Search Results - "Altomare, G"
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Italian guidelines on the systemic treatments of moderate‐to‐severe plaque psoriasis
Published in Journal of the European Academy of Dermatology and Venereology (01-05-2017)“…Psoriasis is a common disease, which has a considerable impact on the healthcare system. Therefore, appropriate use of therapeutic resources is very important…”
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Structure of a Vaccine-Induced, Germline-Encoded Human Antibody Defines a Neutralizing Epitope on the SARS-CoV-2 Spike N-Terminal Domain
Published in mBio (25-04-2022)“…Structural characterization of infection- and vaccination-elicited antibodies in complex with antigen provides insight into the evolutionary arms race between…”
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Nonsensory target-dependent organization of piriform cortex
Published in Proceedings of the National Academy of Sciences - PNAS (25-11-2014)“…The piriform cortex (PCX) is the largest component of the olfactory cortex and is hypothesized to be the locus of odor object formation. The distributed…”
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Anti-adalimumab antibodies in psoriasis: lack of clinical utility and laboratory evidence
Published in BMJ open (01-12-2016)“…ObjectiveAdalimumab has proven effective in psoriasis; however, secondary failure may result from the drug's immunogenicity. Prevalence data on the…”
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Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses
Published in Science immunology (24-12-2021)“…Initial exposure to a pathogen elicits an adaptive immune response to control and eradicate the threat. Interrogating the abundance and specificity of the…”
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Consensus on the management of patients with psoriatic arthritis in a dermatology setting
Published in Journal of the European Academy of Dermatology and Venereology (01-04-2018)“…Background Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis (PsO). Early diagnosis and prompt therapeutic intervention are…”
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The impact of biologic therapy in chronic plaque psoriasis from a societal perspective: an analysis based on Italian actual clinical practice
Published in Journal of the European Academy of Dermatology and Venereology (01-12-2015)“…Objective Psoriasis is one of the most common forms of chronic dermatitis, affecting 2–3% of the worldwide population. It has a serious effect on the way…”
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PSOCUBE, a multidimensional assessment of psoriasis patients as a both clinically/practically sustainable and evidence-based algorithm
Published in Journal of the European Academy of Dermatology and Venereology (01-07-2015)“…Background There is increasing awareness of the clinical relevance of psoriasis comorbidities and of the importance of timely and effective screening for such…”
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Differential expression of interleukin-2 by anti-CD3-stimulated peripheral blood mononuclear cells in patients with psoriatic arthritis and patients with cutaneous psoriasis
Published in Clinical and experimental dermatology (01-04-2014)“…Summary The differences in systemic T‐cell responses between patients with psoriatic arthritis (PsA) and patients with cutaneous psoriasis (Ps) are still…”
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Moderate and severe plaque psoriasis: cost-of-illness study in Italy
Published in Therapeutics and clinical risk management (01-04-2008)“…Psoriasis is a chronic inflammatory, immune-mediated skin disorder that affects 1.5-1.8 million people in Italy. The most common form of the disease is chronic…”
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Severe psoriasis treated with a new macrolide: everolimus
Published in British journal of dermatology (1951) (01-02-2007)“…Summary Psoriasis is an immune‐mediated disease with a chronic relapsing course, and the particularly severe forms that are refractory to traditional therapies…”
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Etanercept therapy in patients with psoriasis and concomitant HCV infection
Published in International journal of immunopathology and pharmacology (01-07-2010)“…Treatment of patients with psoriasis and/or psoriatic arthritis and concomitant hepatitis C infection remains difficult. Except for cyclosporine, other drugs…”
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Psoriasis relapse evaluation with week-end cyclosporine A treatment: results of a randomized, double-blind, multicenter study
Published in International journal of immunopathology and pharmacology (01-10-2010)“…Cyclosporine A (CsA) effectively controls psoriasis, however, its long-term continuous use is not recommended. This study aims to evaluate the efficacy and…”
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Psoriatic disease: concepts and implications
Published in Journal of the European Academy of Dermatology and Venereology (01-06-2010)Get full text
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P157 Inhibition of CCR7/CCL19 axis in psoriatic plaques is an early critical event for the clinical response to anti-TNF Therapy in psoriasis patients
Published in Cytokine (Philadelphia, Pa.) (01-09-2012)“…Psoriasis is a chronic inflammatory skin disease affecting approximately 2% of the population. Important clinical benefits in the treatment of psoriasis have…”
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A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants
Published in Immunity (Cambridge, Mass.) (14-09-2021)“…The emergence of SARS-CoV-2 antigenic variants with increased transmissibility is a public health threat. Some variants show substantial resistance to…”
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The protein kinase C inhibitor AEB071 (sotrastaurin) modulates migration and superoxide anion production by human neutrophils in vitro
Published in International journal of immunopathology and pharmacology (01-07-2012)“…We examined the effect of the protein kinase C-selective inhibitor AEB071 (sotrastaurin) on neutrophil functions in vitro. Pre-incubation with AEB071 at…”
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An Italian shared dermatological and rheumatological proposal for the use of biological agents in psoriatic disease
Published in Journal of the European Academy of Dermatology and Venereology (01-05-2010)“…Background As psoriatic disease (PD) is a condition characterized by the combination of inflammatory skin (psoriasis) and osteo‐articular manifestations…”
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Clinical outcome evaluation following cyclosporine a treatment in moderate to severe psoriasis: a retrospective study
Published in International journal of immunopathology and pharmacology (01-01-2010)“…This retrospective study was conducted on 193 patients treated in three Italian Psoriasis Units with the aim of evaluating the evolution of psoriasis severity…”
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