Search Results - "Alves, Tânia Maria Almeida"

Fungi in glacial ice of Antarctica: diversity, distribution and bioprospecting of bioactive compounds by de Menezes, Graciéle Cunha Alves, Porto, Bárbara Alves, Amorim, Soraya Sander, Zani, Carlos Leomar, de Almeida Alves, Tânia Maria, Junior, Policarpo Ademar Sales, Murta, Silvane Maria Fonseca, Simões, Jefferson Cardia, Cota, Betania Barros, Rosa, Carlos Augusto, Rosa, Luiz Henrique

“…We identified cultivable fungi present in the glacial ice fragments collected in nine sites across Antarctica Peninsula and assessed their abilities to produce…”
Get full text

Natural Occurring Phenolic Derivatives from Mauritia flexuosa (Buriti) Stems and Their Potential Antibacterial Activity against Methicillin‐Resistant Staphylococcus aureus (MRSA) by Oliveira, Djalma Menezes, Oliveira, Diego Batista Carneiro, Nunes, Yule Roberta Ferreira, Almeida Alves, Tânia Maria, Kohlhoff, Markus, Andrade, Anderson Assunção, Cota, Betania Barros

“…Mauritia flexuosa Linnaeus filius (buriti or aguage; Arecaceae) is a palm used by traditional medicine in Brazil to treat dysentery and diarrhea. Our group…”
Get full text

A new insight into purinergic pharmacology: Three fungal species as natural P2X7R antagonists by Soares‐Bezerra, Rômulo José, Silva Ferreira, Natiele Carla, Almeida Alves, Tânia Maria, Zani, Carlos Leomar, Rosa, Luiz Henrique, Faria, Robson Xavier, Silva Frutuoso, Válber, Alves, Luiz Anastacio

“…P2X7 is a purinergic receptor involved in important physiological functions and pathological processes, such as inflammation, neurodegeneration, and pain…”
Get full text

Searching for plant-derived antivirals against dengue virus and Zika virus by de Castro Barbosa, Emerson, Alves, Tânia Maria Almeida, Kohlhoff, Markus, Jangola, Soraya Torres Gaze, Pires, Douglas Eduardo Valente, Figueiredo, Anna Carolina Cançado, Alves, Érica Alessandra Rocha, Calzavara-Silva, Carlos Eduardo, Sobral, Marcos, Kroon, Erna Geessien, Rosa, Luiz Henrique, Zani, Carlos Leomar, de Oliveira, Jaquelline Germano

“…The worldwide epidemics of diseases as dengue and Zika have triggered an intense effort to repurpose drugs and search for novel antivirals to treat patients as…”
Get full text

Anti- Leishmania compounds can be screened using Leishmania spp. expressing red fluorescence ( tdTomato ) by Cruz, Mariza Gabriela Faleiro de Moura Lodi, Santi, Ana Maria Murta, Morais-Teixeira, Eliane de, Caldeira, Alisson Samuel Portes, Siqueira, Ezequias Pessoa de, Oliveira, Edward, Alves, Tânia Maria de Almeida, Murta, Silvane Maria Fonseca

“…The main challenges associated with leishmaniasis chemotherapy are drug toxicity, the possible emergence of resistant parasites, and a limited choice of…”
Get full text

Adapting the roadmapping approach to science-intensive organizations: Lessons from a drug development program for neglected diseases by Freitas, Jonathan Simões, Bagno, Raoni Barros, Bertollo, Caryne Margotto, Alves, Tânia Maria de Almeida, Zani, Carlos Leomar, Cheng, Lin Chih, Gonçalves, Carlos Alberto

“…This paper discusses a roadmapping approach (RMA) adopted on a program on drug discovery and development for neglected diseases. This experience led to changes…”
Get full text

Thiosemicarbazone of lapachol acts on cell membrane in Paracoccidioides brasiliensis by de Sá, Nívea Pereira, Cisalpino, Patrícia Silva, Bertollo, Caryne Margotto, Santos, Patrícia Campi, Rosa, Carlos Augusto, de Souza, Daniele da Glória, Barbeira, Paulo Jorge Sanches, Alves, Tânia Maria de Almeida, Zani, Carlos Leomar, Johann, Susana

“…Abstract Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Latin American countries. Amphotericin B, sulfonamides, and azoles may be used…”
Get full text

Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood) by Cota, Betania Barros, Tunes, Luiza Guimarães, Maia, Daniela Nabak Bueno, Ramos, Jonas Pereira, Oliveira, Djalma Menezes de, Kohlhoff, Markus, Alves, Tânia Maria de Almeida, Souza-Fagundes, Elaine Maria, Campos, Fernanda Fraga, Zani, Carlos Leomar

“…BACKGROUND In a screen of extracts from plants and fungi to detect antileishmanial activity, we found that the ethyl acetate extract of the fungus Nectria…”
Get full text

Untargeted Liquid Chromatography-High-Resolution Mass Spectrometry Metabolomic Investigation Reveals Altered Lipid Content in Leishmania infantum Lacking Lipid Droplet Protein Kinase by Ribeiro, Juliana Martins, Canuto, Gisele André Baptista, Caldeira, Alisson Samuel Portes, de Siqueira, Ezequias Pessoa, Zani, Carlos Leomar, Murta, Silvane Maria Fonseca, de Almeida Alves, Tânia Maria

“…Leishmaniasis is a complex disease caused by different species of . To date, no vaccine for humans or ideal therapy has been developed owing to the limited…”
Get full text

Antifungal activity of trichothecenes from Fusarium sp. against clinical isolates of Paracoccidioides brasiliensis by Campos, Fernanda Fraga, Johann, Susana, Cota, Betania Barros, Alves, Tânia Maria Almeida, Rosa, Luiz Henrique, Caligiorne, Rachel Basques, Cisalpino, Patrícia Silva, Rosa, Carlos Augusto, Zani, Carlos Leomar

“…Summary Paracoccidioidomycosis (PCM), a human mycosis caused by the dimorphic fungus Paracoccidioides brasiliensis, is a serious public health problem in…”
Get full text

Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part I: Aspidosperma nitidum (Benth) used as a remedy to treat fever and malaria in the Amazon by Coutinho, Julia Penna, Aguiar, Anna Caroline Campos, dos Santos, Pierre Alexandre, Lima, Joaquim Corsino, Rocha, Maria Gabrielle Lima, Zani, Carlos Leomar, Alves, Tânia Maria Almeida, Santana, Antônio Euzébio Goulart, Pereira, Maria de Meneses, Krettli, Antoniana Ursine

“…Infusions of Aspidosperma nitidum (Apocynaceae) wood bark are used to treat fever and malaria in the Amazon Region. Several species of this family are known to…”
Get full text

The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives by Souza, Marina Azevêdo, Johann, Susana, Lima, Luciana Alves Rodrigues dos Santos, Campos, Fernanda Fraga, Mendes, Isolda Castro, Beraldo, Heloisa, Souza-Fagundes, Elaine Maria de, Cisalpino, Patrícia Silva, Rosa, Carlos Augusto, Alves, Tânia Maria de Almeida, de Sá, Nívea Pereira, Zani, Carlos Leomar

“…Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against…”
Get full text

Intra-specific phenotypic variations in Lantana camara leaves affect host selection by the gall maker Aceria lantanae by Dantas Moura, Maria Zabelê, Almeida Alves, Tânia Maria, Gonçalves Soares, Geraldo Luiz, Isaias, Rosy Mary dos Santos

“…Leaf galls induced by Aceria lantanae occur in distinct populations of Lantana camara, exclusively on individuals with red flowers. Anatomical, histochemical…”
Get full text

Leishmanicidal metabolites from Cochliobolus sp., an endophytic fungus isolated from Piptadenia adiantoides (Fabaceae) by Campos, Fernanda Fraga, Rosa, Luiz Henrique, Cota, Betania Barros, Caligiorne, Rachel Basques, Rabello, Ana Lúcia Teles, Alves, Tânia Maria Almeida, Rosa, Carlos Augusto, Zani, Carlos Leomar

“…Protozoan parasites belonging to genera Leishmania and Trypanosoma are the etiological agents of severe neglected tropical diseases (NTDs) that cause enormous…”
Get full text

Biological Screening of Brazilian Medicinal Plants by Alves, T M, Silva, A F, Brandão, M, Grandi, T S, Smânia, E, Smânia Júnior, A, Zani, C L

“…In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado") that could contain useful compounds for the control of tropical…”
Get full text

β-Carboline Glucoalkaloids from Psychotria cupularis and Evaluation of Their Antileishmanial Activity by Barreto, Ivan Martins, Moreira, Paulo Otávio Lourenço, de Macedo, Guadalupe Edilma Licona, Maia, Daniela Nabak Bueno, de Almeida Alves, Tânia Maria, de Oliveira, Djalma Menezes, Cota, Betania Barros

“…Purification of the crude ethanol extracts from leaves and stems of Psychotria cupularis (Müll.Arg.) Standl., Rubiaceae, resulted in the isolation of the known…”
Get full text

The analgesic and gastroprotective activities of the three fungal extracts and their possible correlation with the inhibition of the P2X7 receptor by Soares-Bezerra, Rômulo José, da Silva Ferreira, Natiele Carla, de Almeida Alves, Tânia Maria, Zani, Carlos Leomar, Rosa, Luiz Henrique, Calheiros, Andrea Surrage, de Souza, Cristiane Zanon, Miranda, Julliana Alves Azeredo, Lima-Quaresma, Kátia Regina Ferreira, Alves, Luiz Anastacio, da Silva Frutuoso, Válber

“…P2X7 is a purinergic receptor physiologically activated by extracellular ATP. Its activation induces proinflammatory responses, including cytokine release,…”
Get full text

Leishmanicidal activities of the extract from Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae by Siqueira, Ezequias Pessoa de, Souza-Fagundes, Elaine Maria de, Sobral, Marcos Eduardo Guerra, Alves, Tânia Maria de Almeida, Rabello, Ana, Zani, Carlos Leomar

“…Crude ethanolic extracts from Blepharocalyx salicifolius (Kunth) O. Berg, Myrtaceae, was fractioned by Gel Permeation Chromatography, using SephadexTM LH-20…”
Get full text

Trypanocidal Trixikingolides From Trixis Vauthieri by Sales Junior, Policarpo Ademar, Zani, Carlos Leomar, de Siqueira, Ezequias Pessoa, Kohlhoff, Markus, Marques, Fátima Regina, Caldeira, Alisson Samuel Portes, Cota, Betânia Barros, Maia, Daniela Nabak Bueno, Tunes, Luiza Guimarães, Murta, Silvane Maria Fonseca, Alves, Tânia Maria Almeida

“…Chagas disease is an illness caused by the protozoan parasite Trypanosoma cruzi. Only two drugs are available, with the drawback of low rate of cure in the…”
Get full text

Molecular phylogeny, diversity, symbiosis and discover of bioactive compounds of endophytic fungi associated with the medicinal Amazonian plant Carapa guianensis Aublet (Meliaceae) by Ferreira, Mariana Costa, Vieira, Mariana de Lourdes Almeida, Zani, Carlos Leomar, Alves, Tânia Maria de Almeida, Junior, Policarpo Ademar Sales, Murta, Silvane M.F., Romanha, Alvaro Jose, Gil, Laura Helena Vega Gonzales, Carvalho, Amanda Gomes de Oliveira, Zilli, Jerri Edson, Vital, Marcos José Salgado, Rosa, Carlos Augusto, Rosa, Luiz Henrique

“…We investigated the endophytic fungal community associated with the Amazonian medicinal plant Carapa guianensis and its potential for providing bioactive…”
Get full text