Search Results - "Alter, Claudio Luca"
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Incorporation of phosphatidylserine improves efficiency of lipid based gene delivery systems
Published in European journal of pharmaceutics and biopharmaceutics (01-03-2022)“…Non-viral nucleic acid therapies rely on the use of lipid nanoparticles (LNPs). Bioinspired LNPs decorated with the viral envelope lipid phosphatidylserine…”
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Zebrafish Larvae as an in vivo Model for Antimicrobial Activity Tests against Intracellular Salmonella
Published in Frontiers in bioscience (Landmark. Print) (25-05-2023)“…Blood infections from multi-drug-resistant pose a major health burden. This is especially true because can survive and replicate intracellularly, and the…”
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Zebrafish ( Danio rerio ) larva as an in vivo vertebrate model to study renal function
Published in American journal of physiology. Renal physiology (01-03-2022)“…There is an increasing interest in using zebrafish ( ) larva as a vertebrate screening model to study drug disposition. As the pronephric kidney of zebrafish…”
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Comparison of ionizable lipids for lipid nanoparticle mediated DNA delivery
Published in European journal of pharmaceutical sciences (01-12-2024)“…•DNA delivery via lipid nanoparticle (LNP) formulations is underexplored.•Our study combines DNA expression plasmids with clinically used ionizable lipids.•In…”
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Nano Plasma Membrane Vesicle‐Lipid Nanoparticle Hybrids for Enhanced Gene Delivery and Expression
Published in Advanced healthcare materials (10-11-2024)“…Abstract Lipid nanoparticles (LNPs) have emerged as the leading nonviral nucleic acid (NA) delivery system, gaining widespread attention for their use in…”
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