Search Results - "Alvarez, Jacqueline G."

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis by Mihaylova, Maria M., Vasquez, Debbie S., Ravnskjaer, Kim, Denechaud, Pierre-Damien, Yu, Ruth T., Alvarez, Jacqueline G., Downes, Michael, Evans, Ronald M., Montminy, Marc, Shaw, Reuben J.

“…Class IIa histone deacetylases (HDACs) are signal-dependent modulators of transcription with established roles in muscle differentiation and neuronal survival…”
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AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation by Lamia, Katja A, Sachdeva, Uma M, DiTacchio, Luciano, Williams, Elliot C, Alvarez, Jacqueline G, Egan, Daniel F, Vasquez, Debbie S, Juguilon, Henry, Panda, Satchidananda, Shaw, Reuben J, Thompson, Craig B, Evans, Ronald M

“…Circadian clocks coordinate behavioral and physiological processes with daily light-dark cycles by driving rhythmic transcription of thousands of genes…”
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Benefit of Farnesoid X Receptor Inhibition in Obstructive Cholestasis by Stedman, Catherine, Liddle, Christopher, Coulter, Sally, Sonoda, Junichiro, Alvarez, Jacqueline G., Evans, Ronald M., Downes, Michael

“…The nuclear hormone receptors farnesoid X receptor (FXR) and pregnane X receptor have been implicated in regulating bile acid, lipid, carbohydrate, and…”
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Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Ameliorate Cholestatic Liver Injury by Catherine A. M. Stedman, Liddle, Christopher, Coulter, Sally A., Sonoda, Junichiro, Jacqueline G. A. Alvarez, Moore, David D., Evans, Ronald M., Downes, Michael

“…Cholestasis is associated with accumulation of bile acids and lipids, and liver injury. The constitutive androstane receptor (CAR) and pregnane X receptor…”
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FGF1 and insulin control lipolysis by convergent pathways by Sancar, Gencer, Liu, Sihao, Gasser, Emanuel, Alvarez, Jacqueline G., Moutos, Christopher, Kim, Kyeongkyu, van Zutphen, Tim, Wang, Yuhao, Huddy, Timothy F., Ross, Brittany, Dai, Yang, Zepeda, David, Collins, Brett, Tilley, Emma, Kolar, Matthew J., Yu, Ruth T., Atkins, Annette R., van Dijk, Theo H., Saghatelian, Alan, Jonker, Johan W., Downes, Michael, Evans, Ronald M.

“…Inexorable increases in insulin resistance, lipolysis, and hepatic glucose production (HGP) are hallmarks of type 2 diabetes. Previously, we showed that…”
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Identification of a Nuclear Domain with Deacetylase Activity by Downes, Michael, Ordentlich, Peter, Kao, Hung-Ying, Jacqueline G. A. Alvarez, Evans, Ronald M.

“…Here, we describe the identification and characterization of a nuclear body (matrix-associated deacetylase body) whose formation and integrity depend on…”
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A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR by Downes, Michael, Verdecia, Mark A., Roecker, A.J., Hughes, Robert, Hogenesch, John B., Kast-Woelbern, Heidi R., Bowman, Marianne E., Ferrer, Jean-Luc, Anisfeld, Andrew M., Edwards, Peter A., Rosenfeld, John M., Alvarez, Jacqueline G.A., Noel, Joseph P., Nicolaou, K.C, Evans, Ronald M.

“…The farnesoid X receptor (FXR) functions as a bile acid (BA) sensor coordinating cholesterol metabolism, lipid homeostasis, and absorption of dietary fats and…”
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Activators of the nuclear receptor PPARγ enhance colon polyp formation by Evans, Ronald M, Saez, Enrique, Tontonoz, Peter, Nelson, Michael C, Alvarez, Jacqueline G.A, U, Tze Ming, Baird, Stephen M, Thomazy, Vilmos A

“…A high-fat diet increases the risk of colon, breast and prostate cancer. The molecular mechanism by which dietary lipids promote tumorigenesis is unknown…”
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