Search Results - "Altendorfer, B."
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CD8+ T-cells infiltrate Alzheimer’s disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice
Published in Brain, behavior, and immunity (01-10-2020)“…•CD8+ T-cells infiltrate the brain in aging and human AD pathology.•CD8+ T-cells can successfully be ablated from blood and brain using an anti-CD8 antibody…”
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Reconditioning the Neurogenic Niche of Adult Non-human Primates by Antisense Oligonucleotide-Mediated Attenuation of TGFβ Signaling
Published in Neurotherapeutics (01-07-2021)“…Adult neurogenesis is a target for brain rejuvenation as well as regeneration in aging and disease. Numerous approaches showed efficacy to elevate neurogenesis…”
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Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study: EBioMedicine
Published in EBioMedicine (25-01-2021)“…BACKGROUND: Brain lipid metabolism appears critical for cognitive aging, but whether alterations in the lipidome relate to cognitive decline remains unclear at…”
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Métabolites dérivés du microbiote intestinal et déclin cognitif : une exploration de l’axe intestin-cerveau
Published in Nutrition clinique et métabolisme (01-02-2022)“…Le microbiote intestinal (MI) participe à la digestion et au métabolisme de nombreux nutriments en libérant des métabolites dans le tube digestif, dont…”
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