Search Results - "Alwayn, Ian P"
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Donor-Recipient Weight and Sex Mismatch and the Risk of Graft Loss in Renal Transplantation
Published in Clinical journal of the American Society of Nephrology (03-04-2017)“…Relatively smaller kidney donor to recipient size is proposed to result in higher graft loss due to nephron underdosing and hyperfiltration injury, but the…”
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2
Evaluation of Liver Graft Donation After Euthanasia
Published in JAMA surgery (01-10-2020)“…The option of donating organs after euthanasia is not well known. Assessment of the results of organ transplants with grafts donated after euthanasia is…”
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3
A cell-free nutrient-supplemented perfusate allows four-day ex vivo metabolic preservation of human kidneys
Published in Nature communications (13-05-2024)“…The growing disparity between the demand for transplants and the available donor supply, coupled with an aging donor population and increasing prevalence of…”
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4
Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys
Published in Frontiers in immunology (13-07-2022)“…The gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor…”
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5
The role of flavin mononucleotide (FMN) as a potentially clinically relevant biomarker to predict the quality of kidney grafts during hypothermic (oxygenated) machine perfusion
Published in PloS one (23-06-2023)“…Hypothermic machine perfusion (HMP) provides preservation superior to cold storage and may allow for organ assessment prior to transplantation. Since flavin…”
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6
Donor-Derived Mesenchymal Stem Cells Suppress Alloreactivity of Kidney Transplant Patients
Published in Transplantation (27-03-2009)“…Human mesenchymal stem cells (MSC) have immunosuppressive capacities. Although their efficacy is currently studied in graft-versus-host disease, their effect…”
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Equivalent Long-term Transplantation Outcomes for Kidneys Donated After Brain Death and Cardiac Death: Conclusions From a Nationwide Evaluation
Published in EClinicalMedicine (01-10-2018)“…Despite growing waiting lists for renal transplants, hesitations persist with regard to the use of deceased after cardiac death (DCD) renal grafts. We…”
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8
Complex Vascular Anatomy in Live Kidney Donation : Imaging and Consequences for Clinical Outcome
Published in Transplantation (27-06-2008)“…Live donor kidneys with multiple arteries are associated with surgical complexity for removal and increased rate of recipient ureteral complications. We…”
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9
Risk analysis of extended pancreas donor selection criteria
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-10-2019)“…The success of pancreas transplantation, in combination with a stable number of available allografts has resulted in an increasing waiting list. This study…”
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10
Laparoscopic Donor Nephrectomy : A Plea for the Right-Sided Approach
Published in Transplantation (15-03-2009)“…Laparoscopic donor nephrectomy (LDN) has become the preferred procedure for live donor nephrectomy. Most transplant surgeons are reluctant toward right-sided…”
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11
Omega-3 fatty acids improve hepatic steatosis in a murine model : Potential implications for the marginal steatotic liver donor
Published in Transplantation (15-03-2005)“…The presence of nonalcoholic fatty liver disease often precludes potential organs from being used for transplantation. To date, there is no adequate treatment…”
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12
The current practice of live donor nephrectomy in Europe
Published in Transplantation (15-10-2006)“…The increasing number of live kidney donors in the last decade has stimulated interest in the surgical technique of donor nephrectomy. In this study, we…”
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13
Prolonged warm ischemia time is associated with graft failure and mortality after kidney transplantation
Published in Kidney international (01-03-2016)“…Warm ischemia time is a potentially modifiable insult to transplanted kidneys, but little is known about its effect on long-term outcomes. Here we conducted a…”
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14
Hepatic steatosis is not always a contraindication for cadaveric liver transplantation
Published in HPB (Oxford, England) (01-06-2011)“…Abstract Background Macrovesicular steatosis is assumed to be an important risk factor for early allograft dysfunction (EAD) after orthotopic liver…”
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15
Certification Training and Liver Transplant Experience Improves Liver Procurement Outcomes: The Dutch Approach
Published in Transplantation (01-10-2024)“…This study investigates the impact of certification training and liver transplant experience on procurement outcomes of deceased donor liver procurement in the…”
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16
The Non-Muscle-Splitting Mini-Incision Donor Nephrectomy Remains a Feasible Technique in the Laparoscopic Era of Living Kidney Donation
Published in Transplantology (Basel, Switzerland) (01-03-2023)“…Laparoscopic donor nephrectomy (LDN) is the current gold standard in kidney donation. Mini-incision open donor nephrectomy (MINI) techniques have been used…”
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17
Prevention of intra-abdominal adhesions using the antiangiogenic COX-2 inhibitor celecoxib
Published in Annals of surgery (01-07-2005)“…To determine the effects of COX-2 specific inhibitors on postoperative adhesion formation. Intra-abdominal adhesions are the major cause of intestinal…”
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18
Severe COVID‐19 in a renal transplant recipient: A focus on pharmacokinetics
Published in American journal of transplantation (01-07-2020)“…The current coronavirus disease 2019 (COVID‐19) pandemic requires extra attention for immunocompromised patients, including solid organ transplant recipients…”
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Extracellular Vesicles Released During Normothermic Machine Perfusion Are Associated With Human Donor Kidney Characteristics
Published in Transplantation (01-12-2022)“…Extracellular vesicles (EVs) are tissue-specific particles released by cells containing valuable diagnostic information in the form of various biomolecules…”
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20
Psychosocial and physical impairment after mini-incision open and laparoscopic donor nephrectomy : A prospective study
Published in Transplantation (27-11-2006)“…The aim of the present study was to prospectively investigate how mini-incision donor nephrectomy (MIDN) and laparoscopic donor nephrectomy (LDN) affected the…”
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