Search Results - "Aly, Theresa A."
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Extreme Genetic Risk for Type 1A Diabetes
Published in Proceedings of the National Academy of Sciences - PNAS (19-09-2006)“…Type 1A diabetes (T1D) is an autoimmune disorder the risk of which is increased by specific HLA DR/DQ alleles [e.g., DRB1*03DQB1*0201 (DR3) or…”
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Analysis of Single Nucleotide Polymorphisms Identifies Major Type 1A Diabetes Locus Telomeric of the Major Histocompatibility Complex
Published in Diabetes (New York, N.Y.) (01-03-2008)“…Analysis of Single Nucleotide Polymorphisms Identifies Major Type 1A Diabetes Locus Telomeric of the Major Histocompatibility Complex Theresa A. Aly 1 , 2 ,…”
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HLA-DPB10402 Protects Against Type 1A Diabetes Autoimmunity in the Highest Risk DR3-DQB10201/DR4-DQB10302 DAISY Population
Published in Diabetes (New York, N.Y.) (01-09-2007)“…HLA-DPB1*0402 Protects Against Type 1A Diabetes Autoimmunity in the Highest Risk DR3-DQB1*0201/DR4-DQB1*0302 DAISY Population Erin E. Baschal 1 , Theresa A…”
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Defining multiple common “completely” conserved major histocompatibility complex SNP haplotypes
Published in Clinical immunology (Orlando, Fla.) (01-08-2009)“…Abstract The availability of both HLA data and genotypes for thousands of SNPs across the major histocompatibility complex (MHC) in 1240 complete families of…”
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Two Single Nucleotide Polymorphisms Identify the Highest-Risk Diabetes HLA Genotype
Published in Diabetes (New York, N.Y.) (01-11-2008)“…Two Single Nucleotide Polymorphisms Identify the Highest-Risk Diabetes HLA Genotype Potential for Rapid Screening Jennifer M. Barker , Taylor M. Triolo ,…”
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Two Single Nucleotide Polymorphisms Identify the Highest-Risk Diabetes HLA Genotype : Potential for Rapid Screening
Published in Diabetes (New York, N.Y.) (01-11-2008)“…People with the HLA genotype DRB1*0301-DQA1*0501-DQB1*0201/DRB1*04-DQA1*0301-DQB1*0302 (DR3/4-DQ8) are at the highest risk of developing type 1 diabetes. We…”
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Multi-SNP analysis of MHC region : Remarkable conservation of HLA-A1-B8-DR3 haplotype
Published in Diabetes (New York, N.Y.) (01-05-2006)“…Technology has become available to cost-effectively analyze thousands of single nucleotide polymorphisms (SNPs). We recently confirmed by genotyping a small…”
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Genetic prediction of autoimmunity: Initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4–DQ8 relatives of patients with type 1A diabetes
Published in Journal of autoimmunity (2005)“…In this study, the combined risk for expressing anti-islet autoantibodies and type 1A diabetes (T1D) was prospectively examined in 85 sampled relatives who had…”
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Multi-SNP Analysis of MHC Region
Published in Diabetes (New York, N.Y.) (01-05-2006)“…Multi-SNP Analysis of MHC Region Remarkable Conservation of HLA-A1-B8-DR3 Haplotype Theresa A. Aly 1 , Elise Eller 1 , Akane Ide 1 , Katherine Gowan 2 ,…”
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High Density SNP Analysis of the MHC Region Reveals Multiple Loci for Type 1A Diabetes
Published in Clinical immunology (Orlando, Fla.) (01-01-2007)Get full text
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Protein Kinase Cδ is a downstream effector of oncogenic KRAS in lung tumors1
Published in Cancer research (Chicago, Ill.) (18-02-2011)“…Oncogenic activation of KRAS occurs commonly in non-small cell lung cancer (NSCLC), but strategies to therapeutically target this pathway have been challenging…”
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