Search Results - "Althoff, Till F"
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Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation
Published in The Journal of experimental medicine (01-10-2018)“…The vascular endothelium is constantly exposed to mechanical forces, including fluid shear stress exerted by the flowing blood. Endothelial cells can sense…”
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2
Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP₃ receptors
Published in Proceedings of the National Academy of Sciences - PNAS (05-06-2012)“…Castor oil is one of the oldest drugs. When given orally, it has a laxative effect and induces labor in pregnant females. The effects of castor oil are…”
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3
Novel concepts in atrial fibrillation ablation—breaking the trade‐off between efficacy and safety
Published in Journal of arrhythmia (01-08-2021)“…Despite substantial technological and procedural advances that have improved the efficacy and safety of AF ablation in recent years, the long‐term durability…”
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4
Non-invasive assessment of pulmonary vein isolation durability using late gadolinium enhancement magnetic resonance imaging
Published in Europace (London, England) (16-02-2023)“…Electrical reconnection of pulmonary veins (PVs) is considered an important determinant of recurrent atrial fibrillation (AF) after pulmonary vein isolation…”
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5
Ablation Lesion Assessment with MRI
Published in Arrhythmia & electrophysiology review (01-04-2022)“…Late gadolinium enhancement (LGE) MRI is capable of detecting not only native cardiac fibrosis, but also ablation-induced scarring. Thus, it offers the unique…”
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6
Progressive and Simultaneous Right and Left Atrial Remodeling Uncovered by a Comprehensive Magnetic Resonance Assessment in Atrial Fibrillation
Published in Journal of the American Heart Association (18-10-2022)“…Background Left atrial structural remodeling contributes to the arrhythmogenic substrate of atrial fibrillation (AF), but the role of the right atrium (RA)…”
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7
Gq-Mediated Arrhythmogenic Signaling Promotes Atrial Fibrillation
Published in Biomedicines (11-02-2023)“…Background: Atrial fibrillation (AF) is promoted by various stimuli like angiotensin II, endothelin-1, epinephrine/norepinephrine, vagal activation, or…”
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8
Putting novel ablation technologies to the test
Published in Europace (London, England) (15-04-2023)“…Graphical Abstract Graphical Abstract…”
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9
Procontractile G protein-mediated signaling pathways antagonistically regulate smooth muscle differentiation in vascular remodeling
Published in The Journal of experimental medicine (19-11-2012)“…Vascular smooth muscle (Sm) cells (VSMCs) are highly plastic. Their differentiation state can be regulated by serum response factor (SRF), which activates…”
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10
Does the spatial distribution of atrial arrhythmogenic substrate matter? Insights from the DECAAF II trial
Published in Europace (London, England) (15-09-2023)“…Graphical Abstract Graphical abstract…”
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11
Catheter ablation of supraventricular tachycardias-a success story
Published in Europace (London, England) (08-02-2023)Get full text
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12
How to best assess ablation lesion formation with late gadolinium enhancement MRI
Published in Journal of cardiovascular electrophysiology (01-11-2020)Get full text
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13
Randomized study defining the optimum target interlesion distance in ablation index-guided atrial fibrillation ablation: Authors’ reply
Published in Europace (London, England) (21-05-2021)Get full text
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14
G-protein-mediated signaling in vascular smooth muscle cells — implications for vascular disease
Published in Journal of Molecular Medicine (01-09-2015)“…Differentiated vascular smooth muscle cells (VSMCs) are critical determinants of vascular tone and blood pressure. However, during vascular remodeling…”
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15
Long-term follow-up of a fenestrated Amplatzer atrial septal occluder in pulmonary arterial hypertension
Published in Chest (01-01-2008)“…Pulmonary arterial hypertension (PAH) is a progressive disease, with right-heart failure being the main cause of death. In patients refractory to conventional…”
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16
Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling
Published in Cardiovascular research (01-01-2016)“…Arterial hypertension is a major risk factor for cardiovascular diseases. The kidney and its natriuretic function are in the centre of the prevailing models to…”
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17
Randomized study defining the optimum target interlesion distance in ablation index-guided atrial fibrillation ablation
Published in Europace (London, England) (01-10-2020)“…While the CLOSE protocol proposes a maximally tolerable interlesion distance (ILD) of 6 mm for ablation index ablation index-guided atrial fibrillation (AF)…”
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18
Accuracy of left atrial fibrosis detection with cardiac magnetic resonance: correlation of late gadolinium enhancement with endocardial voltage and conduction velocity
Published in Europace (London, England) (08-03-2021)“…Abstract Aims Myocardial fibrosis is a hallmark of atrial fibrillation (AF) and its characterization could be used to guide ablation procedures. Late…”
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19
Management of Ventricular Arrhythmias in Heart Failure
Published in Current heart failure reports (01-08-2023)“…Purpose of Review Despite substantial progress in medical and device-based heart failure (HF) therapy, ventricular arrhythmias (VA) and sudden cardiac death…”
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Prediction of stroke risk based on left atrial appendage morphology: from pareidolia to artificial intelligence
Published in The International Journal of Cardiovascular Imaging (01-08-2021)Get full text
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