Search Results - "Althagafi, Marwan"

Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction by Dick, Sarah A., Macklin, Jillian A., Nejat, Sara, Momen, Abdul, Clemente-Casares, Xavier, Althagafi, Marwan G., Chen, Jinmiao, Kantores, Crystal, Hosseinzadeh, Siyavash, Aronoff, Laura, Wong, Anthony, Zaman, Rysa, Barbu, Iulia, Besla, Rickvinder, Lavine, Kory J., Razani, Babak, Ginhoux, Florent, Husain, Mansoor, Cybulsky, Myron I., Robbins, Clinton S., Epelman, Slava

“…Macrophages promote both injury and repair after myocardial infarction, but discriminating functions within mixed populations remains challenging. Here we used…”
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Plasma S1P Orchestrates the Reverse Transendothelial Migration of Aortic Intimal Myeloid Cells in Mice by Polenz, Chanele K, Scipione, Corey A, Hyduk, Sharon J, Althagafi, Marwan G, Ibrahim, Hisham M, Cybulsky, Myron I

“…Myeloid cells (MCs) reside in the aortic intima at regions predisposed to atherosclerosis. Systemic inflammation triggers reverse transendothelial migration…”
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Role of myeloid-derived chemokine CCL5/RANTES at an early stage of atherosclerosis by Jongstra-Bilen, Jenny, Tai, Kelly, Althagafi, Marwan G., Siu, Allan, Scipione, Corey A., Karim, Saraf, Polenz, Chanele K., Ikeda, Jiro, Hyduk, Sharon J., Cybulsky, Myron I.

“…One of the hallmarks of atherosclerosis is ongoing accumulation of macrophages in the artery intima beginning at disease onset. Monocyte recruitment…”
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Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche by Emoto, Takuo, Lu, Jessie, Sivasubramaniyam, Tharini, Maan, Hassaan, Khan, Aniqa B., Abow, Amina A., Schroer, Stephanie A., Hyduk, Sharon J., Althagafi, Marwan G., McKee, Trevor D., Fu, Fred, Shabro, Shiva, Ulndreaj, Antigona, Chiu, Felix, Paneda, Elvira, Pacheco, Shaun, Wang, Tao, Li, Angela, Jiang, Jean X., Libby, Peter, Husain, Mansoor, Wang, Bo, Rubin, Barry B., Cybulsky, Myron I., Robbins, Clinton S.

“…Macrophage colony stimulating factor-1 (CSF-1) plays a critical role in maintaining myeloid lineage cells. However, congenital global deficiency of CSF-1…”
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Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation by Ikeda, Jiro, Scipione, Corey A., Hyduk, Sharon J., Althagafi, Marwan G., Atif, Jawairia, Dick, Sarah A., Rajora, Maneesha, Jang, Erika, Emoto, Takuo, Murakami, Junichi, Ikeda, Noriko, Ibrahim, Hisham M., Polenz, Chanele K., Gao, Xiaotang, Tai, Kelly, Jongstra-Bilen, Jenny, Nakashima, Ryota, Epelman, Slava, Robbins, Clinton S., Zheng, Gang, Lee, Warren L., MacParland, Sonya A., Cybulsky, Myron I.

“…Bone marrow transplantation (BMT) is used frequently to study the role of hematopoietic cells in atherosclerosis, but aortic arch lesions are smaller in mice…”
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Publisher Correction: Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction by Dick, Sarah A., Macklin, Jillian A., Nejat, Sara, Momen, Abdul, Clemente-Casares, Xavier, Althagafi, Marwan G., Chen, Jinmiao, Kantores, Crystal, Hosseinzadeh, Siyavash, Aronoff, Laura, Wong, Anthony, Zaman, Rysa, Barbu, Iulia, Besla, Rickvinder, Lavine, Kory J., Razani, Babak, Ginhoux, Florent, Husain, Mansoor, Cybulsky, Myron I., Robbins, Clinton S., Epelman, Slava

“…In the version of this article initially published, the equal contribution of the third author was omitted. The footnote links for that author should be “Sara…”
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Abstract 499: A Novel En Face Ex Vivo Live Imaging Approach For The Visualization Of Intimal Myeloid Cell Dynamics by Polenz, Chanele K, Ibrahim, Hisham, Althagafi, Marwan, Scipione, Corey A, Hyduk, Sharon, Cybulsky, Myron I

“…Abstract only Populations of CD11c + intimal myeloid cells (MCs) are known to reside in regions of the vasculature predisposed to atherosclerosis, such as the…”
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Abstract 462: Transcriptomic Analysis Reveals That Intimal Monocytes Drive Inflammation In Early Atherogenesis by Scipione, Corey A, Hyduk, Sharon J, Polenz, Chanele K, Althagafi, Marwan G, Prattas, Stylianos Z, Ibrahim, Hisham M, MacParland, Sonya A, Cybulsky, Myron I

“…Abstract only Hypercholesterolemia (HC) is a key risk factor for atherosclerosis, a chronic inflammatory disease that causes myocardial infarction and stroke…”
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Abstract 412: Transcriptomic Analysis Reveals That Lipid Loading Of Distinct Intimal Myeloid Cell Subpopulations Precedes Inflammation In Early Atherogenesis by Scipione, Corey A, Hyduk, Sharon J, Polenz, Chanele K, Althagafi, Marwan G, Ibrahim, Hisham M, MacParland, Sonya A, Cybulsky, Myron I

“…Hypercholesterolemia (HC) is a key risk factor of atherosclerosis, a chronic inflammatory disease that causes myocardial infarction and stroke. Although all…”
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Abstract 2010: Atherosclerotic Plaque Macrophages Drive Abdominal Aortic Aneurysm Formation by Khan, Aniqa, Thayaparan, Danya, Emoto, Takuo, Besla, Rickvinder, Hamidzada, Homaira, Vohra, Shabana, Lindquist, Moritz, Botts, Steven R, El-Maklizi, Mahmoud, Schroer, Stephanie, Althagafi, Marwan, Zhang, Hangjun, Libby, Peter, Howe, Kathryn L, Heximer, Scott P, Rubin, Barry B, Cybulsky, Myron I, Roy, Joy, Epelman, Slava, Ken-ichi, Hirata, Stampfli, Martin, Robbins, Clint S

“…Abstract only Introduction: Cigarette smoking (CS) contributes to the most deaths in abdominal aortic aneurysms (AAA) and tobacco use associates with early…”
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CCL19-CCR7–dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima by Roufaiel, Mark, Gracey, Eric, Siu, Allan, Zhu, Su-Ning, Lau, Andrew, Ibrahim, Hisham, Althagafi, Marwan, Tai, Kelly, Hyduk, Sharon J, Cybulsky, Kateryna O, Ensan, Sherine, Li, Angela, Besla, Rickvinder, Becker, Henry M, Xiao, Haiyan, Luther, Sanjiv A, Inman, Robert D, Robbins, Clinton S, Jongstra-Bilen, Jenny, Cybulsky, Myron I

“…Cybulsky and colleagues show that myeloid cells in the arterial intima undergo reverse transendothelial migration into the arterial circulation that is…”
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CSF1 Maintains Myeloid Cell Homeostasis in the Aortic Intima by Althagafi, Marwan G

“…Myeloid cells reside in all normal tissues including normal arteries and their abundance is tightly regulated. In the normal mouse aortic intima, myeloid cell…”
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Radiation Impacts Early Atherosclerosis by Suppressing Intimal LDL Accumulation by Ikeda, Jiro, Scipione, Corey A., Hyduk, Sharon J., Althagafi, Marwan G., Atif, Jawairia, Dick, Sarah A., Rajora, Maneesha, Jang, Erika, Emoto, Takuo, Murakami, Junichi, Ikeda, Noriko, Ibrahim, Hisham M., Polenz, Chanele K., Gao, Xiaotang, Tai, Kelly, Jongstra-Bilen, Jenny, Nakashima, Ryota, Epelman, Slava, Robbins, Clinton S., Zheng, Gang, Lee, Warren L., MacParland, Sonya A., Cybulsky, Myron I.

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Erratum: CCL19-CCR7–dependent reverse transendothelial migration of myeloid cells clears Chlamydia muridarum from the arterial intima by Roufaiel, Mark, Gracey, Eric, Siu, Allan, Zhu, Su-Ning, Lau, Andrew, Ibrahim, Hisham, Althagafi, Marwan, Tai, Kelly, Hyduk, Sharon J, Cybulsky, Kateryna O, Ensan, Sherine, Li, Angela, Besla, Rickvinder, Becker, Henry M, Xiao, Haiyan, Luther, Sanjiv A, Inman, Robert D, Robbins, Clinton S, Jongstra-Bilen, Jenny, Cybulsky, Myron I

“…Nat. Immunol. 17, 1263–1272 (2016); published online 26 September 2016; corrected after print 20 March 2017 In the version of this article initially published,…”
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Abstract 16226: Lyve-1 Negative Bone Marrow-Derived Macrophages Drive Aortic Aneurysm/Dissection by Li, Angela, Besla, Rickvinder, Chen, Emily, Pacheco, Shaun, Emoto, Takuo, Althagafi, Marwan, Cybulsky, Myron I, Robbins, Clint S, Byrne, John S

“…IntroductionAortic aneurysms are characterized by macrophage mediated inflammation. Lyve-1 resident aortic macrophages independently self-renew, and are…”
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The Role of CX3CL1 and CSF1 in Maintaining Myeloid Cell Homeostasis in the Intima and Adventitia of the Aorta by Althagafi, Marwan G., Robbins, Clinton S., Cybulsky, Myron I.

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