldimine)-p-menthane (L2) have been synthesized and characterized…”
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Synthesis, characterization and anti-microbial evaluation of Cu(II), Ni(II), Pt(II) and Pd(II) sulfonylhydrazone complexes; 2D-QSAR analysis of Ni(II) complexes of sulfonylhydrazone derivatives by Özbek, Neslihan, Alyar, Saliha, Alyar, Hamit, Şahin, Ertan, Karacan, Nurcan

“…Plot of observed versus calculated pMIC values of training sets for: (a) E. coli and (b) S. aureus [Display omitted] ► New original sulfonylhydrazine and…”
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Synthesis, characterization, computational studies, antimicrobial activities and carbonic anhydrase inhibitor effects of 2-hydroxy acetophenone-N-methyl p-toluenesulfonylhydrazone and its Co(II), Pd(II), Pt(II) complexes by Özbek, Neslihan, Alyar, Saliha, Memmi, Burcu Koçak, Gündüzalp, Ayla Balaban, Bahçeci, Zafer, Alyar, Hamit

“…2-Hydroxyacetophenone-N-methyl p-toluenesulfonylhydrazone (afptsmh) derived from p-toluenesulfonicacid-1-methylhydrazide (ptsmh) and its Co(II), Pd(II), Pt(II)…”
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Synthesis, characterization, antibacterial activity and quantum chemical studies of N’-Acetyl propane sulfonic acid hydrazide by Alyar, Saliha, Alyar, Hamit, Ozdemir, Ummuhan Ozmen, Sahin, Omer, Kaya, Kerem, Ozbek, Neslihan, Gunduzalp, Ayla Balaban

“…N’-Acetyl propane sulfonic acid hydrazide has been synthesized for the first time and investigated its antibacterial activity. Also 1H and 13C shielding…”
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Conformational analysis, vibrational and NMR spectroscopic study of the methanesulfonamide-N,N′-1,2-ethanediylbis by Alyar, Hamit, Ünal, Arslan, Özbek, Neslihan, Alyar, Saliha, Karacan, Nurcan

“…[Display omitted] ► Spectroscopic features of msen were investigated by infrared, Raman, NMR and DFT. ► A detailed conformational analysis of the title…”
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Synthesis, characterization and antimicrobial activity of m-toluenesulfonamide, N,N′-1,2-ethanediylbis (mtsen) and [Cu(II)(phenanthroline)2]mtsen complex by Alyar, Hamit, Alyar, Saliha, Ünal, Arslan, Özbek, Neslihan, Şahin, Ertan, Karacan, Nurcan

“…► M-toluenesulfonamide, N,N′-1,2-ethanediylbis (mtsen) and [Cu(II)(phenanthroline)2]mtsen compounds were synthesized. ► The structure of msen was proved by…”
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Synthesis, molecular structure, spectroscopic and theoretical studies on E-2-ethoxy-4-[(4-ethoxyphenylimino)methyl]phenol by Zeyrek, Celal Tuğrul, Alpaslan, Gökhan, Alyar, Hamit, Yıldız, Mustafa, Dilek, Nefise, Ünver, Hüseyin

“…[Display omitted] •E-2-ethoxy-4-[(4-ethoxyphenylimino)methyl]phenol has been synthesized.•The molecular structure obtained from X-ray single-crystal…”
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Synthesis, characterization and antimicrobial activity of m-toluenesulfonamide, N,Na2-1,2-ethanediylbis (mtsen) and [Cu(II)(phenanthroline)2]mtsen complex by Alyar, Hamit, Alyar, Saliha, Uenal, Arslan, Oezbek, Neslihan, Sahin, Ertan, Karacan, Nurcan

“…M-toluenesulfonamide, N,Na2-1,2-ethanediylbis (a disulfonamide compound, mtsen) and [Cu(II)(phenanthroline)2]mtsen compounds were newly synthesized. The…”
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