Search Results - "Alvim, Renata G F"
-
1
Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice
Published in Vaccines (Basel) (01-08-2022)“…Despite the intramuscular route being the most used vaccination strategy against SARS-CoV-2, the intradermal route has been studied around the globe as a…”
Get full text
Journal Article -
2
Zika virus-like particles (VLPs): Stable cell lines and continuous perfusion processes as a new potential vaccine manufacturing platform
Published in Vaccine (08-11-2019)“…Zika virus (ZIKV) was first detected in Brazil in 2015 and then rapidly spread to more than 80 countries in Africa, Asia and the Americas. ZIKV infection was…”
Get full text
Journal Article -
3
Immunogenicity, Effectiveness, and Safety of Inactivated Virus (CoronaVac) Vaccine in a Two-Dose Primary Protocol and BNT162b2 Heterologous Booster in Brazil (Immunita-001): A One Year Period Follow Up Phase 4 Study
Published in Frontiers in immunology (09-06-2022)“…BackgroundEffective and safe vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are critical to controlling the COVID-19 pandemic…”
Get full text
Journal Article -
4
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum
Published in Frontiers in immunology (30-06-2022)“…The SARS-CoV-2 pandemic has had a social and economic impact worldwide, and vaccination is an efficient strategy for diminishing those damages. New adjuvant…”
Get full text
Journal Article -
5
Antibody response and soluble mediator profile in the first six months following acute SARS-CoV-2 infection
Published in Scientific reports (30-10-2023)“…The COVID-19 pandemic has caused a severe global health and economic crisis, with significant consequences for human mortality and morbidity. Therefore, there…”
Get full text
Journal Article -
6
Process intensification for the production of yellow fever virus‐like particles as potential recombinant vaccine antigen
Published in Biotechnology and bioengineering (01-09-2021)“…Yellow fever (YF) is a life‐threatening viral disease endemic in parts of Africa and Latin America. Although there is a very efficacious vaccine since the…”
Get full text
Journal Article -
7
From a recombinant key antigen to an accurate, affordable serological test: Lessons learnt from COVID-19 for future pandemics
Published in Biochemical engineering journal (01-08-2022)“…Serological tests detect antibodies generated by infection or vaccination, and are indispensable tools along different phases of a pandemic, from early…”
Get full text
Journal Article -
8
The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self
Published in The Journal of experimental medicine (06-09-2021)“…Besides antigen-specific responses to viral antigens, humoral immune response in virus infection can generate polyreactive and autoreactive antibodies. Dengue…”
Get full text
Journal Article -
9
Conformational stability of SARS-CoV-2 glycoprotein spike variants
Published in iScience (20-01-2023)“…The severe acute respiratory syndrome spread worldwide, causing a pandemic. SARS-CoV-2 mutations have arisen in the spike, a glycoprotein at the viral envelope…”
Get full text
Journal Article -
10
Polyclonal F(ab’)2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency
Published in iScience (19-11-2021)“…We used the recombinant trimeric spike (S) glycoprotein in the prefusion conformation to immunize horses for the production of hyperimmune globulins against…”
Get full text
Journal Article