Search Results - "Alvarez, Marcus A."
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TGF-β Alters the Proportion of Infiltrating Immune Cells in a Pancreatic Ductal Adenocarcinoma
Published in Journal of gastrointestinal surgery (2022)“…Purpose Immunotherapy, such as checkpoint inhibitors against anti-programmed death-ligand 1 (PD-L1), has not been successful in treating patients with…”
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TGF-β Inhibitors in Metastatic Pancreatic Ductal Adenocarcinoma
Published in Journal of gastrointestinal cancer (15-06-2019)“…Background Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancerrelated mortality in the USA, and the overall incidence of the disease…”
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Traveling for Pancreatic Cancer Care Is Worth the Trip
Published in The American surgeon (01-04-2021)“…Centralized care for patients with pancreatic cancer is associated with longer survival. We hypothesized that increased travel distance from home is associated…”
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Role of TGF-β in pancreatic ductal adenocarcinoma progression and PD-L1 expression
Published in Cellular oncology (Dordrecht) (01-06-2021)“…Purpose The transforming growth factor-beta (TGF-β) pathway plays a paradoxical, context-dependent role in pancreatic ductal adenocarcinoma (PDAC): a…”
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Abstract C18: TGF-beta blockade paradoxically activates non-SMAD signaling
Published in Cancer research (Chicago, Ill.) (15-12-2019)“…Transforming growth factor-beta (TGF-B) activates a receptor leading to a critical signaling cascade in pancreatic ductal adenocarcinoma (PDAC) that results in…”
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890 TGF-β RECEPTOR INHIBITION INCREASES PD-L1 EXPRESSION IN PANCREATIC CANCER
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2020)Get full text
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The effect of TGF-β on PD-L1 expression on PDAC TAMs
Published in Journal of clinical oncology (01-02-2020)“…Abstract only 764 Background: Pancreatic Ductal Adenocarcinoma (PDAC) has less than a 10% five year survival and will become the second leading cause of US…”
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Abstract 2374: Non-canonical TGF-beta signaling modulates pancreatic ductal adenocarcinoma progression
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Introduction: While the genomic and proteomic characterization of pancreatic ductal adenocarcinoma (PDAC) is extraordinarily complex, the transforming growth…”
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High-income is a stronger predictor than race in understanding disparate survival outcomes in PDAC
Published in Journal of clinical oncology (01-02-2019)“…Abstract only 241 Background: Patients with pancreatic ductal adenocarcinoma (PDAC) from low income and minority racial groups have a lower reported long-term…”
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Chemoresistance in Pancreatic Carcinoma Induces PD-L1 and CD44 Expression
Published in Journal of the American College of Surgeons (01-10-2019)Get full text
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