Search Results - "Alty, Jane E"

Does serum neurofilament light help predict accelerated cognitive ageing in unimpaired older adults? by Collins, Jessica M., Bindoff, Aidan D., Roccati, Eddy, Alty, Jane E., Vickers, James C., King, Anna E.

“…Neurofilament light (NfL) is a blood biomarker of neurodegeneration. While serum NfL levels have been demonstrated to increase with normal ageing, the…”
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Accuracy of Smartphone Video for Contactless Measurement of Hand Tremor Frequency by Williams, Stefan, Fang, Hui, Relton, Samuel D., Wong, David C., Alam, Taimour, Alty, Jane E.

“…ABSTRACT Background Computer vision can measure movement from video without the time and access limitations of hospital accelerometry/electromyography or the…”
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Which figure copy test is more sensitive for cognitive impairment in Parkinson's disease: Wire cube or interlocking pentagons? by Alty, Jane E, Cosgrove, Jeremy, Jamieson, Stuart, Smith, Stephen L, Possin, Katherine L

“…Highlights • 63 PD patients completed MoCA and MMSE cognitive tests. • The figure copy tests were wire cube (MoCA) and interlocking pentagons (MMSE). • Cube…”
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The discerning eye of computer vision: Can it measure Parkinson's finger tap bradykinesia? by Williams, Stefan, Zhao, Zhibin, Hafeez, Awais, Wong, David C., Relton, Samuel D., Fang, Hui, Alty, Jane E.

“…The worldwide prevalence of Parkinson's disease is increasing. There is urgent need for new tools to objectively measure the condition. Existing methods to…”
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Deep learning of Parkinson's movement from video, without human-defined measures by Yang, Jiacheng, Williams, Stefan, Hogg, David C., Alty, Jane E., Relton, Samuel D.

“…The core clinical sign of Parkinson's disease (PD) is bradykinesia, for which a standard test is finger tapping: the clinician observes a person repetitively…”
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Parkinsonian Hand or Clinician’s Eye? Finger Tap Bradykinesia Interrater Reliability for 21 Movement Disorder Experts by Williams, Stefan, Wong, David, Alty, Jane E., Relton, Samuel D.

“…Background: Bradykinesia is considered the fundamental motor feature of Parkinson’s disease (PD). It is central to diagnosis, monitoring, and research…”
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Validation of computer vision technology for analyzing bradykinesia in outpatient clinic videos of people with Parkinson's disease by Heye, Kathrin, Li, Renjie, Bai, Quan, St George, Rebecca J., Rudd, Kaylee, Huang, Guan, Meinders, Marjan J., Bloem, Bastiaan R., Alty, Jane E.

“…Current diagnosis and monitoring of Parkinson's disease (PD) is based on subjective clinical assessments. Objective measures of motor functioning could support…”
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Parkinson’s disease diagnosis using convolutional neural networks and figure-copying tasks by Alissa, Mohamad, Lones, Michael A., Cosgrove, Jeremy, Alty, Jane E., Jamieson, Stuart, Smith, Stephen L., Vallejo, Marta

“…Parkinson’s disease (PD) is a progressive neurodegenerative disorder that causes abnormal movements and an array of other symptoms. An accurate PD diagnosis…”
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To the emergency room and back again: Circular healthcare pathways for acute functional neurological disorders by Williams, Stefan, Southall, Clea, Haley, Samantha, Ba Dhafari, Thamer, Kemp, Steven, Relton, Samuel D., Alty, Jane E., Johnson, Owen, Graham, Christopher D., Maguire, Melissa

“…Studies of Functional Neurological Disorders (FND) are usually outpatient-based. To inform service development, we aimed to describe patient pathways through…”
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Sex-Specific Protective Effects of Cognitive Reserve on Age-Related Cognitive Decline: A 5-Year Prospective Cohort Study by Alty, Jane E., Bindoff, Aidan D., Stuart, Kimberley E., Roccati, Eddy, Collins, Jessica M., King, Anna E., Summers, Mathew J., Vickers, James C.

“…Females have a higher age-adjusted incidence of Alzheimer disease than males but the reasons for this remain unclear. One proposed contributing factor is that,…”
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Significant cognitive decline in Parkinson's disease exacerbates the reliance on visual feedback during upper limb reaches by Cosgrove, Jeremy, Hinder, Mark R., St George, Rebecca J., Picardi, Chiara, Smith, Stephen L., Lones, Michael A., Jamieson, Stuart, Alty, Jane E.

“…While upper limb reaches are often made in a feed-forward manner, visual feedback during the movement can be used to guide the reaching hand towards a target…”
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Palliative care for Parkinson’s disease: A summary of the evidence and future directions by Richfield, Edward W, Jones, Edward JS, Alty, Jane E

“…Background: Parkinson’s disease is a common, life-limiting, neurodegenerative condition. Despite calls for improved access to palliative care for people with…”
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What type of tremor did the medieval 'Tremulous Hand of Worcester' have? by Thorpe, Deborah E, Alty, Jane E

“…The thirteenth-century medieval scribe, the ‘Tremulous Hand of Worcester’ is known for the tremor visible in his script. Thorpe & Alty combine historical…”
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Dystonia in a prolific medieval scribe by Thorpe, Deborah E, Melson, Nathan, Alty, Jane E

“…Studies of later historical figures and modern people with adult-onset dystonia have reported negative effects of the disease on working lives.3-5 By contrast,…”
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Seeing the unseen: Could Eulerian video magnification aid clinician detection of subclinical Parkinson’s tremor? by Williams, Stefan, Fang, Hui, Relton, Samuel D., Graham, Christopher D., Alty, Jane E.

“…•Eulerian video magnification reveals apparent subclinical tremor in Parkinson’s.•A contactless method uses standard smartphone video and a freely available…”
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Reply: Essential tremor in 'The tremulous hand of Worcester': additional comments by Thorpe, Deborah E, Alty, Jane E

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Evolving Classifiers to Recognize the Movement Characteristics of Parkinson's Disease Patients by Lones, Michael A., Smith, Stephen L., Alty, Jane E., Lacy, Stuart E., Possin, Katherine L., Jamieson, D. R. Stuart, Tyrrell, Andy M.

“…Parkinson's disease is a debilitating neurological condition that affects approximately 1 in 500 people and often leads to severe disability. To improve…”
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Inferring the long duration response to levodopa in Parkinson’s disease by Nagao, Kanae, Ding, Catherine, Ganga, Ganesvaran, Alty, Jane E., Clissold, Benjamin G., McColl, Craig D., Reardon, Katrina A., Schiff, Mark, Kempster, Peter A.

“…The long duration response to levodopa in Parkinson's disease outlasts drug elimination by days to weeks. Though a substantive part of anti-parkinsonian motor…”
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A practical guide to the differential diagnosis of tremor by Alty, Jane E, Kempster, Peter A

“…Tremor is, by definition, a rhythmic oscillation of a body part. It is the most prevalent movement disorder in clinical medicine, so doctors working in many…”
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A New Evolutionary Algorithm-Based Home Monitoring Device for Parkinson’s Dyskinesia by Lones, Michael A., Alty, Jane E., Cosgrove, Jeremy, Duggan-Carter, Philippa, Jamieson, Stuart, Naylor, Rebecca F., Turner, Andrew J., Smith, Stephen L.

“…Parkinson’s disease (PD) is a neurodegenerative movement disorder. Although there is no cure, symptomatic treatments are available and can significantly…”
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