Neuropatia Periférica Induzida Pela Quimioterapia: Descrição de uma Técnica não Invasiva
Photobiomodulation (PBM) has been discussed as a therapy with great potential for controlling chemotherapy-induced peripheral neuropathy (CIPN). However, the results are still controversial and its real benefit has not yet been fully elucidated, which makes it difficult to develop clinical protocols...
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| Format: | Dissertation |
| Language: | Portuguese |
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ProQuest Dissertations & Theses
01-01-2023
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| Online Access: | Get full text |
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| Summary: | Photobiomodulation (PBM) has been discussed as a therapy with great potential for controlling chemotherapy-induced peripheral neuropathy (CIPN). However, the results are still controversial and its real benefit has not yet been fully elucidated, which makes it difficult to develop clinical protocols. The objective of this study was to analyze the influence of PBM on the treatment of CIPN.A systematic review was carried out by searching the data sources PubMed, Web of Science, LILACS and Scopus. Study eligibility criteria: studies in English and Spanish, without restriction on year of publication, that used the terms “Photobiomodulation therapy'', “Chemotherapy'' and “peripheral neuropathy'' and their synonyms. Study evaluation was carried out by JBI Levels of Evidence, Joanna Briggs Institute. Synthesis methods were carried out: according to the PRISMA flow diagram (Main Items for Reporting Systematic Reviews and Meta-Analyses).A total of 1,893 articles were found, after analysis, 4 articles were included, three of which were randomized clinical trials and the last was a prospective cohort pilot study, without a comparison group. Comprising the analysis of 163 participants who were diagnosed with cancer and were treated with chemotherapy. A favorable outcome to the PBM intervention was observed in all studies analyzed. The intervention protocols showed great variation in the chosen parameters, the weekly frequency of sessions varied between two to three sessions, lasting 4 to 6 weeks, and when carried out preventively, the duration was 12 to 18 weeks, depending on the regime. of chemotherapy. There was a reduction in neuropathic pain and paresthesia in the extremities, improvement in aerobic capacity, resistance and quality of life of the participants. There is the possibility of accelerating recovery from side effects induced by CIPN in breast cancer with the use of PBM preventively. The benefits extend between 10 to 12 weeks after the intervention. The evidence did not indicate better results from the use of PBM associated with physiotherapy. In conclusion, PBM as a therapeutic option for CIPN clinical manifestations has demonstrated positive results, both for prevention and for the treatment itself. Further studies with a larger number of participants, control of variables and a high level of evidence are necessary to clarify these clinical findings. |
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| ISBN: | 9798383781548 |