Search Results - "Alvarez, Delia"
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Modulation of Circulating Protein Biomarkers in Cancer Patients Receiving Bevacizumab and the Anti-Endoglin Antibody, TRC105
Published in Molecular cancer therapeutics (01-10-2018)“…TRC105 is an anti-endoglin antibody currently being tested in combination with VEGF inhibitors. In the phase Ib trial, 38 patients were treated with both…”
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2
Shedding light on the mitochondrial matrix through a functional membrane transporter
Published in Chemical science (Cambridge) (2020)“…The first fluorescent probes that are actively channeled into the mitochondrial matrix by a specific mitochondrial membrane transporter in living cells have…”
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3
A general modular approach for the solubility tagging of BODIPY dyes
Published in Dyes and pigments (01-11-2019)“…We describe a general and practical strategy for the direct one-step incorporation of a tunable solubility module at the boron atom of F-BODIPY dyes. The…”
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4
A Phase I First-in-Human Study of TRC105 (Anti-Endoglin Antibody) in Patients with Advanced Cancer
Published in Clinical cancer research (01-09-2012)“…TRC105 is a chimeric IgG1 monoclonal antibody that binds CD105 (endoglin). This first-in-human, phase I, open-label study assessed safety, pharmacokinetics,…”
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Moodle: Aprovechamiento de herramientas en el centro universitario del norte
Published in Boletín Redipe (01-11-2023)“…El Centro Universitario del Norte (CUNorte) de la Universidad de Guadalajara (U. de G.), tiene una modalidad educativa presencial con apoyo en las tecnologías…”
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6
Comparison of vis-NIR spectral signatures of soils cultivated with sugarcane (Sacharum sp.) in the Villa Clara province
Published in Centro agrícola (01-10-2019)“…The objective of this research was to compare the spectral signature of two soil types, Cambisol and Vertisol, cultivated with sugarcane in the Villa Clara…”
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KRYSTAL-12: A randomized phase 3 study of adagrasib (MRTX849) versus docetaxel in patients (pts) with previously treated non-small-cell lung cancer (NSCLC) with KRAS G12C mutation
Published in Journal of clinical oncology (20-05-2021)“…Abstract only TPS9129 Background: Despite significant advances in chemotherapy and immunotherapy for advanced NSCLC, the majority of pts ultimately develop…”
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Cellulolytic fungi populations in stubble and soil as affected by agricultural management practices
Published in Biological agriculture & horticulture (2005)“…The aim of this study was to evaluate the effects of different agricultural management practices on the dynamics of cellulolytic fungi populations. The…”
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An open-label phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) with bevacizumab in patients with advanced cancer
Published in Clinical cancer research (01-12-2014)“…Endoglin, an endothelial cell membrane receptor expressed on angiogenic tumor vessels, is essential for angiogenesis and upregulated in the setting of VEGF…”
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10
La educación no formal: una herramienta importante para la formación del estudiante de medicina
Published in Ars medica (Santiago, Chile) (14-02-2019)“…El impacto de la educación desde sus diferentes aristas es invaluable, especialmente en el ámbito universitario y resaltado en la carrera de medicina, por lo…”
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11
Phase II study of sitravatinib in combination with nivolumab in patients with advanced or metastatic urothelial carcinoma (UC) after checkpoint inhibitor therapy (CIT)
Published in Journal of clinical oncology (01-03-2019)“…Abstract only TPS498 Background: Combination therapy with agents targeting molecular and cellular mechanisms of CIT resistance is a rational approach to…”
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Phase III trial of sitravatinib plus nivolumab vs. docetaxel for treatment of NSCLC after platinum-based chemotherapy and immunotherapy (SAPPHIRE)
Published in Journal of clinical oncology (20-05-2020)“…Abstract only TPS9635 Background: Sitravatinib is an oral spectrum-selective tyrosine kinase inhibitor that targets the TAM (TYRO3/AXL/MERTK) and split…”
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13
A new algorithm for feature selection based on rough sets theory
Published in Revista Facultad de Ingeniería (31-03-2014)“…Rough Sets Theory has opened new trends for the development of data analysis techniques. In this theory, the notion of reduct is very significant, but…”
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Tappas: An adaptive enrichment phase 3 trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma (AAS)
Published in Journal of clinical oncology (20-05-2017)“…Abstract only TPS11081 Background: AAS is an aggressive soft tissue sarcoma (STS) of endothelial cell origin with an expected median overall survival of 8-12…”
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15
Biomarker modulation in patients treated with TRC105 in combination with anti-VEGF therapy
Published in Journal of clinical oncology (20-05-2017)“…Abstract only 11546 Background: TRC105, an endoglin-targeting monoclonal antibody with anti-angiogenic and anti-tumor activity, is being evaluated in multiple…”
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TAPPAS: An adaptive enrichment phase 3 trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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Detection of endoglin-expressing CTCs in patients enrolled in an adaptive enrichment phase 3 trial of TRC105 and pazopanib versus pazopanib alone in patients with advanced angiosarcoma (TAPPAS)
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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18
A phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) in combination with pazopanib in patients with advanced soft tissue sarcoma (STS)
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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19
A phase 1B/ phase 2A study of TRC105 (Endoglin Antibody) in combination with pazopanib (P) in patients (pts) with advanced soft tissue sarcoma (STS)
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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Biomarker modulation in patients (pts) receiving TRC105 (T) and bevacizumab (B) in a phase Ib clinical trial
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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