Search Results - "Alvarez, Frances Joan D."
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CryoEM structure of the super-constricted two-start dynamin 1 filament
Published in Nature communications (13-09-2021)“…Dynamin belongs to the large GTPase superfamily, and mediates the fission of vesicles during endocytosis. Dynamin molecules are recruited to the neck of…”
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Structural Insight into HIV-1 Restriction by MxB
Published in Cell host & microbe (12-11-2014)“…The myxovirus resistance (Mx) proteins are interferon-induced dynamin GTPases that can inhibit a variety of viruses. Recently, MxB, but not MxA, was shown to…”
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3
Functional Reconstitution of an ABC Transporter in Nanodiscs for Use in Electron Paramagnetic Resonance Spectroscopy
Published in Journal of the American Chemical Society (21-07-2010)“…Electron paramagnetic resonance (EPR) spectroscopy is a powerful biophysical technique for study of the structural dynamics of membrane proteins. Many of these…”
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Dynamics of α-helical subdomain rotation in the intact maltose ATP-binding cassette transporter
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2010)“…ATP-binding cassette (ABC) transporters are powered by a nucleotide-binding domain dimer that opens and closes during cycles of ATP hydrolysis. These domains…”
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5
Purification and Characterization of MxB
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…MxB/Mx2 is an interferon-induced dynamin-like GTPase, which restricts a number of life-threatening viruses. Because of its N-terminal region, predicted to be…”
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Deep learning-driven super-resolution in Raman hyperspectral imaging: Efficient high-resolution reconstruction from low-resolution data
Published in Applied physics letters (11-11-2024)“…Deep learning (DL) has become an indispensable tool in hyperspectral data analysis, automatically extracting valuable features from complex, high-dimensional…”
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Full engagement of liganded maltose‐binding protein stabilizes a semi‐open ATP‐binding cassette dimer in the maltose transporter
Published in Molecular microbiology (01-12-2015)“…Summary MalFGK2 is an ATP‐binding cassette (ABC) transporter that mediates the uptake of maltose/maltodextrins into Escherichia coli. A periplasmic…”
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Cryoem Structure of the Full Length Dynamin-Like MxB at 4.6 Å Resolution
Published in Biophysical journal (03-02-2017)Get full text
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CryoEM structure of dynamin-like MxB in assembly
Published in Acta crystallographica. Section A, Foundations and advances (26-05-2017)“…Abstract only…”
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10
Molecular Insights into the Signaling Mechanism of the Histidine Kinase CheA within an Intact Bacterial Chemosensory Array
Published in Biophysical journal (27-01-2015)Get full text
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Cryo-Electron Tomography and Computer Simulations Reveal Distinct CheA Kinase Conformation in Bacterial Chemotaxis Signaling Receptor Complex
Published in Biophysical journal (27-01-2015)Get full text
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12
Structural studies of Dnm1/Drp1 provide mechanistic insight into mitochondrial fission
Published in Mitochondrion (01-09-2012)Get full text
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13
Dynamics of [alpha]-helical subdomain rotation in the intact maltose ATP-binding cassette transporter
Published in Proceedings of the National Academy of Sciences - PNAS (23-11-2010)“…ATP-binding cassette (ABC) transporters are powered by a nucleotide-binding domain dimer that opens and closes during cycles of ATP hydrolysis. These domains…”
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14
Conformational dynamics of the Escherichia coli maltose transporter
Published 01-01-2011“…The maltose transporter in Escherichia coli is composed of MalF and MalG, which form a transmembrane pore for passage of maltose, and of MalK2, which binds and…”
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