Search Results - "Althobaiti, Yusuf S"
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1
Oral self-administration of pregabalin in a mouse model and the resulting drug addiction features
Published in Saudi pharmaceutical journal (01-02-2024)“…Prescription drug abuse is an issue that is rapidly growing globally. Pregabalin, an anticonvulsant, analgesic, and anxiolytic medication, is effective in the…”
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2
Investigating the potential of mirtazapine to induce drug-seeking behavior in free-choice drinking mouse model
Published in Saudi pharmaceutical journal (01-12-2022)“…Addiction to various drugs and chemicals is a significant public health concern worldwide. Addiction to prescription medications has increased due to the…”
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3
Quetiapine-Induced Place Preference in Mice: Possible Dopaminergic Pathway
Published in Pharmaceuticals (Basel, Switzerland) (14-02-2021)“…Quetiapine, an atypical antipsychotic, is effective in the management of schizophrenia, depression, and anxiety. Although quetiapine overdosage and misuse have…”
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4
Progress in Clinical Trials of Photodynamic Therapy for Solid Tumors and the Role of Nanomedicine
Published in Cancers (29-09-2020)“…Current research to find effective anticancer treatments is being performed on photodynamic therapy (PDT) with increasing attention. PDT is a very promising…”
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5
A Machine Learning-Based Water Potability Prediction Model by Using Synthetic Minority Oversampling Technique and Explainable AI
Published in Computational intelligence and neuroscience (20-09-2022)“…During the last few decades, the quality of water has deteriorated significantly due to pollution and many other issues. As a consequence of this, there is a…”
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6
Spectroscopic and Molecular Docking Studies of Cu(II), Ni(II), Co(II), and Mn(II) Complexes with Anticonvulsant Therapeutic Agent Gabapentin
Published in Molecules (Basel, Switzerland) (05-07-2022)“…New Cu(II), Ni(II), Co(II), and Mn(II) complexes of the gabapentin (Gpn) bidentate drug ligand were synthesized and studied using elemental analyses, melting…”
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Spectrofluorometric quantitative analysis of aripiprazole based on quenching of natural derived carbon quantum dots in spiked human plasma
Published in Scientific reports (29-11-2023)“…Autism spectrum disorder is a significant concern worldwide, particularly in Middle Eastern countries. Aripiprazole, a psychiatric medicine that works as a…”
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8
Nanomaterials for Antiangiogenic Therapies for Cancer: A Promising Tool for Personalized Medicine
Published in International journal of molecular sciences (05-02-2021)“…Angiogenesis is one of the hallmarks of cancer. Several studies have shown that vascular endothelium growth factor (VEGF) plays a leading role in angiogenesis…”
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Downregulation of hepatic fat accumulation, inflammation and fibrosis by nerolidol in purpose built western-diet-induced multiple-hit pathogenesis of NASH animal model
Published in Biomedicine & pharmacotherapy (01-06-2022)“…Western diet style (fast food), which includes fatty frozen junk food, lard, processed meats, whole-fat dairy foods, cream, mayonnaise, butter, snacks, and…”
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10
Green synthesis of TiO2 bionanocomposite using waste leaves of water hyacinth: Application in antibacterial activity of toilet bacteria Serratia marcescens
Published in Materials letters (01-06-2022)“…[Display omitted] •Synthesis of TiO2 bionanocomposite from water hyacinth (WH) leaves extract.•Antibacterial activity of TiO2 bionanocomposite against S…”
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11
Cassia artemisiodes attenuates nociceptive and diabetes-induced neuropathic pain modalities apropos antioxidant and anti-inflammatory mechanisms
Published in Biomedicine & pharmacotherapy (01-05-2022)“…Cassia plants have a considerable position in conventional systems of medicine. The possible anti-nociceptive, anti-inflammatory, and anti-neuropathic…”
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12
Investigation into the Antihypertensive Effects of Diosmetin and Its Underlying Vascular Mechanisms Using Rat Model
Published in Pharmaceuticals (Basel, Switzerland) (30-07-2022)“…Diosmetin is a flavonoid that is found in many important medicinal plants that have antihypertensive therapeutic potential. Diosmetin has been shown to have…”
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13
The Psychological Impact of COVID-19 on Healthcare Workers in Saudi Arabia: A Year Later Into the Pandemic
Published in Frontiers in psychiatry (17-12-2021)“…The COVID-19 pandemic poses unprecedented challenges to healthcare workers worldwide. This study sought to estimate the prevalence of depression, anxiety, and…”
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14
Assessment of Agroeconomic Indicators of Sesamum indicum L. as Influenced by Application of Boron at Different Levels and Plant Growth Stages
Published in Molecules (Basel, Switzerland) (05-11-2021)“…To achieve the nutritional target of human food, boron (B) has been described as an essential mineral in determining seed and theoretical oil yield of L. The…”
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15
Application of Three Ecological Assessment Tools in Examining Chromatographic Methods for the Green Analysis of a Mixture of Dopamine, Serotonin, Glutamate and GABA: A Comparative Study
Published in Molecules (Basel, Switzerland) (07-09-2021)“…The assessment of greenness of analytical protocols is of great importance now to preserve the environment. Some studies have analyzed either only the…”
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16
Protective Effect of Vitamin D against Hepatic Molecular Apoptosis Caused by a High-Fat Diet in Rats
Published in Current issues in molecular biology (05-01-2023)“…The protective effects of vitamin D (VitD) in different diseases were studied. The liver is of great interest, especially with the presence of VitD receptors…”
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Ex vivo, in vitro, and in silico approaches to unveil the mechanisms underlying vasorelaxation effect of Mentha Longifolia (L.) in porcine coronary artery
Published in Biomedicine & pharmacotherapy (01-09-2022)“…Mentha (M.) longifolia (L.) is traditionally used for various ailments. The current study was intended to explore the underlying vasorelaxation mechanisms of…”
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18
Perception of Threat and Psychological Impact of COVID-19 among Expatriates in Makkah Region, Saudi Arabia
Published in International journal of environmental research and public health (21-06-2021)“…In the first few months of the pandemic, Makkah region reported the highest number of COVID-19 cases among all regions in Saudi Arabia. More than 80% of these…”
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Quercetin Alleviated Inflammasome-Mediated Pyroptosis and Modulated the mTOR/P70S6/P6/eIF4E/4EBP1 Pathway in Ischemic Stroke
Published in Pharmaceuticals (Basel, Switzerland) (01-08-2023)“…Stroke ranks as the world’s second most prevalent cause of mortality, and it represents a major public health concern with profound economic and social…”
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20
Effects of repeated high-dose methamphetamine and ceftriaxone post-treatments on tissue content of dopamine and serotonin as well as glutamate and glutamine
Published in Neuroscience letters (10-11-2016)“…•Methamphetamine caused depletion of dopamine and 5-HT in NAc and PFC.•Dopamine tissue content was restored with ceftriaxone post-treatment in…”
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