Search Results - "Alsop, D.C."

Evaluation of the Sensitivity of Inhomogeneous Magnetization Transfer (ihMT) MRI for Multiple Sclerosis by Van Obberghen, E, Mchinda, S, le Troter, A, Prevost, V H, Viout, P, Guye, M, Varma, G, Alsop, D C, Ranjeva, J-P, Pelletier, J, Girard, O, Duhamel, G

“…Inhomogeneous magnetization transfer is a new endogenous MR imaging contrast mechanism that has demonstrated high specificity for myelin. Here, we tested the…”
Get full text

Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study by Stankiewicz, J.M, Neema, M, Alsop, D.C, Healy, B.C, Arora, A, Buckle, G.J, Chitnis, T, Guttmann, C.R.G, Hackney, D, Bakshi, R

“…Abstract Objective Assess the relationship between spinal cord T2 hyperintense lesions and clinical status in multiple sclerosis (MS) with 1.5 and 3 T MRI…”
Get full text

Resting-state cerebral blood flow in amygdala is modulated by sex and serotonin transporter genotype by El-Hage, W., Zelaya, F., Radua, J., Gohier, B., Alsop, D.C., Phillips, M.L., Surguladze, S.A.

“…Serotonin transporter-linked polymorphic region (5-HTTLPR) has been associated with modulation of resting-state amygdala level, which was considered to…”
Get full text

Validating the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI to myelin with fluorescence microscopy by Duhamel, G., Prevost, V.H., Cayre, M., Hertanu, A., Mchinda, S., Carvalho, V.N., Varma, G., Durbec, P., Alsop, D.C., Girard, O.M.

“…Inhomogeneous Magnetization Transfer (ihMT) is a development from the MT MRI technique. IhMT can be considered as a dipolar order relaxation time (T1D)…”
Get full text

Pharmacological manipulation of neurotransmitter activity induces disparate effects on cerebral blood flow and resting-state fluctuations by Munsch, F., Taso, M., Wolf, D.H., Press, D., Buss, S., Detre, J.A., Alsop, D.C.

“…Abstract Functional MRI methods can assess aspects of drug-induced brain response. Resting blood oxygenation level dependent (BOLD) fMRI and arterial spin…”
Get full text

Interpretation of magnetization transfer from inhomogeneously broadened lines (ihMT) in tissues as a dipolar order effect within motion restricted molecules by Varma, G., Girard, O.M., Prevost, V.H., Grant, A.K., Duhamel, G., Alsop, D.C.

“…[Display omitted] •Inclusion of a dipolar reservoir in quantitative MT allows modeling of the ihMT signal.•Differential effects of single vs. dual saturation…”
Get full text

Low duty-cycle pulsed irradiation reduces magnetization transfer and increases the inhomogeneous magnetization transfer effect by Varma, G., Girard, O.M., Mchinda, S., Prevost, V.H., Grant, A.K., Duhamel, G., Alsop, D.C.

“…[Display omitted] •Reduced RF duty-cycle strongly affects some MT phenomena.•Brain tissue ihMT increased up to 3 fold going from a 50% to 5% duty-cycle.•Muscle…”
Get full text

Optimization of inhomogeneous magnetization transfer (ihMT) MRI contrast for preclinical studies using dipolar relaxation time (T1D) filtering by Prevost, V.H., Girard, O.M., Mchinda, S., Varma, G., Alsop, D.C., Duhamel, G.

“…A pulsed inhomogeneous magnetization transfer (ihMT)‐prepared fast imaging sequence was implemented at 11.75 T for preclinical studies on mouse central nervous…”
Get full text

Experimental Design and the Relative Sensitivity of BOLD and Perfusion fMRI by Aguirre, G.K., Detre, J.A., Zarahn, E., Alsop, D.C.

“…This paper compares the statistical power of BOLD and arterial spin labeling perfusion fMRI for a variety of experimental designs within and across subjects…”
Get full text

Simultaneous PML-IRIS after discontinuation of natalizumab in a patient with MS by GHEUENS, S, SMITH, D. R, WANG, X, ALSOP, D. C, LENKINSKI, R. E, KORALNIK, I. J

“…Progressive multifocal leukoencephalopathy (PML) is a severe complication of natalizumab therapy in patients with multiple sclerosis (MS), which is often…”
Get full text

A 3T MR Imaging Investigation of the Topography of Whole Spinal Cord Atrophy in Multiple Sclerosis by KLEIN, J. P, ARORA, A, HOUTCHENS, M. K, CECCARELLI, A, DELL'OGLIO, E, GUTTMANN, C. R. G, ALSOP, D. C, HACKNEY, D. B, BAKSHI, R, NEEMA, M, HEALY, B. C, TAUHID, S, GOLDBERG-ZIMRING, D, CHAVARRO-NIETO, C, STANKIEWICZ, J. M, COHEN, A. B, BUCKLE, G. J

“…Spinal cord atrophy is a common feature of MS. However, it is unknown which cord levels are most susceptible to atrophy. We performed whole cord imaging to…”
Get full text

Personality factors correlate with regional cerebral perfusion by O'Gorman, R.L., Kumari, V., Williams, S.C.R., Zelaya, F.O., Connor, S.E.J., Alsop, D.C., Gray, J.A.

“…There is an increasing body of evidence pointing to a neurobiological basis of personality. The purpose of this study was to investigate the biological bases…”
Get full text

A functional MRI study of mental image generation by D'Esposito, M, Detre, J.A, Aguirre, G.K, Stallcup, M, Alsop, D.C, Tippet, L.J, Farah, M.J

“…The neural substrates of mental image generation were investigated with functional MRI. Subjects listened to words under two different instructional…”
Get full text

Empirical validation of SPM for functional MRI by Aguirre, G.K., Zarahn, E, Detre, J.A., Alsop, D.C., D'Esposito, M

Get full text

The shape of the fMRI response in primary sensori-motor regions to varying rates of a simple reaction time task by Zarahn, E, Aguirre, G.K., Detre, J.A., Alsop, D.C., D'Esposito, M.

Get full text

The parahippocampus subserves topographical learning in man by Aguirre, G.K., Detre, J.A., Alsop, D.C., D'Esposito, M.

Get full text

Analysis of multi-subject “noise” fMRI data with SPM by Zarahn, E, Aguirre, G.K., Detre, J.A., Alsop, D.C., D'Esposito, M.

Get full text

Transit time analysis of BOLD imaging data by Maccotta, L, Aguirre, G.K., Zarahn, E., Alsop, D.C., D'Esposito, M., Detre, J.A.

Get full text

Effects of cognitive processing time on fMRI activity by D'esposito, M, Zarahn, E, Aguirre, G.K., Shin, R.K., Auerbach, P, Thompson, C, Alsop, D.C., Detre, J.A.

Get full text

Functional Activation During Material Specific Memory Encoding by Killgore, W.D.S., Glosser, G., Alsop, D.C., Cooke, A.N., McSorley, C., Grossman, M., Detre, J.A.

Get full text