Search Results - "Alvarez, Diego E."

Cell-to-Cell Transmission Is the Main Mechanism Supporting Bovine Viral Diarrhea Virus Spread in Cell Culture by Merwaiss, Fernando, Czibener, Cecilia, Alvarez, Diego E

“…After initiation of an infective cycle, spread of virus infection can occur in two fundamentally different ways: (i) viral particles can be released into the…”
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Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina by Ojeda, Diego S, Gonzalez Lopez Ledesma, María Mora, Pallarés, Horacio M, Costa Navarro, Guadalupe S, Sanchez, Lautaro, Perazzi, Beatriz, Villordo, Sergio M, Alvarez, Diego E, Echavarria, Marcela, Oguntuyo, Kasopefoluwa Y, Stevens, Christian S, Lee, Benhur, Carradori, Jorge, Caramelo, Julio J, Yanovsky, Marcelo J, Gamarnik, Andrea V

“…We report the emergency development and application of a robust serologic test to evaluate acute and convalescent antibody responses to SARS-CoV-2 in…”
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Dengue virus preferentially uses human and mosquito non-optimal codons by Castellano, Luciana A, McNamara, Ryan J, Pallarés, Horacio M, Gamarnik, Andrea V, Alvarez, Diego E, Bazzini, Ariel A

“…Codon optimality refers to the effect that codon composition has on messenger RNA (mRNA) stability and translation level and implies that synonymous codons are…”
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RNA recombination at Chikungunya virus 3'UTR as an evolutionary mechanism that provides adaptability by Filomatori, Claudia V, Bardossy, Eugenia S, Merwaiss, Fernando, Suzuki, Yasutsugu, Henrion, Annabelle, Saleh, María Carla, Alvarez, Diego E

“…The potential of RNA viruses to adapt to new environments relies on their ability to introduce changes in their genomes, which has resulted in the recent…”
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The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility by Alvarez, Diego E, Agaisse, Hervé

“…Vaccinia virus dissemination relies on the N-WASP-ARP2/3 pathway, which mediates actin tail formation underneath cell-associated extracellular viruses (CEVs)…”
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Zika virus non-coding RNAs antagonize antiviral responses by PKR-mediated translational arrest by Pallarés, Horacio M, González López Ledesma, María Mora, Oviedo-Rouco, Santiago, Castellano, Luciana A, Costa Navarro, Guadalupe S, Fernández-Alvarez, Ana J, D’Andreiz, María Josefina, Aldas-Bulos, Victor Daniel, Alvarez, Diego E, Bazzini, Ariel A, Gamarnik, Andrea V

“…Abstract Zika virus (ZIKV) is an emerging mosquito-borne flavivirus that causes severe outbreaks in human populations. ZIKV infection leads to the accumulation…”
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A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice by Coria, Lorena M, Saposnik, Lucas M, Pueblas Castro, Celeste, Castro, Eliana F, Bruno, Laura A, Stone, William B, Pérez, Paula S, Darriba, Maria Laura, Chemes, Lucia B, Alcain, Julieta, Mazzitelli, Ignacio, Varese, Augusto, Salvatori, Melina, Auguste, Albert J, Álvarez, Diego E, Pasquevich, Karina A, Cassataro, Juliana

“…In this work, we evaluated recombinant receptor binding domain (RBD)-based vaccine formulation prototypes with potential for further clinical development. We…”
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A 5' RNA element promotes dengue virus RNA synthesis on a circular genome by Filomatori, Claudia V, Lodeiro, Maria F, Alvarez, Diego E, Samsa, Marcelo M, Pietrasanta, Lía, Gamarnik, Andrea V

“…The mechanisms of RNA replication of plus-strand RNA viruses are still unclear. Here, we identified the first promoter element for RNA synthesis described in a…”
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Functional analysis of dengue virus cyclization sequences located at the 5′ and 3′UTRs by Alvarez, Diego E, Filomatori, Claudia V, Gamarnik, Andrea V

“…Abstract Flavivirus RNA replication involves cyclization of the viral genome. A model for this process includes a promoter element at the 5′ end of the genome…”
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Long-Range RNA-RNA Interactions Circularize the Dengue Virus Genome by ALVAREZ, Diego E, LODEIRO, Maria F, LUDUENA, Silvio J, PIETRASANTA, Lia I, GAMARNIK, Andrea V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A β-Hairpin Motif in the Envelope Protein E2 Mediates Receptor Binding of Bovine Viral Diarrhea Virus by Merwaiss, Fernando, Pascual, María José, Pomilio, María Trinidad, Lopez, María Gabriela, Taboga, Oscar A., Alvarez, Diego E.

“…Pestivirus envelope protein E2 is crucial to virus infection and accomplishes virus-receptor interaction during entry. However, mapping of E2 residues…”
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Discovery of Novel Bovine Viral Diarrhea Inhibitors Using Structure-Based Virtual Screening on the Envelope Protein E2 by Bollini, Mariela, Leal, Emilse S, Adler, Natalia S, Aucar, María G, Fernández, Gabriela A, Pascual, María J, Merwaiss, Fernando, Alvarez, Diego E, Cavasotto, Claudio N

“…Bovine viral diarrhea virus (BVDV) is a member of the genus Pestivirus within the family Flaviviridae. BVDV causes both acute and persistent infections in…”
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The Metalloprotease Mpl Supports Listeria monocytogenes Dissemination through Resolution of Membrane Protrusions into Vacuoles by Alvarez, Diego E, Agaisse, Hervé

“…Listeria monocytogenes is an intracellular pathogen that disseminates within the intestinal epithelium through acquisition of actin-based motility and…”
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New Highly Selective Antivirals for Chikungunya Virus identified from the Screening of a Drug-Like Compound Library by Castro, Eliana F., Álvarez, Diego E.

“…Chikungunya fever is a mosquito-borne disease caused by Chikungunya virus (CHIKV). Treatment of CHIKV infections is currently supportive and does not limit…”
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Chikungunya Virus Replication Rate Determines the Capacity of Crossing Tissue Barriers in Mosquitoes by Merwaiss, Fernando, Filomatori, Claudia V, Susuki, Yasutsugu, Bardossy, Eugenia S, Alvarez, Diego E, Saleh, María-Carla

“…Chikungunya virus (CHIKV) is a reemerging and rapidly spreading pathogen transmitted by mosquitoes. The emergence of new epidemic variants of the virus is…”
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Molecular basis of RNA recombination in the 3′UTR of chikungunya virus genome by Bardossy, Eugenia S, Volpe, Sebastiano, Suzuki, Yasutsugu, Merwaiss, Fernando, Faraj, Santiago, Montes, Mónica, Saleh, Maria-Carla, Alvarez, Diego E, Filomatori, Claudia V

“…Abstract Chikungunya virus (CHIKV) is a rapidly spreading re-emergent virus transmitted from mosquitoes to humans. The emergence of epidemic variants has been…”
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Impact of alphavirus 3’UTR plasticity on mosquito transmission by Filomatori, Claudia V., Merwaiss, Fernando, Bardossy, Eugenia S., Alvarez, Diego E.

“…[Display omitted] •RNA repeated sequence elements are a common trait in the 3’UTR of arboviruses.•Alphavirus sequence duplications assure high viral fitness in…”
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A balance between circular and linear forms of the dengue virus genome is crucial for viral replication by Villordo, Sergio M, Alvarez, Diego E, Gamarnik, Andrea V

“…The plasticity of viral plus strand RNA genomes is fundamental for the multiple functions of these molecules. Local and long-range RNA-RNA interactions provide…”
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Changes in the chikungunya virus E1 glycoprotein domain II and hinge influence E2 conformation, infectivity, and virus-receptor interactions by Thannickal, Sara A, Battini, Leandro, Spector, Sophie N, Noval, Maria G, Álvarez, Diego E, Stapleford, Kenneth A

“…In a previous study to understand how the chikungunya virus (CHIKV) E1 glycoprotein β-strand c functions, we identified several attenuating variants at E1…”
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RNA Sequences and Structures Required for the Recruitment and Activity of the Dengue Virus Polymerase by Filomatori, Claudia V., Iglesias, Nestor G., Villordo, Sergio M., Alvarez, Diego E., Gamarnik, Andrea V.

“…Dengue virus RNA-dependent RNA polymerase specifically binds to the viral genome by interacting with a promoter element known as stem-loop A (SLA). Although a…”
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