Search Results - "Alves, Guido W"
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Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson’s disease
Published in iScience (17-02-2023)“…Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired…”
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Cellular Proteostasis in Neurodegeneration
Published in Molecular neurobiology (01-05-2019)“…The term proteostasis reflects the fine-tuned balance of cellular protein levels, mediated through a vast network of biochemical pathways. This requires the…”
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Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies
Published in Frontiers in aging neuroscience (2016)“…Because of the complexity, heterogeneity, and the progressive nature of PD, such predictive and progression markers can only be identified in large cohorts and…”
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Journal Article