Search Results - "Altharawi, Ali"

Targeting Toxoplasma gondii ME49 TgAPN2: A Bioinformatics Approach for Antiparasitic Drug Discovery by Altharawi, Ali

“…As fewer therapeutic options are available for treating toxoplasmosis, newer antiparasitic drugs that can block TgAPN2 M1 aminopeptidase are of significant…”
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A Comparative Study between Screen-Printed and Solid-Contact Electrodes for the Stability-Indicating Determination of Bromazepam by Abdel-Gawad, Sherif A, Altharawi, Ali

“…Stability-indicating methods are awesome tools to ensure the safety and efficacy of active pharmaceutical ingredients (APIs). An accurate comparative study…”
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Synthesis, Anticancer Screening of Some Novel Trimethoxy Quinazolines and VEGFR2, EGFR Tyrosine Kinase Inhibitors Assay; Molecular Docking Studies by Altamimi, Abdulmalik S., El-Azab, Adel S., Abdelhamid, Sami G., Alamri, Mubarak A., Bayoumi, Ashraf H., Alqahtani, Safar M., Alabbas, Alhumaidi B., Altharawi, Ali I., Alossaimi, Manal A., Mohamed, Menshawy A.

“…A new series of 8-methoxy-2-trimethoxyphenyl-3-substituted quinazoline-4(3)-one compounds were designed, synthesized, and screened for antitumor activity…”
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A Novel Quantum Dots-Based Fluorescent Sensor for Determination of the Anticancer Dacomitinib: Application to Dosage Forms by Alossaimi, Manal A, Elmansi, Heba, Alajaji, Mai, Altharawi, Ali, Altamimi, Abdulmalik S A, Magdy, Galal

“…One of the most promising drugs recently approved for the treatment of various types of cancer is dacomitinib, which belongs to the tyrosine kinase inhibitor…”
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Structure-based virtual screening and molecular dynamics of phytochemicals derived from Saudi medicinal plants to identify potential COVID-19 therapeutics by Alamri, Mubarak A., Altharawi, Ali, Alabbas, Alhumaidi B., Alossaimi, Manal A., Alqahtani, Safar M.

“…Coronavirus disease 2019 (COVID-19) has affected almost every country in the world by causing a global pandemic with a high mortality rate. Lack of an…”
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Synchrotron Photothermal Infrared Nanospectroscopy of Drug-Induced Phospholipidosis in Macrophages by Chan, Ka Lung Andrew, Lekkas, Ioannis, Frogley, Mark D, Cinque, Gianfelice, Altharawi, Ali, Bello, Gianluca, Dailey, Lea Ann

“…Synchrotron resonance-enhanced infrared atomic force microscopy (RE-AFM-IR) is a near-field photothermal vibrational nanoprobe developed at Diamond Light…”
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Simultaneous Quantification of Some Fluoroquinolone Residues in Real Wastewater Effluents Using CZE by Abdel-Gawad, Sherif A, Altharawi, Ali

“…Since active pharmaceutical ingredients (APIs) are directly related to human health, monitoring and quantifying them in the environment is a crucial and…”
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From proteome to candidate vaccines: target discovery and molecular dynamics-guided multi-epitope vaccine engineering against kissing bug by Albaqami, Faisal F, Altharawi, Ali, Althurwi, Hassan N, Alharthy, Khalid M

“…is a protozoan parasite that causes the tropical ailment known as Chagas disease, which has its origins in South America. Globally, it has a major impact on…”
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Europinidin Inhibits Rotenone-Activated Parkinson's Disease in Rodents by Decreasing Lipid Peroxidation and Inflammatory Cytokines Pathways by Altharawi, Ali, Alharthy, Khalid M, Althurwi, Hassan N, Albaqami, Faisal F, Alzarea, Sami I, Al-Abbasi, Fahad A, Nadeem, Muhammad Shahid, Kazmi, Imran

“…Background: Europinidin is a derivative of delphinidin obtained from the plants Plumbago Europea and Ceratostigma plumbaginoides. This herb has wide medicinal…”
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An integrated computational approach towards novel drugs discovery against polyketide synthase 13 thioesterase domain of Mycobacterium tuberculosis by Altharawi, Ali, Alossaimi, Manal A., Alanazi, Mohammed M., Alqahatani, Safar M., Tahir ul Qamar, Muhammad

“…The acquired drug resistance by Mycobacterium tuberculosis (M. tuberculosis) to antibiotics urges the need for developing novel anti- M. tuberculosis drugs…”
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Novel 2-Sulfanylquinazolin-4(3 H )-one Derivatives as Multi-Kinase Inhibitors and Apoptosis Inducers: A Synthesis, Biological Evaluation, and Molecular Docking Study by Altharawi, Ali, Alanazi, Mohammed M, Alossaimi, Manal A, Alanazi, Ashwag S, Alqahtani, Safar M, Geesi, Mohammed H, Riadi, Yassine

“…The discovery of multi-targeted kinase inhibitors emerged as a potential strategy in the therapy of multi-genic diseases, such as cancer, that cannot be…”
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Microwave-assisted synthesis of novel Ti/BTB-MOFs as porous anticancer and antibacterial agents by Altharawi, Ali, Alqahtani, Safar M, Aldakhil, Taibah, Ahmad, Irfan

“…Nano compounds, especially metal-organic frameworks (MOFs), have significant properties. Among the most important properties of these compounds, which depend…”
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Novel and Potential Small Molecule Scaffolds as DYRK1A Inhibitors by Integrated Molecular Docking-Based Virtual Screening and Dynamics Simulation Study by Shahroz, Mir Mohammad, Sharma, Hemant Kumar, Altamimi, Abdulmalik S A, Alamri, Mubarak A, Ali, Abuzer, Ali, Amena, Alqahtani, Safar, Altharawi, Ali, Alabbas, Alhumaidi B, Alossaimi, Manal A, Riadi, Yassine, Firoz, Ahmad, Afzal, Obaid

“…The dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a novel, promising and emerging biological target for therapeutic intervention in…”
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System biology approach to identify the novel biomarkers in glioblastoma multiforme tumors by using computational analysis by Alqahtani, Safar M, Altharawi, Ali, Alabbas, Alhumaidi, Ahmad, Faisal, Ayaz, Hassan, Nawaz, Asia, Rahman, Sidra, Alossaimi, Manal A

“…The most common primary brain tumor in adults is glioblastoma multiforme (GBM), accounting for 45.2% of all cases. The characteristics of GBM, a highly…”
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Electrochemical DNA-nano biosensor for the detection of Goserelin as anticancer drug using modified pencil graphite electrode by Laylani, Layla Abd-Al-Sattar Sadiq, Al-Dolaimy, F, Altharawi, Ali, Sulaman, Ghasen M, Mustafa, Mohammed Ahmed, Alkhafaji, Adnan Taan, Alkhatami, Ali G

“…Goserelin is an effective anticancer drug, but naturally causes several side effects. Hence the determination of this drug in biological samples, plays a key…”
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Identifying the Responses from the Estrogen Receptor-Expressed MCF7 Cells Treated in Anticancer Drugs of Different Modes of Action Using Live-Cell FTIR Spectroscopy by Altharawi, Ali, Rahman, Khondaker Miraz, Chan, Ka Lung Andrew

“…Recently, we have shown that changes in Fourier transform infrared (FTIR) spectra of living MDA-MB-231 cells (a triple negative cell line) upon exposure to…”
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Butin prevent liver damage triggered by D-galactosamine via regulating lipid peroxidation and proinflammatory cytokines in rodents by Althurwi, Hassan N., Altharawi, Ali, Alharthy, Khalid M., Albaqami, Faisal F., Alzarea, Sami I., Al-Abbasi, Fahad A., Shahid Nadeem, Muhammad, Kazmi, Imran

“…Objectives: Liver damage is becoming a more severe problem around the world. Unfortunately, there is still a great need for clinically effective…”
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Ameliorative Effects of Isoeugenol and Eugenol against Impaired Nerve Function and Inflammatory and Oxidative Mediators in Diabetic Neuropathic Rats by Alharthy, Khalid M, Balaha, Mohamed F, Devi, Sushma, Altharawi, Ali, Yusufoglu, Hasan S, Aldossari, Rana M, Alam, Aftab, di Giacomo, Viviana

“…Diabetic polyneuropathy is characterized by structural abnormalities, oxidative stress, and neuroinflammation. The current study aimed to determine the…”
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Resveratrol-Loaded Chia Seed Oil-Based Nanogel as an Anti-Inflammatory in Adjuvant-Induced Arthritis by Afzal, Obaid, Altamimi, Abdulamalik S A, Alamri, Mubarak A, Altharawi, Ali, Alossaimi, Manal A, Akhtar, Md Sayeed, Tabassum, Fauzia, Almalki, Waleed H, Singh, Tanuja

“…Natural anti-inflammatory nutraceuticals may be useful in preventing rheumatoid arthritis from worsening. Resveratrol (RV) and chia seed oil, having…”
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Targeting IToxoplasma gondii/I ME49 TgAPN2: A Bioinformatics Approach for Antiparasitic Drug Discovery by Altharawi, Ali

“…As fewer therapeutic options are available for treating toxoplasmosis, newer antiparasitic drugs that can block TgAPN2 M1 aminopeptidase are of significant…”
Get full text