Search Results - "Alves, Isabel D."

The role of the lipid environment in the activity of G protein coupled receptors by Baccouch, Rim, Rascol, Estelle, Stoklosa, Kaja, Alves, Isabel D.

“…G protein coupled receptors (GPCRs) are a class of membrane proteins that sense extracellular signals ranging from light to odorants and small molecules and…”
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Improved Detection of Plasmon Waveguide Resonance Using Diverging Beam, Liquid Crystal Retarder, and Application to Lipid Orientation Determination by Isaacs, Sivan, Harté, Etienne, Alves, Isabel D, Abdulhalim, Ibrahim

“…Plasmon waveguide resonance (PWR) sensors exhibit narrow resonances at the two orthogonal polarizations, transverse electric (TE) and transverse magnetic (TM),…”
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Translocation and Endocytosis for Cell-penetrating Peptide Internalization by Jiao, Chen-Yu, Delaroche, Diane, Burlina, Fabienne, Alves, Isabel D., Chassaing, Gérard, Sagan, Sandrine

“…Cell-penetrating peptides (CPPs) share the property of cellular internalization. The question of how these peptides reach the cytoplasm of cells is still…”
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The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors by Boyé, Kevin, Pujol, Nadège, D Alves, Isabel, Chen, Ya-Ping, Daubon, Thomas, Lee, Yi-Zong, Dedieu, Stephane, Constantin, Marion, Bello, Lorenzo, Rossi, Marco, Bjerkvig, Rolf, Sue, Shih-Che, Bikfalvi, Andreas, Billottet, Clotilde

“…CXCR3 plays important roles in angiogenesis, inflammation, and cancer. However, the precise mechanism of regulation and activity in tumors is not well known…”
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Plasmon Waveguide Resonance: Principles, Applications and Historical Perspectives on Instrument Development by Rascol, Estelle, Villette, Sandrine, Harté, Etienne, Alves, Isabel D

“…Plasmon waveguide resonance (PWR) is a variant of surface plasmon resonance (SPR) that was invented about two decades ago at the University of Arizona. In…”
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Tryptophan within basic peptide sequences triggers glycosaminoglycan‐dependent endocytosis by Bechara, Chérine, Pallerla, Manjula, Zaltsman, Yefim, Burlina, Fabienne, Alves, Isabel D., Lequin, Olivier, Sagan, Sandrine

“…Deciphering the structural requirements and mechanisms for internalization of cell‐penetrating peptides (CPPs) is required to improve their delivery…”
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The role of tryptophans on the cellular uptake and membrane interaction of arginine-rich cell penetrating peptides by Jobin, Marie-Lise, Blanchet, Marine, Henry, Sarah, Chaignepain, Stéphane, Manigand, Claude, Castano, Sabine, Lecomte, Sophie, Burlina, Fabienne, Sagan, Sandrine, Alves, Isabel D.

“…Cell-penetrating peptides (CPP) are able to efficiently transport cargos across cell membranes without being cytotoxic to cells, thus present a great potential…”
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An original approach to measure ligand/receptor binding affinity in non-purified samples by Rascol, Estelle, Dufourquet, Anouk, Baccouch, Rim, Soule, Pierre, Alves, Isabel D.

“…Several biochemical and biophysical methods are available to determine ligand binding affinities between a biological target and its ligands, most of which…”
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Microfluidic diffusional sizing probes lipid nanodiscs formation by Azouz, Mehdi, Gonin, Mathilde, Fiedler, Sebastian, Faherty, Jonathan, Decossas, Marion, Cullin, Christophe, Villette, Sandrine, Lafleur, Michel, D. Alves, Isabel, Lecomte, Sophie, Ciaccafava, Alexandre

“…The biophysical characterisation of membrane proteins and their interactions with lipids in native membrane habitat remains a major challenge. Indeed,…”
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Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study by Alves, Isabel D, Bechara, Cherine, Walrant, Astrid, Zaltsman, Yefim, Jiao, Chen-Yu, Sagan, Sandrine

“…Penetratin is a positively charged cell-penetrating peptide (CPP) that has the ability to bind negatively charged membrane components, such as…”
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The enhanced membrane interaction and perturbation of a cell penetrating peptide in the presence of anionic lipids: Toward an understanding of its selectivity for cancer cells by Jobin, Marie-Lise, Bonnafous, Pierre, Temsamani, Hamza, Dole, François, Grélard, Axelle, Dufourc, Erick J., Alves, Isabel D.

“…Cell penetrating peptides (CPPs) are usually short, highly cationic peptides that are capable of crossing the cell membrane and transport cargos of varied size…”
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Biophysical Insight on the Membrane Insertion of an Arginine-Rich Cell-Penetrating Peptide by Jobin, Marie-Lise, Vamparys, Lydie, Deniau, Romain, Grélard, Axelle, Mackereth, Cameron D, Fuchs, Patrick F J, Alves, Isabel D

“…Cell-penetrating peptides (CPPs) are short peptides that can translocate and transport cargoes into the intracellular milieu by crossing biological membranes…”
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Direct translocation of cell-penetrating peptides in liposomes: A combined mass spectrometry quantification and fluorescence detection study by Walrant, Astrid, Matheron, Lucrèce, Cribier, Sophie, Chaignepain, Stéphane, Jobin, Marie-Lise, Sagan, Sandrine, Alves, Isabel D.

“…Cell-penetrating peptides (CPPs) can cross cell membranes in a receptor-independent manner. Two main routes for their cellular uptake have been proposed:…”
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Cell biology meets biophysics to unveil the different mechanisms of penetratin internalization in cells by Alves, Isabel D., Jiao, Chen-Yu, Aubry, Soline, Aussedat, Baptiste, Burlina, Fabienne, Chassaing, Gérard, Sagan, Sandrine

“…Although cell-penetrating peptides are widely used as molecular devices to cross membranes and transport molecules or nanoparticles inside cells, the…”
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Homeoproteins and homeoprotein-derived peptides: going in and out by Sagan, Sandrine, Burlina, Fabienne, Alves, Isabel D, Bechara, Chérine, Dupont, Edmond, Joliot, Alain

“…Since the initial evidence that antennapedia homeobox can cross cell membranes and internalize into cells, numerous peptides with similar translocation…”
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Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides by Chastel, Adrien, Worm, Dennis J., Alves, Isabel D., Vimont, Delphine, Petrel, Melina, Fernandez, Samantha, Garrigue, Philippe, Fernandez, Philippe, Hindié, Elif, Beck-Sickinger, Annette G., Morgat, Clément

“…Background Targeting G protein-coupled receptors on the surface of cancer cells with peptide ligands is a promising concept for the selective tumor delivery of…”
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Cellular uptake and biophysical properties of galactose and/or tryptophan containing cell-penetrating peptides by Lécorché, Pascaline, Walrant, Astrid, Burlina, Fabienne, Dutot, Laurence, Sagan, Sandrine, Mallet, Jean-Maurice, Desbat, Bernard, Chassaing, Gérard, Alves, Isabel D., Lavielle, Solange

“…Glycosylated cell penetrating peptides (CPPs) have been conjugated to a peptide cargo and the efficiency of cargo delivery into wild type Chinese hamster ovary…”
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Study of G‑Protein Coupled Receptor Signaling in Membrane Environment by Plasmon Waveguide Resonance by Alves, Isabel D, Lecomte, Sophie

“…Conspectus Here we describe an experimental technique, termed plasmon waveguide resonance (PWR) spectroscopy that enables the characterization of molecular…”
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Dendron-Functionalized Surface: Efficient Strategy for Enhancing the Capture of Microvesicles by Jiang, Jian-Qiao, Chanseau, Christel, Alves, Isabel D., Nlate, Sylvain, Durrieu, Marie-Christine

“…Microvesicles (MVs) are used by various types of cells in the human body for intercellular communication, making them biomarkers of great potential for the…”
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Direct Monitoring of GPCR Reconstitution and Ligand-Binding Activity by Plasmon Waveguide Resonance by Alves, Isabel D

“…The study of G-protein-coupled receptor (GPCR ) mechanisms of activation and signaling often the isolation, purification, and reconstitution of GPCRs in model…”
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