Search Results - "Alyamkina, Ekaterina A"

Identification of cancer stem cells and a strategy for their elimination by Dolgova, Evgenia V, Alyamkina, Ekaterina A, Efremov, Yaroslav R, Nikolin, Valeriy P, Popova, Nelly A, Tyrinova, Tamara V, Kozel, Artem V, Minkevich, Alexandra M, Andrushkevich, Oleg M, Zavyalov, Evgeniy L, Romaschenko, Alexander V, Bayborodin, Sergey I, Taranov, Oleg S, Omigov, Vladimir V, Shevela, Ekaterina Ya, Stupak, Vyacheslav V, Mishinov, Sergey V, Rogachev, Vladimir A, Proskurina, Anastasia S, Mayorov, Vladimir I, Shurdov, Mikhail A, Ostanin, Alexander A, Chernykh, Elena R, Bogachev, Sergey S

“…It has been established previously that up to 40% of mouse CD34 + hematopoietic stem cells are capable of internalizing exogenous dsDNA fragments both in vivo…”
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Delivery and processing of exogenous double-stranded DNA in mouse CD34+ hematopoietic progenitor cells and their cell cycle changes upon combined treatment with cyclophosphamide and double-stranded DNA by Dolgova, Evgenia V., Efremov, Yaroslav R., Orishchenko, Konstantin E., Andrushkevich, Oleg M., Alyamkina, Ekaterina A., Proskurina, Anastasia S., Bayborodin, Sergey I., Nikolin, Valeriy P., Popova, Nelly A., Chernykh, Elena R., Ostanin, Alexandr A., Taranov, Oleg S., Omigov, Vladimir V., Minkevich, Alexandra M., Rogachev, Vladimir A., Bogachev, Sergey S., Shurdov, Mikhail A.

“…We previously reported that fragments of exogenous double-stranded DNA can be internalized by mouse bone marrow cells without any transfection. Our present…”
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Cytotoxic activity of ex-vivo generated IFNα-induced monocyte-derived dendritic cells in brain glioma patients by Tyrinova, Tamara V., Leplina, Olga Yu, Mishinov, Sergey V., Tikhonova, Marina A., Shevela, Ekaterina Ya, Stupak, Vyacheslav V., Pendyurin, Ivan V., Shilov, Alexander G., Alyamkina, Ekaterina A., Rubtsova, Nadezda V., Bogachev, Sergey S., Ostanin, Alexander A., Chernykh, Elena R.

“…•IFNα-induced DCs trigger apoptosis of tumor line HEp-2 through TNFα-dependent pathway.•DCs in high-grade glioma patients lack the cytotoxic activity against…”
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“Delayed death” phenomenon: A synergistic action of cyclophosphamide and exogenous DNA by Dolgova, Evgenia V., Proskurina, Anastasia S., Nikolin, Valeriy P., Popova, Nelly A., Alyamkina, Ekaterina A., Orishchenko, Konstantin E., Rogachev, Vladimir A., Efremov, Yaroslav R., Dubatolova, Tatiana D., Prokopenko, Anastasia V., Chernykh, Elena R., Ostanin, Alexandr A., Taranov, Oleg S., Omigov, Vladimir V., Zagrebelniy, Stanislav N., Bogachev, Sergey S., Shurdov, Mikhail A.

“…Morbidity and mortality in mice were observed upon administration of exogenous DNA following their pre-treatment with a cytostatic agent cyclophosphamide. Upon…”
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Results of multicenter double-blind placebo-controlled phase II clinical trial of Panagen preparation to evaluate its leukostimulatory activity and formation of the adaptive immune response in patients with stage II-IV breast cancer by Proskurina, Anastasia S, Gvozdeva, Tatiana S, Alyamkina, Ekaterina A, Dolgova, Evgenia V, Orishchenko, Konstantin E, Nikolin, Valeriy P, Popova, Nelly A, Sidorov, Sergey V, Chernykh, Elena R, Ostanin, Alexandr A, Leplina, Olga Y, Dvornichenko, Victoria V, Ponomarenko, Dmitriy M, Soldatova, Galina S, Varaksin, Nikolay A, Ryabicheva, Tatiana G, Uchakin, Peter N, Zagrebelniy, Stanislav N, Rogachev, Vladimir A, Bogachev, Sergey S, Shurdov, Mikhail A

“…We performed a multicenter, double-blind, placebo-controlled, phase II clinical trial of human dsDNA-based preparation Panagen in a tablet form. In total, 80…”
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Erratum to: Results of multicenter double-blind placebo-controlled phase II clinical trial of Panagen preparation to evaluate its leukostimulatory activity and formation of the adaptive immune response in patients with stage II-IV breast cancer by Proskurina, Anastasia S, Gvozdeva, Tatiana S, Alyamkina, Ekaterina A, Dolgova, Evgenia V, Orishchenko, Konstantin E, Nikolin, Valeriy P, Popova, Nelly A, Sidorov, Sergey V, Chernykh, Elena R, Ostanin, Alexandr A, Leplina, Olga Y, Dvornichenko, Victoria V, Ponomarenko, Dmitriy M, Soldatova, Galina S, Varaksin, Nikolay A, Ryabicheva, Tatiana G, Uchakin, Peter N, Zagrebelniy, Stanislav N, Rogachev, Vladimir A, Bogachev, Sergey S, Shurdov, Mikhail A

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Combination of cyclophosphamide and double-stranded DNA demonstrates synergistic toxicity against established xenografts by Alyamkina, Ekaterina A, Nikolin, Valeriy P, Popova, Nelly A, Minkevich, Alexandra M, Kozel, Artem V, Dolgova, Evgenia V, Efremov, Yaroslav R, Bayborodin, Sergey I, Andrushkevich, Oleg M, Taranov, Oleg S, Omigov, Vladimir V, Rogachev, Vladimir A, Proskurina, Anastasia S, Vereschagin, Evgeniy I, Kiseleva, Elena V, Zhukova, Maria V, Ostanin, Alexandr A, Chernykh, Elena R, Bogachev, Sergey S, Shurdov, Mikhail A

“…Extracellular double-stranded DNA participates in various processes in an organism. Here we report the suppressive effects of fragmented human double-stranded…”
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Effects of human exogenous DNA on production of perforin-containing CD8+ cytotoxic lymphocytes in laboratory setting and clinical practice by Alyamkina, Ekaterina A., Leplina, Olga Y., Ostanin, Alexandr A., Chernykh, Elena R., Nikolin, Valeriy P., Popova, Nelly A., Proskurina, Anastasia S., Gvozdeva, Tatiana S., Dolgova, Evgenia V., Orishchenko, Konstantin E., Rogachev, Vladimir A., Sidorov, Sergey V., Varaksin, Nikolay A., Ryabicheva, Tatiana G., Bogachev, Sergey S., Shurdov, Mikhail A.

“…► Polycytostatic treatment results in suppression of tumor growth in mice. ► Human DNA preparation significantly enhances anticancer effects of cytostatic…”
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Exogenous allogenic fragmented double-stranded DNA is internalized into human dendritic cells and enhances their allostimulatory activity by Alyamkina, Ekaterina A., Dolgova, Evgenia V., Likhacheva, Anastasia S., Rogachev, Vladimir A., Sebeleva, Tamara E., Nikolin, Valeriy P., Popova, Nelly A., Kiseleva, Elena V., Orishchenko, Konstantin E., Sakhno, Ludmila V., Gel’fgat, Evgeniy L., Ostanin, Alexandr A., Chernykh, Elena R., Zagrebelniy, Stanislav N., Bogachev, Sergey S., Shurdov, Mikhail A.

“…Exogenous allogenic DNA as nucleosome-free fragments reaches main cellular compartments (cytoplasm, nucleus) of human dendritic cells and deposits in the…”
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Effect of double-stranded DNA on maturation of dendritic cells in vitro by Alyamkina, Ekaterina A., Leplina, Olga Y., Sakhno, Ludmila V., Chernykh, Elena R., Ostanin, Alexandr A., Efremov, Yaroslav R., Shilov, Alexandr G., Proskurina, Anastasia S., Orishchenko, Konstantin E., Dolgova, Evgenia V., Rogachev, Vladimir A., Nikolin, Valeriy P., Popova, Nelly A., Zagrebelniy, Stanislav N., Bogachev, Sergey S., Shurdov, Mikhail A.

“…A preparation of human genomic fragmented double-stranded DNA (dsDNA) was used as maturation stimulus in cultures of human dendritic cells (DCs) generated in…”
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A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA preparation by Alyamkina, Ekaterina A, Nikolin, Valeriy P, Popova, Nelly A, Dolgova, Evgenia V, Proskurina, Anastasia S, Orishchenko, Konstantin E, Efremov, Yaroslav R, Chernykh, Elena R, Ostanin, Alexandr A, Sidorov, Sergey V, Ponomarenko, Dmitriy M, Zagrebelniy, Stanislav N, Bogachev, Sergey S, Shurdov, Mikhail A

“…Immunization of mice with tumor homogenate after combined treatment with cyclophosphamide (CP) and double-stranded DNA (dsDNA) preparation is effective at…”
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Combined therapy with cyclophosphamide and DNA preparation inhibits the tumor growth in mice by Alyamkina, Ekaterina A, Dolgova, Evgenia V, Likhacheva, Anastasia S, Rogachev, Vladimir A, Sebeleva, Tamara E, Nikolin, Valeriy P, Popova, Nelly A, Orishchenko, Konstantin E, Strunkin, Dmitriy N, Chernykh, Elena R, Zagrebelniy, Stanislav N, Bogachev, Sergei S, Shurdov, Mikhail A

“…When cyclophosphamide and preparations of fragmented exogenous genomic double stranded DNA were administered in sequence, the regressive effect on the tumor…”
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