Search Results - "Aly, Enayat I."
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HER2 Kinase-Targeted Breast Cancer Therapy: Design, Synthesis, and In Vitro and In Vivo Evaluation of Novel Lapatinib Congeners as Selective and Potent HER2 Inhibitors with Favorable Metabolic Stability
Published in Journal of medicinal chemistry (24-12-2020)“…HER2 kinase as a well-established target for breast cancer (BC) therapy is associated with aggressive clinical outcomes; thus, herein we present structural…”
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4-Substituted-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine Derivatives: Design, Synthesis, Antitumor and EGFR Tyrosine Kinase Inhibitory Activity
Published in Chemical biology & drug design (01-05-2015)“…Four series of some 4‐substituted‐1‐phenyl‐1H‐pyrazolo[3,4‐d]pyrimidine derivatives 5a–f, 6a–f, 8a–f, and 9a–f were designed to be screened for their antitumor…”
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Synthesis and Antitubercular Activity of 6-Chloro (Unsubstituted)- 2-Methoxy-9-Substituted Acridine Derivatives
Published in Archives of pharmacal research (2004)“…Several analogues of the general formulae 2-methoxy-9-substituted acridine and 6-chloro-2-methoxy-9-substituted acridine were synthesized and evaluated in…”
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Synthesis and antitubercular activity of 6-chloro (unsubstituted)- 2-methoxy-9-substituted acridine derivatives
Published in Archives of pharmacal research (01-07-2004)“…Several analogues of the general formulae 2-methoxy-9-substituted acridine and 6-chloro-2-methoxy-9-substituted acridine were synthesized and evaluated in…”
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4‐Substituted‐1‐phenyl‐1 H ‐pyrazolo[3,4‐ d ]pyrimidine Derivatives: Design, Synthesis, Antitumor and EGFR Tyrosine Kinase Inhibitory Activity
Published in Chemical biology & drug design (01-05-2015)“…Four series of some 4‐substituted‐1‐phenyl‐1 H ‐pyrazolo[3,4‐ d ]pyrimidine derivatives 5a – f , 6a – f , 8a – f , and 9a – f were designed to be screened for…”
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