Search Results - "Alsubaiyel, Amal M."

Development a novel robust method to enhance the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug based on machine-learning by Abdelbasset, Walid Kamal, Elkholi, Safaa M., Ismail, Khadiga Ahmed, Alshehri, Sameer, Alobaida, Ahmed, Huwaimel, Bader, Alatawi, Ahmed D., Alsubaiyel, Amal M., Venkatesan, Kumar, Abourehab, Mohammed A. S.

“…Accurate specification of the drugs’ solubility is known as an important activity to appropriately manage the supercritical impregnation process. Over the last…”
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Optimization of tamoxifen solubility in carbon dioxide supercritical fluid and investigating other molecular targets using advanced artificial intelligence models by Alshahrani, Saad M., Alshetaili, Abdullah S., Alfadhel, Munerah M., Belal, Amany, Abourehab, Mohammad A. S., Al Saqr, Ahmed, Almutairy, Bjad K., Venkatesan, Kumar, Alsubaiyel, Amal M., Pishnamazi, Mahboubeh

“…Particle size, shape and morphology can be considered as the most significant functional parameters, their effects on increasing the performance of oral solid…”
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Design of predictive model to optimize the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug by Alshehri, Sameer, Alqarni, Mohammed, Namazi, Nader Ibrahim, Naguib, Ibrahim A., Venkatesan, Kumar, Mosaad, Yasser O., Pishnamazi, Mahboubeh, Alsubaiyel, Amal M., Abourehab, Mohammed A. S.

“…These days, many efforts have been made to increase and develop the solubility and bioavailability of novel therapeutic medicines. One of the most believable…”
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Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization by Alqarni, Mohammed, Namazi, Nader Ibrahim, Alshehri, Sameer, Naguib, Ibrahim A, Alsubaiyel, Amal M, Venkatesan, Kumar, Elmokadem, Eman Mohamed, Pishnamazi, Mahboubeh, Abourehab, Mohammed A S

“…Industrial-based application of supercritical CO (SCCO ) has emerged as a promising technology in numerous scientific fields due to offering brilliant…”
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Author Correction: Optimization of tamoxifen solubility in carbon dioxide supercritical fluid and investigating other molecular targets using advanced artificial intelligence models by Alshahrani, Saad M., Alshetaili, Abdullah S., Alfadhel, Munerah M., Belal, Amany, Abourehab, Mohammad A. S., Al Saqr, Ahmed, Almutairy, Bjad K., Venkatesan, Kumar, Alsubaiyel, Amal M., Pishnamazi, Mahboubeh

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Development of GBRT Model as a Novel and Robust Mathematical Model to Predict and Optimize the Solubility of Decitabine as an Anti-Cancer Drug by Abdelbasset, Walid Kamal, Elsayed, Shereen H, Alshehri, Sameer, Huwaimel, Bader, Alobaida, Ahmed, Alsubaiyel, Amal M, Alqahtani, Abdulsalam A, El Hamd, Mohamed A, Venkatesan, Kumar, AboRas, Kareem M, Abourehab, Mohammed A. S

“…The efficient production of solid-dosage oral formulations using eco-friendly supercritical solvents is known as a breakthrough technology towards developing…”
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Computational simulation and target prediction studies of solubility optimization of decitabine through supercritical solvent by Alshahrani, Saad M., Almutairy, Bjad K., Alfadhel, Munerah M., Belal, Amany, Abourehab, Mohammed A. S., Saqr, Ahmed Al, Alshetaili, Abdullah S., Venkatesan, Kumar, Alsubaiyel, Amal M., Pishnamazi, Mahboubeh

“…Computational analysis of drug solubility was carried out using machine learning approach. The solubility of Decitabine as model drug in supercritical CO 2 was…”
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Application of CO2 Supercritical Fluid to Optimize the Solubility of Oxaprozin: Development of Novel Machine Learning Predictive Models by Alshahrani, Saad M., Saqr, Ahmed Al, Alfadhel, Munerah M., Alshetaili, Abdullah S., Almutairy, Bjad K., Alsubaiyel, Amal M., Almari, Ali H., Alamoudi, Jawaher Abdullah, Abourehab, Mohammed A. S.

“…Over the last years, extensive motivation has emerged towards the application of supercritical carbon dioxide (SCCO2) for particle engineering. SCCO2 has great…”
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Design and optimization of ganciclovir solid dispersion for improving its bioavailability by Gaber, Dalia A., Alnwiser, Manar A., Alotaibi, Nadia L., Almutairi, Rawan A., Alsaeed, Sumaih S., Abdoun, Siham A., Alsubaiyel, Amal M.

“…Development of new approaches for oral delivery of an existing antiviral drug aimed to enhance its permeability and hence bioavailability. Ganciclovir (GC) is…”
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Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis by Eissa, Essam M., Elkomy, Mohammed H., Eid, Hussein M., Ali, Adel A., Abourehab, Mohammed A. S., Alsubaiyel, Amal M., Naguib, Ibrahim A., Alsalahat, Izzeddin, Hassan, Amira H.

“…This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate…”
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Synthesized nano particles of glimepiride via spray freezing into cryogenic liquid: characterization, antidiabetic activity, and bioavailability by Gaber, Dalia A., Alhuwaymili, Abdulrahman S., Alhawas, Hessah S., Almutiri, Alhnouf A., Alsubaiyel, Amal M., Abdoun, Siham A., Almutairi, Reem A.

“…The aim of this work was to formulate glimepiride (class II drug) which is characterized by low solubility and high permeability as nanostructured particles…”
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Computational exploration and design of a multi-epitopes vaccine construct against Chlamydia psittaci by Alsubaiyel, Amal M., Bukhari, Sarah I.

“…Chlamydia psittaci is an intracellular pathogen and causes variety of deadly infections in humans. Antibiotics are effective against C. psittaci however high…”
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Measurement of metoprolol solubility in supercritical carbon dioxide; experimental and modeling study by Alshahrani, Saad M., Alsubaiyel, Amal M., Abduljabbar, Maram H., Abourehab, Mohammed A.S.

“…Metoprolol is a beta-blocker agent, widely used to treat hypertension, and some heart diseases. However, due to low bioavailability and short half-life of this…”
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DFT study of carboplatin encapsulation interactions with carboxylated carbon nanotubes and conjugated to folic acid for targeted nano delivery systems by Hani, Umme, Huwaimel, Bader, Alsubaiyel, Amal M., Alshahrani, Saad M., Alshammari, Farhan, Alanazi, Jowaher, Alanazi, Muteb, Alharby, Tareq Nafea

“…In this study, a nano-drug delivery design based on (8, 8) carboxylated single-walled carbon nanotube (CNT-COOH) and folic acid (FA) decorated on CNT-COOH…”
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Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies by Allemailem, Khaled S, Almatroudi, Ahmad, Rahmani, Arshad Husain, Alrumaihi, Faris, Alradhi, Arwa Essa, Alsubaiyel, Amal M, Algahtani, Mohammad, Almousa, Rand Mohammad, Mahzari, Ali, Sindi, Abdulmajeed A A, Dobie, Gasim, Khan, Amjad Ali

“…The genome editing approach by clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein 9 (CRISPR/Cas9) is a revolutionary…”
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Novel and accurate mathematical simulation of various models for accurate prediction of surface tension parameters through ionic liquids by Obaid, Rami J., Kotb, Hossam, Alsubaiyel, Amal M., Uddin, Jalal, Sani Sarjad, Mohd, Lutfor Rahman, Md, Ahmed, Saleh A.

“…Ionic Liquids (ILs) as a novel class of liquid solvent simultaneously carry the positive characteristics of both molten saltsand organic liquids. Remarkable…”
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Experimental - Theoretical approach for determination of Metformin solubility in supercritical carbon dioxide: Thermodynamic modeling by Venkatesan, Kumar, Alshahrani, Saad M., Alsubaiyel, Amal M., Abduljabbar, Maram H., Alosaimi, Manal E., Grishina, Maria, Shirazian, Saeed

“…Metformin, as an anti-hyperglycemic, is the main medicine for treating diabetes of type II. However, its daily dose is high due to its incomplete absorption…”
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Nano-Emulsion Based Gel for Topical Delivery of an Anti-Inflammatory Drug: In vitro and in vivo Evaluation by Gaber, Dalia A, Alsubaiyel, Amal M, Alabdulrahim, Alanoud K, Alharbi, Hanan Z, Aldubaikhy, Rama M, Alharbi, Rawan S, Albishr, Wades K, Mohamed, Heba A

“…Arthritic disorder is a common disease in elderly patients and the most common cause of joint dysfunction. This study aims to design Piroxicam-loaded…”
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Solubility enhancement of decitabine as anticancer drug via green chemistry solvent: Novel computational prediction and optimization by Namazi, Nader Ibrahim, Alshehri, Sameer, Bafail, Rawan, Huwaimel, Bader, Alsubaiyel, Amal M., Alamri, Ali H., Alatawi, Ahmed D., Kotb, Hossam, Sarjadi, Mohd Sani, Rahman, Md. Lutfor, Abourehab, Mohammed A.S.

“…Nowadays, supercritical fluid technology (SFT) has been an interesting scientific subject in disparate industrial-based activities such as drug delivery,…”
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A robust computational investigation on C60 fullerene nanostructure as a novel sensor to detect SCN by Alshahrani, Saad M., Alshehri, Sameer, Alsubaiyel, Amal M., Alzhrani, Rami M., Alatawi, Ahmed D., Algarni, Majed Ahmed, Abduljabbar, Maram H., Ng Kay Lup, Andrew, Sarjad, Mohd Sani, Rahman, Md. Lutfor, Abourehab, Mohammed A.S.

“…This study explored on the adsorption properties and electronic structure of SCN− via density functional theory analysis on the exterior surfaces of C60 and…”
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