Search Results - "Alsubait, Arwa"
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Blockade of p38 MAPK overcomes AML stem cell line KG1a resistance to 5-Fluorouridine and the impact on miRNA profiling
Published in PloS one (05-05-2022)“…Most of the AML patients in remission develop multidrug resistance after the first-line therapy and relapse. AML stem cells have gained attention for their…”
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Journal Article -
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Exploring the potential of Ziziphus nummularia and luteolin-7-O-glucoside as tubulin inhibitors in cancer therapy and survival
Published in Scientific reports (26-03-2024)“…Cancer is responsible for approximately 10 million deaths worldwide, with 70% of the deaths occurring in low- and middle-income countries; as such safer and…”
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Journal Article -
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The Impact of COVID-19 Infection on Patients with Chronic Diseases Admitted to ICU: a Cohort Retrospective Study
Published in Journal of Epidemiology and Global Health (01-06-2023)“…The coronavirus disease (COVID-19) infection is causing significant morbidity and mortality rates worldwide. A comprehensive investigation of the disease…”
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Journal Article -
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Congenital disorder of glycosylation with defective fucosylation 2 (FCSK gene defect): The third report in the literature with a mild phenotype
Published in Molecular genetics & genomic medicine (01-04-2023)“…Background Congenital disorders of glycosylation (CDG) are a group of heterogeneous disorders caused by abnormal lipid or protein glycosylation. Variants in…”
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Journal Article -
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Hemoglobinopathy correction with CRISPR or not; gene therapy is the solution
Published in Journal of nature and science of medicine (01-01-2020)“…Hemoglobin (Hb) disorders or hemoglobinopathies are groups of blood conditions involving inherited genetic diseases – mostly as single-gene autosomal recessive…”
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Journal Article -
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CYP1B1 gene: Implications in glaucoma and cancer
Published in Journal of Cancer (01-01-2020)“…Glaucoma is a serious disease that can lead to irreversible loss of vision. Patients with primary congenital glaucoma may have elevated intraocular pressure…”
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Journal Article Book Review -
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Abstract P2-21-11: A high content imaging and analysis approach to screen compounds for novel drug targets in 3D breast cancer co-culture model
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Abstract The desired effect of cancer therapeutics can only be conceived when applied to complex multicellular structures with different cell types and…”
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Journal Article -
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Understanding the Molecular Basis of Human Craniofacial Disorders Using Caenorhabditis elegans as a Model Organism
Published 01-01-2019“…Twist family members are highly conserved basic helix-loop-helix (bHLH) transcription factors that are important for mesoderm development in all animals. Twist…”
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Dissertation -
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Airborne transmission of SARS-CoV-2 is the dominant route of transmission: droplets and aerosols
Published in Le infezioni in medicina (01-03-2021)“…Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic worldwide. On a daily basis…”
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Journal Article -
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Localized TWIST1 and TWIST2 basic domain substitutions cause four distinct human diseases that can be modeled in Caenorhabditis elegans
Published in Human molecular genetics (01-06-2017)“…Twist transcription factors, members of the basic helix-loop-helix family, play crucial roles in mesoderm development in all animals. Humans have two…”
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Journal Article