Search Results - "Altankov, George"
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Three Dimensional Honeycomb Patterned Fibrinogen Based Nanofibers Induce Substantial Osteogenic Response of Mesenchymal Stem Cells
Published in Scientific reports (21-11-2017)“…Stem cells therapy offers a viable alternative for treatment of bone disorders to the conventional bone grafting. However clinical therapies are still hindered…”
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Mesenchymal Stem-Cell Remodeling of Adsorbed Type-I Collagen-The Effect of Collagen Oxidation
Published in International journal of molecular sciences (11-03-2022)“…This study describes the effect of collagen type I (Col I) oxidation on its physiological remodeling by adipose tissue-derived mesenchymal stem cells (ADMSCs),…”
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Fibronectin/thermo-responsive polymer scaffold as a dynamic ex vivo niche for mesenchymal stem cells
Published in Journal of materials science. Materials in medicine (01-12-2020)“…In this paper, we created a dynamic adhesive environment (DAE) for adipose tissue-derived mesenchymal stem cells (ADMSCs) cultured on smart thermo-responsive…”
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Altered Mesenchymal Stem Cells Mechanotransduction from Oxidized Collagen: Morphological and Biophysical Observations
Published in International journal of molecular sciences (01-02-2023)“…Extracellular matrix (ECM) provides various mechanical cues that are able to affect the self-renewal and differentiation of mesenchymal stem cells (MSC)…”
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Early Stages of Ex Vivo Collagen Glycation Disrupt the Cellular Interaction and Its Remodeling by Mesenchymal Stem Cells-Morphological and Biochemical Evidence
Published in International journal of molecular sciences (01-06-2024)“…Mesenchymal stem cells (MSCs), pivotal for tissue repair, utilize collagen to restore structural integrity in damaged tissue, preserving its organization…”
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Porous hydroxyapatite and gelatin/hydroxyapatite microspheres obtained by calcium phosphate cement emulsion
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-04-2011)“…Hydroxyapatite and hybrid gelatine/hydroxyapatite microspheres were obtained through a water in oil emulsion of a calcium phosphate cement (CPC). The setting…”
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Recombinant fibronectin fragment III8-10/polylactic acid hybrid nanofibers enhance the bioactivity of titanium surface
Published in Nanomedicine (London, England) (01-04-2018)“…To develop a nanofiber (NF)-based biomimetic coating on titanium (Ti) that mimics the complex spatiotemporal organization of the extracellular matrix (ECM)…”
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Vitronectin alters fibronectin organization at the cell–material interface
Published in Colloids and surfaces, B, Biointerfaces (01-11-2013)“…Vitronectin favors fibronectin adsorption and facilitates the cell-mediated fibronectin reorganization. •We identify the role of vitronectin in material-driven…”
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Dynamic cell culture on calcium phosphate microcarriers for bone tissue engineering applications
Published in Journal of tissue engineering (01-01-2014)“…Developing appropriate cell culturing techniques to populate scaffolds has become a great challenge in tissue engineering. This work describes the use of…”
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Surface modifications of silicon nitride for cellular biosensor applications
Published in Journal of materials science. Materials in medicine (01-04-2008)“…Thin films of silicon nitride (Si 3 N 4 ) can be used in several kinds of micro-sized biosensors as a material to monitor fine environmental changes related to…”
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Studies on cell-biomaterial interaction: role of tyrosine phosphorylation during fibroblast spreading on surfaces varying in wettability
Published in Biomaterials (01-06-1996)“…In a previous study we observed that protein tyrosine phosphorylation was significantly diminished in the focal adhesions of human fibroblasts attached on a…”
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Molecular composition of GAG-collagen I multilayers affects remodeling of terminal layers and osteogenic differentiation of adipose-derived stem cells
Published in Acta biomaterialia (01-09-2016)“…[Display omitted] The effect of molecular composition of multilayers, by pairing type I collagen (Col I) with either hyaluronic acid (HA) or chondroitin…”
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Angular-Substituted 1,4Thiazino3,4-aIsoquinolines: Biological Evaluation and In Silico Studies on DPP-IV Inhibition
Published in International journal of molecular sciences (01-11-2024)“…Recent studies have discovered that aryl-substituted pyrido[2,1-a]isoquinolines have the potential to be highly active DPP IV inhibitors. In previous studies,…”
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Angular-Substituted [1,4]Thiazino[3,4-a]Isoquinolines: Biological Evaluation and In Silico Studies on DPP-IV Inhibition
Published in International journal of molecular sciences (01-11-2024)“…Recent studies have discovered that aryl-substituted pyrido[2,1-a]isoquinolines have the potential to be highly active DPP IV inhibitors. In previous studies,…”
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Establishing multiple osteogenic differentiation pathways of mesenchymal stem cells through different scaffold configurations
Published in Journal of tissue engineering and regenerative medicine (01-10-2020)“…Mimicking the complex organization of the extracellular matrix (ECM), especially its structure and dimensionality, is necessary to produce living tissues from…”
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PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation
Published in Toxicology and applied pharmacology (01-10-2018)“…PIKfyve phosphoinositide kinase produces PtdIns(3,5)P2 and PtdIns5P and governs a myriad of cellular processes including cytoskeleton rearrangements and cell…”
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The strength of the protein-material interaction determines cell fate
Published in Acta biomaterialia (01-09-2018)“…ECM proteins adsorbed on the material surface are reorganised by cells after the initial cell-protein interaction. However, cells respond with proteolytic…”
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Type IV collagen conforms to the organization of polylaminin adsorbed on planar substrata
Published in Acta biomaterialia (15-07-2020)“…Tissue engineering demands the development of scaffolds that mimic natural extracellular matrices (ECM). Despite the success in obtaining synthetic…”
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Morphological and Quantitative Evidence for Altered Mesenchymal Stem Cell Remodeling of Collagen in an Oxidative Environment—Peculiar Effect of Epigallocatechin-3-Gallate
Published in Polymers (22-09-2022)“…Mesenchymal stem cells (MSCs) are involved in the process of extracellular matrix (ECM) remodeling where collagens play a pivotal role. We recently…”
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Dynamic culture of mesenchymal stem cells on thermo-responsive PNIPAM substrate
Published in Frontiers in bioengineering and biotechnology (2016)“…Abstract only…”
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