Search Results - "Alsop, Eric"

Complementary Microorganisms in Highly Corrosive Biofilms from an Offshore Oil Production Facility by Vigneron, Adrien, Alsop, Eric B, Chambers, Brian, Lomans, Bartholomeus P, Head, Ian M, Tsesmetzis, Nicolas

“…Offshore oil production facilities are frequently victims of internal piping corrosion, potentially leading to human and environmental risks and significant…”
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Succession in the petroleum reservoir microbiome through an oil field production lifecycle by Vigneron, Adrien, Alsop, Eric B, Lomans, Bartholomeus P, Kyrpides, Nikos C, Head, Ian M, Tsesmetzis, Nicolas

“…Subsurface petroleum reservoirs are an important component of the deep biosphere where indigenous microorganisms live under extreme conditions and in isolation…”
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Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo by Bouchareychas, Laura, Duong, Phat, Covarrubias, Sergio, Alsop, Eric, Phu, Tuan Anh, Chung, Allen, Gomes, Michael, Wong, David, Meechoovet, Bessie, Capili, Allyson, Yamamoto, Ryo, Nakauchi, Hiromitsu, McManus, Michael T., Carpenter, Susan, Van Keuren-Jensen, Kendall, Raffai, Robert L.

“…Developing strategies that promote the resolution of vascular inflammation and atherosclerosis remains a major therapeutic challenge. Here, we show that…”
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Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum by Gittings, Lauren M., Alsop, Eric B., Antone, Jerry, Singer, Mo, Whitsett, Timothy G., Sattler, Rita, Van Keuren-Jensen, Kendall

“…The C9ORF72 -linked diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are characterized by the nuclear depletion and cytoplasmic…”
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Coordinating environmental genomics and geochemistry reveals metabolic transitions in a hot spring ecosystem by Swingley, Wesley D, Meyer-Dombard, D'Arcy R, Shock, Everett L, Alsop, Eric B, Falenski, Heinz D, Havig, Jeff R, Raymond, Jason

“…We have constructed a conceptual model of biogeochemical cycles and metabolic and microbial community shifts within a hot spring ecosystem via coordinated…”
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Evaluation of commercially available small RNASeq library preparation kits using low input RNA by Yeri, Ashish, Courtright, Amanda, Danielson, Kirsty, Hutchins, Elizabeth, Alsop, Eric, Carlson, Elizabeth, Hsieh, Michael, Ziegler, Olivia, Das, Avash, Shah, Ravi V, Rozowsky, Joel, Das, Saumya, Van Keuren-Jensen, Kendall

“…Evolving interest in comprehensively profiling the full range of small RNAs present in small tissue biopsies and in circulating biofluids, and how the profile…”
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Resolving prokaryotic taxonomy without rRNA: longer oligonucleotide word lengths improve genome and metagenome taxonomic classification by Alsop, Eric B, Raymond, Jason

“…Oligonucleotide signatures, especially tetranucleotide signatures, have been used as method for homology binning by exploiting an organism's inherent biases…”
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ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD by Moore, Stephen, Alsop, Eric, Lorenzini, Ileana, Starr, Alexander, Rabichow, Benjamin E., Mendez, Emily, Levy, Jennifer L., Burciu, Camelia, Reiman, Rebecca, Chew, Jeannie, Belzil, Veronique V., W. Dickson, Dennis, Robertson, Janice, Staats, Kim A., Ichida, Justin K., Petrucelli, Leonard, Van Keuren-Jensen, Kendall, Sattler, Rita

“…The hexanucleotide repeat expansion GGGGCC (G 4 C 2 ) n in the C9orf72 gene is the most common genetic abnormality associated with amyotrophic lateral…”
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Comparative metagenomics of hydrocarbon and methane seeps of the Gulf of Mexico by Vigneron, Adrien, Alsop, Eric B., Cruaud, Perrine, Philibert, Gwenaelle, King, Benjamin, Baksmaty, Leslie, Lavallée, David, P. Lomans, Bartholomeus, Kyrpides, Nikos C., Head, Ian M., Tsesmetzis, Nicolas

“…Oil and gas percolate profusely through the sediments of the Gulf of Mexico, leading to numerous seeps at the seafloor, where complex microbial, and sometimes…”
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Cryopreservation of cerebrospinal fluid cells preserves the transcriptional landscape for single-cell analysis by Kodali, Mahesh Chandra, Antone, Jerry, Alsop, Eric, Jayakumar, Rojashree, Parikh, Khushi, Chiot, Aude, Sanchez-Molina, Paula, Ajami, Bahareh, Arnold, Steven E, Jensen, Kendall, Das, Sudeshna, Weinberg, Marc S

“…Cerebrospinal fluid (CSF) matrix biomarkers have become increasingly valuable surrogate markers of neuropsychiatric diseases in research and clinical practice…”
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Single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease by Wang, Qi, Antone, Jerry, Alsop, Eric, Reiman, Rebecca, Funk, Cory, Bendl, Jaroslav, Dudley, Joel T., Liang, Winnie S., Karr, Timothy L., Roussos, Panos, Bennett, David A., De Jager, Philip L., Serrano, Geidy E., Beach, Thomas G., Van Keuren-Jensen, Kendall, Mastroeni, Diego, Reiman, Eric M., Readhead, Benjamin P.

“…The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the study of Alzheimer’s disease (AD). Integration with complementary…”
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Microbial community analysis of three hydrocarbon reservoir cores provides valuable insights for the assessment of reservoir souring potential by Tsesmetzis, Nicolas, Alsop, Eric B., Vigneron, Adrien, Marcelis, Fons, Head, Ian M., Lomans, Bart P.

“…Three hydrocarbon reservoir cores were obtained from a high temperature non-waterflooded offshore reservoir. All three cores were taken from a 56-m section of…”
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Microbial and Isotopic Evidence for Methane Cycling in Hydrocarbon-Containing Groundwater from the Pennsylvania Region by Vigneron, Adrien, Bishop, Andrew, Alsop, Eric B, Hull, Kellie, Rhodes, Ileana, Hendricks, Robert, Head, Ian M, Tsesmetzis, Nicolas

“…The Pennsylvania region hosts numerous oil and gas reservoirs and the presence of hydrocarbons in groundwater has been locally observed. However, these…”
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Merging metagenomics and geochemistry reveals environmental controls on biological diversity and evolution by Alsop, Eric B, Boyd, Eric S, Raymond, Jason

“…BACKGROUND: The metabolic strategies employed by microbes inhabiting natural systems are, in large part, dictated by the physical and geochemical properties of…”
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High glucose macrophage exosomes enhance atherosclerosis by driving cellular proliferation & hematopoiesis by Bouchareychas, Laura, Duong, Phat, Phu, Tuan Anh, Alsop, Eric, Meechoovet, Bessie, Reiman, Rebecca, Ng, Martin, Yamamoto, Ryo, Nakauchi, Hiromitsu, Gasper, Warren J., Van Keuren-Jensen, Kendall, Raffai, Robert L.

“…We investigated whether extracellular vesicles (EVs) produced under hyperglycemic conditions could communicate signaling to drive atherosclerosis. We did so by…”
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Moderate intrinsic phenotypic alterations in C9orf72 ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features by Lorenzini, Ileana, Alsop, Eric, Levy, Jennifer, Gittings, Lauren M, Lall, Deepti, Rabichow, Benjamin E, Moore, Stephen, Pevey, Ryan, Bustos, Lynette M, Burciu, Camelia, Bhatia, Divya, Singer, Mo, Saul, Justin, McQuade, Amanda, Tzioras, Makis, Mota, Thomas A, Logemann, Amber, Rose, Jamie, Almeida, Sandra, Gao, Fen-Biao, Marks, Michael, Donnelly, Christopher J, Hutchins, Elizabeth, Hung, Shu-Ting, Ichida, Justin, Bowser, Robert, Spires-Jones, Tara, Blurton-Jones, Mathew, Gendron, Tania F, Baloh, Robert H, Van Keuren-Jensen, Kendall, Sattler, Rita

“…While motor and cortical neurons are affected in amyotrophic lateral sclerosis and frontotemporal dementia (ALS/FTD), it remains largely unknown if and how…”
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Extracellular microRNAs in blood differentiate between ischaemic and haemorrhagic stroke subtypes by Kalani, M. Yashar S., Alsop, Eric, Meechoovet, Bessie, Beecroft, Taylor, Agrawal, Komal, Whitsett, Timothy G., Huentelman, Matthew J., Spetzler, Robert F., Nakaji, Peter, Kim, Seungchan, Van Keuren-Jensen, Kendall

“…Rapid identification of patients suffering from cerebral ischaemia, while excluding intracerebral haemorrhage, can assist with patient triage and expand…”
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Small RNA Changes in Plasma Have Potential for Early Diagnosis of Alzheimer's Disease before Symptom Onset by Palade, Joanna, Alsop, Eric, Courtright-Lim, Amanda, Hsieh, Michael, Whitsett, Timothy G, Galasko, Douglas, Van Keuren-Jensen, Kendall

“…Alzheimer's disease (AD), due to its multifactorial nature and complex etiology, poses challenges for research, diagnosis, and treatment, and impacts millions…”
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Contrasting Pathways for Anaerobic Methane Oxidation in Gulf of Mexico Cold Seep Sediments by Vigneron, Adrien, Alsop, Eric B, Cruaud, Perrine, Philibert, Gwenaelle, King, Benjamin, Baksmaty, Leslie, Lavallee, David, Lomans, Bartholomeus P, Eloe-Fadrosh, Emiley, Kyrpides, Nikos C, Head, Ian M, Tsesmetzis, Nicolas

“…Gulf of Mexico sediments harbor numerous hydrocarbon seeps associated with high sedimentation rates and thermal maturation of organic matter. These ecosystems…”
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Biological basis of extensive pleiotropy between blood traits and cancer risk by Pardo-Cea, Miguel Angel, Farré, Xavier, Esteve, Anna, Palade, Joanna, Espín, Roderic, Mateo, Francesca, Alsop, Eric, Alorda, Marc, Blay, Natalia, Baiges, Alexandra, Shabbir, Arzoo, Comellas, Francesc, Gómez, Antonio, Arnan, Montserrat, Teulé, Alex, Salinas, Monica, Berrocal, Laura, Brunet, Joan, Rofes, Paula, Lázaro, Conxi, Conesa, Miquel, Rojas, Juan Jose, Velten, Lars, Fendler, Wojciech, Smyczynska, Urszula, Chowdhury, Dipanjan, Zeng, Yong, He, Housheng Hansen, Li, Rong, Van Keuren-Jensen, Kendall, de Cid, Rafael, Pujana, Miquel Angel

“…The immune system has a central role in preventing carcinogenesis. Alteration of systemic immune cell levels may increase cancer risk. However, the extent to…”
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