Search Results - "Alvarez, Carlos E."

One-particle engine with a porous piston by Álvarez, Carlos E., Camargo, Manuel, Téllez, Gabriel

“…We propose a variation of the classical Szilard engine that uses a porous piston. Such an engine requires neither information about the position of the…”
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On the origins of arrestin and rhodopsin by Alvarez, Carlos E

“…G protein coupled receptors (GPCRs) are the most numerous proteins in mammalian genomes, and the most common targets of clinical drugs. However, their…”
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Genetic testing of dogs predicts problem behaviors in clinical and nonclinical samples by Zapata, Isain, Lilly, M Leanne, Herron, Meghan E, Serpell, James A, Alvarez, Carlos E

“…Very little is known about the etiology of personality and psychiatric disorders. Because the core neurobiology of many such traits is evolutionarily…”
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Latent class analysis of behavior across dog breeds reveal underlying temperament profiles by Zapata, Isain, Eyre, Alexander W., Alvarez, Carlos E., Serpell, James A.

“…Latent class analysis (LCA) is a type of modeling analysis approach that has been used to identify unobserved groups or subgroups within multivariate…”
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Machine learning prediction and classification of behavioral selection in a canine olfactory detection program by Eyre, Alexander W., Zapata, Isain, Hare, Elizabeth, Serpell, James A., Otto, Cynthia M., Alvarez, Carlos E.

“…There is growing interest in canine behavioral research specifically for working dogs. Here we take advantage of a dataset of a Transportation Safety…”
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Genome scanning of behavioral selection in a canine olfactory detection breeding cohort by Eyre, Alexander W., Zapata, Isain, Hare, Elizabeth, Lee, Katharine M. N., Bellis, Claire, Essler, Jennifer L., Otto, Cynthia M., Serpell, James A., Alvarez, Carlos E.

“…Research on working dogs is growing rapidly due to increasing global demand. Here we report genome scanning of the risk of puppies being eliminated for…”
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Psychological Stress Is Associated with Increased Cancer Risk in Dogs by Zapata, Isain, Eyre, Alexander W, Alvarez, Carlos E

“…Although there is evidence that psychological stress may be associated with increased cancer risk, the effect of stress on cancer risk is difficult to study,…”
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Risk-modeling of dog osteosarcoma genome scans shows individuals with Mendelian-level polygenic risk are common by Zapata, Isain, Moraes, Luis E, Fiala, Elise M, Zaldivar-Lopez, Sara, Couto, C Guillermo, Rowell, Jennie L, Alvarez, Carlos E

“…Despite the tremendous therapeutic advances that have stemmed from somatic oncogenetics, survival of some cancers has not improved in 50 years. Osteosarcoma…”
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Analysis of Dystrophin Deletion Mutations Predicts Age of Cardiomyopathy Onset in Becker Muscular Dystrophy by Kaspar, Rita Wen, Allen, Hugh D, Ray, Will C, Alvarez, Carlos E, Kissel, John T, Pestronk, Alan, Weiss, Robert B, Flanigan, Kevin M, Mendell, Jerry R, Montanaro, Federica

“…Analysis of Dystrophin Deletion Mutations Predicts Age of Cardiomyopathy Onset in Becker Muscular Dystrophy Rita Wen Kaspar, PhD, RN ; Hugh D. Allen, MD ; Will…”
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Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC by Melhem, Alaa, Muhanna, Nidal, Bishara, Amal, Alvarez, Carlos E., Ilan, Yaron, Bishara, Taiser, Horani, Amjad, Nassar, Mithal, Friedman, Scott L., Safadi, Rifaat

“…We have investigated the role of natural killer (NK) cells in hepatic fibrogenesis. Mouse NK cells express both…”
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Mammalian α arrestins link activated seven transmembrane receptors to Nedd4 family e3 ubiquitin ligases and interact with β arrestins by Shea, Fortune F, Rowell, Jennie L, Li, Yechaowei, Chang, Tien-Hsien, Alvarez, Carlos E

“…The complement of fungal cell surface proteins is widely regulated by ubiquitination of membrane proteins, which results in their endocytosis and vacuolar…”
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Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats by Muñoz-Luque, Javier, Ros, Josefa, Fernández-Varo, Guillermo, Tugues, Sònia, Morales-Ruiz, Manuel, Alvarez, Carlos E, Friedman, Scott L, Arroyo, Vicente, Jiménez, Wladimiro

“…Two cannabinoid (CB) receptor subtypes, CB1 and CB2, have been cloned and characterized. Among other activities, receptor activation by cannabinoid ligands may…”
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Human Genetic Relevance and Potent Antitumor Activity of Heat Shock Protein 90 Inhibition in Canine Lung Adenocarcinoma Cell Lines by Clemente-Vicario, Francisco, Alvarez, Carlos E, Rowell, Jennie L, Roy, Satavisha, London, Cheryl A, Kisseberth, William C, Lorch, Gwendolen

“…It has been an open question how similar human and canine lung cancers are. This has major implications in availability of human treatments for dogs and in…”
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Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes by Safadi, Rifaat, Ohta, Masayuki, Alvarez, Carlos E., Fiel, M. Isabel, Bansal, Meena, Mehal, Wajahat Z., Friedman, Scott L.

“…Backgrounds & Aims: Immunomodulatory cytokines, including interleukin-10 (IL-10), may mediate hepatic fibrosis. Methods: We generated transgenic (TG) mice with…”
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Loss of Matrix Metalloproteinase-2 Amplifies Murine Toxin-Induced Liver Fibrosis by Upregulating Collagen I Expression by Radbill, Brian D, Gupta, Ritu, Ramirez, Maria Celeste M, DiFeo, Analisa, Martignetti, John A, Alvarez, Carlos E, Friedman, Scott L, Narla, Goutham, Vrabie, Raluca, Bowles, Robert, Saiman, Yedidya, Bansal, Meena B

“…Background and Aims Matrix metalloproteinase-2 (MMP-2), a type IV collagenase secreted by activated hepatic stellate cells (HSCs), is upregulated in chronic…”
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Genetic mapping of canine fear and aggression by Zapata, Isain, Serpell, James A, Alvarez, Carlos E

“…Fear/anxiety and anger/aggression greatly influence health, quality of life and social interactions. They are a huge burden to wellbeing, and personal and…”
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The ostomy experience in El Salvador: Shifting focus from stoma supply access to stoma quality by Schaps, Diego, Alvarez, Carlos E.

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Dog models of naturally occurring cancer by Rowell, Jennie L, McCarthy, Donna O, Alvarez, Carlos E

“…Studies using dogs provide an ideal solution to the gap in animal models for natural disease and translational medicine. This is evidenced by approximately 400…”
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Survey of vaccination practices in patients with diabetes: A report examining patient and provider perceptions and barriers by Alvarez, Carlos E., Clichici, Luciana, Patricia Guzmán-Libreros, Angela, Navarro-Francés, Mariola, Ena, Javier

“…In a cross-sectional study involving 279 patients with diabetes attending a primary care center the proportion of patients vaccinated for seasonal influenza,…”
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Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression by BANSAL, Meena B, KOVALOVICH, Kellen, TAUB, Rebecca A, GUPTA, Ritu, WEI LI, AGARWAL, Akansha, RADBILL, Brian, ALVAREZ, Carlos E, SAFADI, Rifaat, FIEL, M. Isabel, FRIEDMAN, Scott L

“…Interleukin-6 stimulates liver regeneration and promotes hepatoprotection following experimental liver injury, but underlying mechanisms have not been fully…”
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