Search Results - "Altieri, Andrea"

Carcinogenicity of shift-work, painting, and fire-fighting by Straif, Kurt, Baan, Robert, Grosse, Yann, Secretan, Béatrice, Ghissassi, Fatiha El, Bouvard, Véronique, Altieri, Andrea, Benbrahim-Tallaa, Lamia, Cogliano, Vincent

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Targeting Virus-Induced Reprogrammed Cell Metabolism via Glycolytic Inhibitors: An Effective Therapeutic Approach Against SARS-CoV-2 by Sharma, Dolly, Singh, Mamta, Gupta, Rajat, Garg, Manoj, Altieri, Andrea, Kurkin, Alexander, Kumar, Vinit, Rani, Reshma

“…Reprogrammed cell metabolism has been observed in a wide range of virally infected cells. Viruses do not have their metabolism; they rely on the cellular…”
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Human acute exposure assessment to tropane alkaloids by Arcella, Davide, Altieri, Andrea

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Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists by Curreli, Francesca, Kwon, Young D, Nicolau, Isabella, Burgos, Giancarla, Altieri, Andrea, Kurkin, Alexander V, Verardi, Raffaello, Kwong, Peter D, Debnath, Asim K

“…As part of our effort to discover drugs that target HIV-1 entry, we report the antiviral activity and crystal structures of two novel inhibitors in a complex…”
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Risks for animal health related to the presence of zearalenone and its modified forms in feed by Knutsen, Helle‐Katrine, Alexander, Jan, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dinovi, Michael, Edler, Lutz, Grasl‐Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Nebbia, Carlo Stefano, Petersen, Annette, Rose, Martin, Roudot, Alain‐Claude, Schwerdtle, Tanja, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather, Dall'Asta, Chiara, Dänicke, Sven, Eriksen, Gunnar‐Sundstøl, Altieri, Andrea, Roldán‐Torres, Ruth, Oswald, Isabelle P

“…Zearalenone (ZEN), a mycotoxin primarily produced by Fusarium fungi, occurs predominantly in cereal grains. The European Commission asked EFSA for a scientific…”
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Comparative Pharmacokinetics of a Dual Inhibitor of HIV-1, NBD-14189, in Rats and Dogs with a Proof-of-Concept Evaluation of Antiviral Potency in SCID-hu Mouse Model by Stoddart, Cheryl A, Curreli, Francesca, Horrigan, Stephen, Altieri, Andrea, Kurkin, Alexander V, Debnath, Asim K

“…We earlier reported substantial progress in designing gp120 antagonists. Notably, we discovered that NBD-14189 is not only the most active gp120 antagonist but…”
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In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening by Iraci, Nunzio, Ostacolo, Carmine, Medina-Peris, Alicia, Ciaglia, Tania, Novoselov, Anton M, Altieri, Andrea, Cabañero, David, Fernandez-Carvajal, Asia, Campiglia, Pietro, Gomez-Monterrey, Isabel, Bertamino, Alessia, Kurkin, Alexander V

“…Transient receptor potential melastatin type 8 (TRPM8) is a target for the treatment of different physio-pathological processes. While TRPM8 antagonists are…”
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Generation, optimization and characterization of novel anti-prion compounds by Altieri, Andrea, Spiridonov, Evgeny A., Sivtzev, Semen I., Ishibashi, Daisuke, Biggi, Silvia, Nishida, Noriyuki, Biasini, Emiliano, Kurkin, Alexander V.

“…[Display omitted] Prions are misfolded proteins involved in neurodegenerative diseases of high interest in veterinary and public health. In this work, we…”
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Design, synthesis and evaluation of small molecule CD4-mimics as entry inhibitors possessing broad spectrum anti-HIV-1 activity by Curreli, Francesca, Belov, Dmitry S, Ramesh, Ranjith R, Patel, Naisargi, Altieri, Andrea, Kurkin, Alexander V, Debnath, Asim K

“…Since our first discovery of a CD4-mimic, NBD-556, which targets the Phe43 cavity of HIV-1 gp120, we and other groups made considerable progress in designing…”
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Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors by Franco, Jorge, Piacente, Francesco, Walter, Melanie, Fratta, Simone, Ghanem, Moustafa, Benzi, Andrea, Caffa, Irene, Kurkin, Alexander V., Altieri, Andrea, Herr, Patrick, Martínez-Bailén, Macarena, Robina, Inmaculada, Bruzzone, Santina, Nencioni, Alessio, Del Rio, Alberto

“…NAPRT, the rate-limiting enzyme of the Preiss–Handler NAD biosynthetic pathway, has emerged as a key biomarker for the clinical success of NAMPT inhibitors in…”
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Synthesis of Substituted Pyrrole Derivatives Based on 8-Azaspiro[5.6]dodec-10-ene Scaffold by Iusupov, Ildar R, Tafeenko, Victor A, Altieri, Andrea, Kurkin, Alexander V

“…This work describes the synthesis of spirocyclic compounds based on 8-azaspiro[5.6]dodec-10-ene. Diastereomerically pure pyrrole derivatives were prepared from…”
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Risks for animal health related to the presence of fumonisins, their modified forms and hidden forms in feed by Knutsen, Helle‐Katrine, Alexander, Jan, Barregård, Lars, Bignami, Margherita, Brüschweiler, Beat, Ceccatelli, Sandra, Cottrill, Bruce, Dinovi, Michael, Edler, Lutz, Grasl‐Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Nebbia, Carlo Stefano, Petersen, Annette, Rose, Martin, Roudot, Alain‐Claude, Schwerdtle, Tanja, Vleminckx, Christiane, Vollmer, Günter, Wallace, Heather, Dall'Asta, Chiara, Eriksen, Gunnar‐Sundstøl, Taranu, Ionelia, Altieri, Andrea, Roldán‐Torres, Ruth, Oswald, Isabelle P

“…Fumonisins, mycotoxins primarily produced by Fusarium verticillioides and Fusarium proliferatum, occur predominantly in cereal grains, especially in maize. The…”
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Re‐evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives by Mortensen, Alicja, Aguilar, Fernando, Crebelli, Riccardo, Di Domenico, Alessandro, Dusemund, Birgit, Frutos, Maria Jose, Galtier, Pierre, Gott, David, Gundert‐Remy, Ursula, Leblanc, Jean‐Charles, Lindtner, Oliver, Moldeus, Peter, Mosesso, Pasquale, Parent‐Massin, Dominique, Oskarsson, Agneta, Stankovic, Ivan, Waalkens‐Berendsen, Ine, Woutersen, Rudolf Antonius, Wright, Matthew, Younes, Maged, Boon, Polly, Chrysafidis, Dimitrios, Gürtler, Rainer, Tobback, Paul, Altieri, Andrea, Rincon, Ana Maria, Lambré, Claude

“…The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of glutamic acid–glutamates…”
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Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid by Curreli, Francesca, Zhang, Hongtao, Zhang, Xihui, Pyatkin, Ilya, Victor, Zagorodnikov, Altieri, Andrea, Debnath, Asim K.

“…The hydrophobic cavity of the C-terminal domain (CTD) of HIV-1 capsid has been recently validated as potential target for antiviral drugs by peptide-based…”
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(1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol Dihydrochloride by Iusupov, Ildar R., Lyssenko, Konstantin A., Altieri, Andrea, Kurkin, Alexander V.

“…The title compound (1RS,2RS,6RS)-2-(6-Amino-9H-purin-9-yl)-8-azaspiro[5.6]dodec-10-en-1-ol dihydrochloride was synthesized for the first time in two steps, the…”
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Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays by Curreli, Francesca, Ahmed, Shahad, Victor, Sofia M B, Drelich, Aleksandra, Panda, Siva S, Altieri, Andrea, Kurkin, Alexander V, Tseng, Chien-Te K, Hillyer, Christopher D, Debnath, Asim K

“…We report the discovery of several highly potent small molecules with low-nM potency against severe acute respiratory syndrome coronavirus (SARS-CoV; lowest…”
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Evaluation of the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels by Schrenk, Dieter, Bignami, Margherita, Bodin, Laurent, Chipman, James Kevin, del Mazo, Jesús, Grasl‐Kraupp, Bettina, Hogstrand, Christer, Hoogenboom, Laurentius (Ron), Leblanc, Jean‐Charles, Nebbia, Carlo Stefano, Nielsen, Elsa, Ntzani, Evangelia, Petersen, Annette, Sand, Salomon, Vleminckx, Christiane, Wallace, Heather, Benford, Diane, Brimer, Leon, Mancini, Francesca Romana, Metzler, Manfred, Viviani, Barbara, Altieri, Andrea, Arcella, Davide, Steinkellner, Hans, Schwerdtle, Tanja

“…In 2016, the EFSA Panel on Contaminants in the Food Chain (CONTAM) published a scientific opinion on the acute health risks related to the presence of…”
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Phosphorus-Based Functional Groups as Hydrogen Bonding Templates for Rotaxane Formation by Ahmed, Rehan, Altieri, Andrea, D’Souza, Daniel M, Leigh, David A, Mullen, Kathleen M, Papmeyer, Marcus, Slawin, Alexandra M. Z, Wong, Jenny K. Y, Woollins, J. Derek

“…We report on the use of the hydrogen bond acceptor properties of some phosphorus-containing functional groups for the assembly of a series of [2]rotaxanes…”
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Het(aryl)isatin to het(aryl)aminoindoline scaffold hopping: A route to selective inhibitors of matrix metalloproteinases by Ivanov, Vladimir N., Agamennone, Mariangela, Iusupov, Ildar R., Laghezza, Antonio, Novoselov, Anton M., Manasova, Ekaterina V., Altieri, Andrea, Tortorella, Paolo, Shtil, Alexander A., Kurkin, Alexander V.

“…[Display omitted] Matrix metalloproteinases (MMPs) are a large family of zinc-dependent endoproteases known to exert multiple regulatory roles in tumor…”
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Influence of education level on breast cancer risk and survival in Sweden between 1990 and 2004 by Hussain, Shehnaz K., Altieri, Andrea, Sundquist, Jan, Hemminki, Kari

“…On account of limited recent data regarding the role of education in breast cancer risk and prognosis, we conducted this study to assess the association…”
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