Search Results - "Alvariño, Rebeca"
-
1
Enniatins A1 and B1 Modulate Calcium Flux through Alternative Pathways beyond Mitochondria
Published in Journal of agricultural and food chemistry (03-07-2024)“…Enniatins (ENNs) A1 and B1, previously considered ionophores, are emerging mycotoxins with effects on Ca2+ homeostasis. However, their exact mechanism of…”
Get full text
Journal Article -
2
Simplified immunosuppressive and neuroprotective agents based on gracilin A
Published in Nature chemistry (01-04-2019)“…The architecture and bioactivity of natural products frequently serve as embarkation points for the exploration of biologically relevant chemical space. Total…”
Get full text
Journal Article -
3
Structures and Activities of Tiahuramides A–C, Cyclic Depsipeptides from a Tahitian Collection of the Marine Cyanobacterium Lyngbya majuscula
Published in Journal of natural products (Washington, D.C.) (22-06-2018)“…The structures of three new cyclic depsipeptides, tiahuramides A (1), B (2), and C (3), from a French Polynesian collection of the marine cyanobacterium…”
Get full text
Journal Article -
4
High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease
Published in Scientific reports (22-07-2019)“…Cyclophilins (Cyps) are ubiquitous proteins that belong to the immunophilins family consistently associated with inflammatory and cardiovascular diseases…”
Get full text
Journal Article -
5
Structure and biological evaluation of new cyclic and acyclic laxaphycin-A type peptides
Published in Bioorganic & medicinal chemistry (15-05-2019)“…[Display omitted] Five new laxaphycins were isolated and fully characterised from the bloom forming cyanobacteria Anabaena torulosa sampled from Moorea, French…”
Get full text
Journal Article -
6
Psammaplin A and Its Analogs Attenuate Oxidative Stress in Neuronal Cells through Peroxisome Proliferator-Activated Receptor γ Activation
Published in Journal of natural products (Washington, D.C.) (26-04-2024)“…Psammaplins are sulfur containing bromotyrosine alkaloids that have shown antitumor activity through the inhibition of class I histone deacetylases (HDACs)…”
Get full text
Journal Article -
7
Application of a multi-toxin detect method to analyze mycotoxins occurrence in plant-based beverages
Published in Food chemistry (15-02-2024)“…In recent years, plant-based beverages have gained popularity on the market due to environmental and ethical concerns, as well as milk intolerances and…”
Get full text
Journal Article -
8
Cyclophilin B serum levels present variations across the menstrual cycle
Published in Scientific reports (22-06-2023)“…Cyclophilins are a family of chaperones involved in inflammation and cell death. Cyclophilin B is released by inflammatory cells and acts through the receptor…”
Get full text
Journal Article -
9
Editorial: Natural products as drivers in drug development for neurodegenerative disorders, volume II
Published in Frontiers in pharmacology (17-11-2023)Get full text
Journal Article -
10
Occurrence of mycotoxins in total mixed ration of dairy farms in Portugal and carry-over to milk
Published in Food control (01-11-2024)“…This study aims to explore the presence of mycotoxins in total mixed rations (TMR) employed for feeding dairy cattle and their potential carry-over to milk. A…”
Get full text
Journal Article -
11
Magnetic nanostructured agents for the mitigation of mycotoxins and cyanotoxins in the food chain
Published in Food chemistry (30-10-2024)“…Natural toxins, such as mycotoxins and cyanotoxins, can contaminate food and feed, leading to toxicity in humans and animals. This study focused on using nine…”
Get full text
Journal Article -
12
Furanoditerpenes from Spongia (Spongia) tubulifera Display Mitochondrial-Mediated Neuroprotective Effects by Targeting Cyclophilin D
Published in ACS chemical neuroscience (17-08-2022)“…Neuroprotective properties of five previously described furanoditerpenes 1–5, isolated from Spongia (Spongia) tubulifera, were evaluated in an in vitro…”
Get full text
Journal Article -
13
Editorial: Natural products as drivers in drug development for neurodegenerative disorders
Published in Frontiers in pharmacology (04-08-2022)Get full text
Journal Article -
14
Gracilin A Derivatives Target Early Events in Alzheimer’s Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress
Published in ACS chemical neuroscience (18-09-2019)“…The search for compounds capable of targeting early pathological changes of Alzheimer̀s disease (AD), such as oxidative stress and neuroinflammation, is an…”
Get full text
Journal Article -
15
Extracellular cyclophilins A and C induce dysfunction of pancreatic microendothelial cells
Published in Frontiers in physiology (05-10-2022)“…Extracellular cyclophilins (eCyps) A and B are chemotactic mediators in several illnesses in which inflammation plays an important role such as diabetes and…”
Get full text
Journal Article -
16
Salen‑manganese complexes for controlling ROS damage: Neuroprotective effects, antioxidant activity and kinetic studies
Published in Journal of inorganic biochemistry (01-02-2020)“…A new manganese(III) complex [MnL1(DCA)(H2O)](H2O),1 [H2L1 is the chelating ligand N,N′-bis(2-hydroxy-3-methoxybenzylidene)-1,2-diaminopropane, and DCA is…”
Get full text
Journal Article -
17
Combined Effect of Caspase-Dependent and Caspase-Independent Apoptosis in the Anticancer Activity of Gold Complexes with Phosphine and Benzimidazole Derivatives
Published in Pharmaceuticals (Basel, Switzerland) (24-12-2020)“…Since the potential anticancer activity of auranofin was discovered, gold compounds have attracted interest with a view to developing anticancer agents that…”
Get full text
Journal Article -
18
First description of adenosine production by Gnomoniopsis smithogilvyi, causal agent of chestnut brown rot
Published in World journal of microbiology & biotechnology (01-05-2024)“…Gnomoniopsis smithogilvyi ( Gnomoniaceae , Diaporthales ) is the main causal agent of chestnut brown rot on sweet chestnut worldwide. The rotting of nuts leads…”
Get full text
Journal Article -
19
Understanding the Factors That Influence the Antioxidant Activity of Manganosalen Complexes with Neuroprotective Effects
Published in Antioxidants (22-02-2024)“…Manganosalen complexes are a class of catalytic antioxidants with beneficial effects against different neurological disorders according to various in vitro and…”
Get full text
Journal Article -
20
In Vitro Testing of Lung Carcinogenicity for an In Silico-Identified Cluster of Mycotoxins
Published in Exposure and health (01-08-2024)“…Occurrence of emerging mycotoxins in food and feed is reported worldwide, but studies on their toxic effects are still limited. Our previous study based on in…”
Get full text
Journal Article