Search Results - "Alvarez, Ofelia A"

Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease by Ataga, Kenneth I, Kutlar, Abdullah, Kanter, Julie, Liles, Darla, Cancado, Rodolfo, Friedrisch, João, Guthrie, Troy H, Knight-Madden, Jennifer, Alvarez, Ofelia A, Gordeuk, Victor R, Gualandro, Sandra, Colella, Marina P, Smith, Wally R, Rollins, Scott A, Stocker, Jonathan W, Rother, Russell P

“…In this yearlong trial involving patients with sickle cell disease, crizanlizumab, an antibody to P-selectin, was associated with a 45% lower rate of pain…”
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Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia by Schaefer, Beverly A, Flanagan, Jonathan M, Alvarez, Ofelia A, Nelson, Stephen C, Aygun, Banu, Nottage, Kerri A, George, Alex, Roberts, Carla W, Piccone, Connie M, Howard, Thad A, Davis, Barry R, Ware, Russell E

“…Discovery and validation of genetic variants that influence disease severity in children with sickle cell anemia (SCA) could lead to early identification of…”
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Renal Function in Infants with Sickle Cell Anemia: Baseline Data from the BABY HUG Trial by Ware, Russell E., MD, PhD, Rees, Renee C., PhD, Sarnaik, Sharada A., MD, Iyer, Rathi V., MD, Alvarez, Ofelia A., MD, Casella, James F., MD, Shulkin, Barry L., MD, Shalaby-Rana, Eglal, MD, Strife, C. Frederic, MD, Miller, John H., MD, Lane, Peter A., MD, Wang, Winfred C., MD, Miller, Scott T., MD

“…Objectives To examine the feasibility and accuracy of glomerular filtration rate (GFR) measurements in infants with sickle cell anemia (SCA). Study design The…”
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Double-blind, randomized, multicenter phase 2 study of SC411 in children with sickle cell disease (SCOT trial) by Daak, Ahmed A., Dampier, Carlton D., Fuh, Beng, Kanter, Julie, Alvarez, Ofelia A., Black, L. Vandy, McNaull, Melissa A., Callaghan, Michael U., George, Alex, Neumayr, Lynne, Hilliard, Lee M., Sancilio, Fredrick, Rabinowicz, Adrian L., Heeney, Matthew M.

“…Blood cell membranes in sickle cell disease (SCD) have low docosahexaenoic acid (DHA). DHA treatment reduces sickle cell crisis (SCC) rate and ameliorates the…”
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Newborn Screening for Sickle Cell Disease Using Point-of-Care Testing in Low-Income Setting by Alvarez, Ofelia A, Hustace, Tally, Voltaire, Mimose, Mantero, Alejandro, Liberus, Ulrick, Saint Fleur, Rony

“…Newborn screening provides early diagnosis for children with sickle cell disease (SCD), reducing disease-related mortality. We hypothesized that rapid…”
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Effect of crizanlizumab on pain crises in subgroups of patients with sickle cell disease: A SUSTAIN study analysis by Kutlar, Abdullah, Kanter, Julie, Liles, Darla K., Alvarez, Ofelia A., Cançado, Rodolfo D., Friedrisch, João R., Knight‐Madden, Jennifer M., Bruederle, Andreas, Shi, Michael, Zhu, Zewen, Ataga, Kenneth I.

“…The cell adhesion molecule P‐selectin plays a key role in the pathogenesis of a vaso‐occlusive crisis (VOC) in patients with sickle cell disease (SCD). In the…”
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Consensus definition of essential, optimal, and suggested components of a pediatric sickle cell disease center by Hulbert, Monica L., Manwani, Deepa, Meier, Emily Riehm, Alvarez, Ofelia A., Brown, R. Clark, Callaghan, Michael U., Campbell, Andrew D., Coates, Thomas D., Frei‐Jones, Melissa J., Hankins, Jane S., Heeney, Matthew M., Hsu, Lewis L., Lebensburger, Jeffrey D., Quinn, Charles T., Shah, Nirmish, Smith‐Whitley, Kim, Thornburg, Courtney, Kanter, Julie

“…Sickle cell disease (SCD) requires coordinated, specialized medical care for optimal outcomes. There are no United States (US) guidelines that define a…”
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Implementation of hospital-based sickle cell newborn screening and follow-up programs in Haiti by Alvarez, Ofelia A, St Victor Dély, Nora, Paul Hanna, Michele, Saint Fleur, Rony, Cetoute, Marie, Metalonis, Sarah, Hustace, Tally, Brown, Eric C, Marcelin, Louis Herns, Muscadin, Emanise, Eveillard, Ronald, Lerebours, Emmeline

“…One in 120 children are born with sickle cell disease (SCD) in Haiti. However, health care challenges include isolated newborn screening (NBS) activities and…”
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Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury by Adamkiewicz, Thomas V., Abboud, Miguel R., Paley, Carole, Olivieri, Nancy, Kirby-Allen, Melanie, Vichinsky, Elliott, Casella, James F., Alvarez, Ofelia A., Barredo, Julio C., Lee, Margaret T., Iyer, Rathi V., Kutlar, Abdullah, McKie, Kathleen M., McKie, Virgil, Odo, Nadine, Gee, Beatrice, Kwiatkowski, Janet L., Woods, Gerald M., Coates, Thomas, Wang, Winfred, Adams, Robert J.

“…Chronic blood transfusion is increasingly indicated in patients with sickle cell disease. Measuring resulting iron overload remains a challenge. Children…”
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Thoracic lymphangiomatosis in a child by Alvarez, Ofelia A, Kjellin, Ingrid, Zuppan, Craig W

“…An 8-year-old boy who presented with a mediastinal mass, pulmonary infiltrates, and disseminated intravascular coagulation was diagnosed with…”
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Renal Medullary Carcinoma: The Kidney Cancer That Affects Individuals With Sickle Cell Trait and Disease by Alvarez, Ofelia A

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Primary renal botryoid rhabdomyosarcoma: diagnosis and outcome by Sola, Juan E, Cova, Deborah, Casillas, Javier, Alvarez, Ofelia A, Qualman, Stephen, Rodriguez, Maria M

“…Abstract Primary renal rhabdomyosarcoma is a rare entity. We report on a pediatric patient who, despite having multiple metastases to the lung on presentation,…”
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Wilms' tumor, pancreatic islet cell carcinoma, and pheochromocytoma in a child by Sola, Juan E, Gutierrez, Juan C, Thompson, William R, Alvarez, Ofelia A, Casillas, Javier, Rodriguez, Maria M

“…Abstract We present the first case of Wilms' tumor, pancreatic islet cell carcinoma, and pheochromocytoma affecting the same individual. This case underscores…”
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Development of a Low-Cost Electrical Impedance-Based Microflow Cytometer by Dieujuste, Darryl, Liu, Jia, Du, E., Alvarez, Ofelia A.

“…Sickle Cell Disease (SCD) is a genetic condition caused by a mutated hemoglobin molecule (HbS) found in red blood cells (RBCs). HbS polymerizes in low oxygen…”
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Successful Use of Therapeutic Plasma Exchange Following Red Blood Cell Exchange for Severe Acute Chest Syndrome: A Single Institution Experience by Kronenfeld, Rachel S., Nunez, Veronica, Duque Cuartas, Miriam, El Beayni, Nancy, Harrington, Thomas J., Wu, Yanyun, Alvarez, Ofelia A.

“…Introduction: Severe acute chest syndrome (ACS) is a potentially fatal complication of sickle cell disease (SCD) that can progress to multiorgan failure…”
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Real-World Effectiveness of Voxelotor for the Treatment of Sickle Cell Disease: Group and Pediatric Subgroup Analyses of Effects on Transfusions, Vaso-Occlusive Crises, and Hospitalizations by Shah, Nirmish, Lipato, Thokozeni, Delea, Thomas E., Lonshteyn, Alexander, Weycker, Derek, Nguyen, Andy, Beaubrun, Anne, Alvarez, Ofelia A.

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Optimal Hemoglobin Level for Pediatric Sickle Cell Patients Who Undergo Adenotonsillectomy by Hu, Zhongbo, Chang, Simone Megan, Younis, Ramzi, Alvarez, Ofelia A.

“…Background:The prevalence of obstructive sleep apnea syndrome (OSA) in children with sickle cell disease (SCD) is higher than in the general pediatric…”
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Real-World Experience of Voxelotor for the Management of Complications in Sickle Cell Disease by Shah, Nirmish, Lipato, Thokozeni, Alvarez, Ofelia A., Delea, Thomas, Lonshteyn, Alexander, Weycker, Derek, Nguyen, Andy, Beaubrun, Anne, Agodoa, Irene

“…Background: Sickle cell disease (SCD) is an inherited systemic disorder characterized by chronic hemolytic anemia and recurrent vaso-occlusion, which can lead…”
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Comparison of Clinical Evolution of Children with Sickle Cell Disease before and after Treatment with Hydroxyurea at Saint Damien Hospital, Tabarre-Haiti,2013-2018 by Dély, Nora St Victor, Alvarez, Ofelia A., Dor, Vanessa J, Lerebours, Emmeline

“…INTRODUCTION Sickle cell disease (SCD), an autosomal recessive hemoglobinopathy, is associated with a high morbidity and mortality rate, especially in low…”
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Real-World Implementation of Sickle Cell Transition Programs As Part of a State Quality Improvement Network by Alvarez, Ofelia A., Gann, Carrie, Ringdahl, Debbie, Bansal, Manisha, Alvarez-Nunez, Farranaz, Slayton, William, Kashif, Reema, Wynn, Tung, Bradley, Elizabeth, Diener, Kathryn, Rivers, Katrina, Buchman, Sherry, Chatfield, Angela, Heldreth, Monica, Crowe, Virginia, Butts-Dion, Sue

“…The Florida Department of Health's Division of Children's Medical Services administers, with facilitation service from the National Institute for Children's…”
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