Search Results - "Altas, Bekir"

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18 by Lai, Ying, Choi, Ucheor B., Leitz, Jeremy, Rhee, Hong Jun, Lee, Choongku, Altas, Bekir, Zhao, Minglei, Pfuetzner, Richard A., Wang, Austin L., Brose, Nils, Rhee, JeongSeop, Brunger, Axel T.

“…Munc13 catalyzes the transit of syntaxin from a closed complex with Munc18 into the ternary SNARE complex. Here we report a new function of Munc13, independent…”
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Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release by Sigler, Albrecht, Oh, Won Chan, Imig, Cordelia, Altas, Bekir, Kawabe, Hiroshi, Cooper, Benjamin H., Kwon, Hyung-Bae, Rhee, Jeong-Seop, Brose, Nils

“…Dendritic spines are the major transmitter reception compartments of glutamatergic synapses in most principal neurons of the mammalian brain and play a key…”
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The murine ortholog of Kaufman oculocerebrofacial syndrome protein Ube3b regulates synapse number by ubiquitinating Ppp3cc by Ambrozkiewicz, Mateusz C., Borisova, Ekaterina, Schwark, Manuela, Ripamonti, Silvia, Schaub, Theres, Smorodchenko, Alina, Weber, A. Ioana, Rhee, Hong Jun, Altas, Bekir, Yilmaz, Rüstem, Mueller, Susanne, Piepkorn, Lars, Horan, Stephen T., Straussberg, Rachel, Zaqout, Sami, Jahn, Olaf, Dere, Ekrem, Rosário, Marta, Boehm-Sturm, Philipp, Borck, Guntram, Willig, Katrin I., Rhee, JeongSeop, Tarabykin, Victor, Kawabe, Hiroshi

“…Kaufman oculocerebrofacial syndrome (KOS) is a severe autosomal recessive disorder characterized by intellectual disability, developmental delays,…”
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Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses by Maus, Lydia, Lee, ChoongKu, Altas, Bekir, Sertel, Sinem M., Weyand, Kirsten, Rizzoli, Silvio O., Rhee, JeongSeop, Brose, Nils, Imig, Cordelia, Cooper, Benjamin H.

“…Although similar in molecular composition, synapses can exhibit strikingly distinct functional transmitter release and plasticity characteristics. To determine…”
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Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140 by Ambrozkiewicz, Mateusz C., Schwark, Manuela, Kishimoto-Suga, Mika, Borisova, Ekaterina, Hori, Kei, Salazar-Lázaro, Andrea, Rusanova, Alexandra, Altas, Bekir, Piepkorn, Lars, Bessa, Paraskevi, Schaub, Theres, Zhang, Xin, Rabe, Tamara, Ripamonti, Silvia, Rosário, Marta, Akiyama, Haruhiko, Jahn, Olaf, Kobayashi, Tatsuya, Hoshino, Mikio, Tarabykin, Victor, Kawabe, Hiroshi

“…The establishment of axon-dendrite polarity is fundamental for radial migration of neurons during cortex development of mammals. We demonstrate that the E3…”
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Neuronal mTOR Outposts: Implications for Translation, Signaling, and Plasticity by Altas, Bekir, Romanowski, Andrea J, Bunce, Garrett W, Poulopoulos, Alexandros

“…The kinase mTOR is a signaling hub for pathways that regulate cellular growth. In neurons, the subcellular localization of mTOR takes on increased…”
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1528-P: Investigate Functional Dynamics of Neuropeptides in Acute Brain Slices to Predict Anorexigenic Efficacy by Pekcec, Anton, Altas, Bekir, Bruschetta, Giuseppe, Buzzanca, Anna, Doerr, Jonas, Lam, Daniel, Lincoln, Kathleen A, Mack, Volker

“…Obesity represents the largest and rapidly escalating global health crisis in the world, predominantly attributed to a disequilibrium between caloric intake…”
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Biochemical Purification of Binding Partners of Synaptic Scaffold Proteins by Altas, Bekir, Jahn, Olaf, Kawabe, Hiroshi

“…The chemical synapse displays specialized intercellular adhesion between pre- and potsynaptic plasma membranes mediated by synaptic cell adhesion proteins. In…”
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Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory Versus Inhibitory Synapses by Altas, Bekir, Tuffy, Liam P., Patrizi, Annarita, Dimova, Kalina, Soykan, Tolga, Brandenburg, Cheryl, Romanowski, Andrea J., Whitten, Julia R., Robertson, Colin D., Khim, Saovleak N., Crutcher, Garrett W., Ambrozkiewicz, Mateusz C., Yagensky, Oleksandr, Krueger-Burg, Dilja, Hammer, Matthieu, Hsiao, He-Hsuan, Laskowski, Pawel R., Dyck, Lydia, Puche, Adam C., Sassoè-Pognetto, Marco, Chua, John J.E., Urlaub, Henning, Jahn, Olaf, Brose, Nils, Poulopoulos, Alexandros

“…Neuroligin-3 is a postsynaptic adhesion molecule involved in synapse development and function. It is implicated in rare, monogenic forms of autism, and its…”
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Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity by Altas, Bekir, Rhee, Hong-Jun, Ju, Anes, Solís, Hugo Cruces, Karaca, Samir, Winchenbach, Jan, Kaplan-Arabaci, Oykum, Schwark, Manuela, Ambrozkiewicz, Mateusz C, Lee, ChungKu, Spieth, Lena, Wieser, Georg L, Chaugule, Viduth K, Majoul, Irina, Hassan, Mohamed A, Goel, Rashi, Wojcik, Sonja M, Koganezawa, Noriko, Hanamura, Kenji, Rotin, Daniela, Pichler, Andrea, Mitkovski, Miso, de Hoz, Livia, Poulopoulos, Alexandros, Urlaub, Henning, Jahn, Olaf, Saher, Gesine, Brose, Nils, Rhee, JeongSeop, Kawabe, Hiroshi

“…Nedd4-2 is an E3 ubiquitin ligase in which missense mutation is related to familial epilepsy, indicating its critical role in regulating neuronal network…”
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Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury by Ott, Christoph, Martens, Henrik, Hassouna, Imam, Oliveira, Bárbara, Erck, Christian, Zafeiriou, Maria-Patapia, Peteri, Ulla-Kaisa, Hesse, Dörte, Gerhart, Simone, Altas, Bekir, Kolbow, Tekla, Stadler, Herbert, Kawabe, Hiroshi, Zimmermann, Wolfram-Hubertus, Nave, Klaus-Armin, Schulz-Schaeffer, Walter, Jahn, Olaf, Ehrenreich, Hannelore

“…Erythropoietin (EPO) exerts potent neuroprotective, neuroregenerative and procognitive functions. However, unequivocal demonstration of erythropoietin receptor…”
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Enhancing Precision and Efficiency of Cas9-Mediated Knockin Through Combinatorial Fusions of DNA Repair Proteins by Richardson, Ryan R, Steyert, Marilyn, Khim, Saovleak N, Crutcher, Garrett W, Brandenburg, Cheryl, Robertson, Colin D, Romanowski, Andrea J, Inen, Jeffrey, Altas, Bekir, Poulopoulos, Alexandros

“…Cas9 targets genomic loci with high specificity. For knockin with double-strand break repair, however, Cas9 often leads to unintended on-target knockout rather…”
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Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson's disease by Canal, Mercè, Martín-Flores, Núria, Pérez-Sisqués, Leticia, Romaní-Aumedes, Joan, Altas, Bekir, Man, Heng-Ye, Kawabe, Hiroshi, Alberch, Jordi, Malagelada, Cristina

“…Parkinson's disease (PD) is a disorder characterized by the degeneration of certain neuronal populations in the central and peripheral nervous system. One of…”
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BDNF enhances spontaneous and activity-dependent neurotransmitter release at excitatory terminals but not at inhibitory terminals in hippocampal neurons by Shinoda, Yo, Ahmed, Saheeb, Ramachandran, Binu, Bharat, Vinita, Brockelt, David, Altas, Bekir, Dean, Camin

“…Brain-derived neurotrophic factor (BDNF) is widely reported to enhance synaptic vesicle (SV) exocytosis and neurotransmitter release. But it is still unclear…”
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Erratum to: Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury by Ott, Christoph, Martens, Henrik, Hassouna, Imam, Oliveira, Barbara, Erck, Christian, Zafeiriou, Maria-Patapia, Peteri, Ulla-Kaisa, Hesse, Dörte, Gerhart, Simone, Altas, Bekir, Kolbow, Tekla, Stadler, Herbert, Kawabe, Hiroshi, Zimmermann, Wolfram-Hubertus, Nave, Klaus-Armin, Schulz-Schaeffer, Walter, Jahn, Olaf, Ehrenreich, Hannelore

“…Author information Affiliations* Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany Christoph Ott, Imam Hassouna, Barbara…”
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