Search Results - "Alshemmari, Salem H"
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Prognostic impact of chronic lymphocytic leukemia comorbidity index in a young population: a real-world evidence study of a national gulf region cohort
Published in BMC cancer (13-05-2024)“…In chronic lymphocytic leukaemia (CLL), comorbidities assessed by the CLL comorbidity index (CLL-CI) have been associated with outcomes in Western cohorts. We…”
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A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency
Published in Nature genetics (01-01-2016)“…Raif Geha, Louis Kunkel, Waleed Al-Herz and colleagues report a mutation in TFRC (encoding transferrin receptor 1, TfR1) that causes combined immunodeficiency…”
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3
Chronic lymphocytic leukemia in a young population
Published in Leukemia research (01-11-2021)“…•The incidence of CLL in Kuwait is rare, with an annual incidence is 0.4 per 100,000.•There are some biological differences in CLL to what has been published,…”
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UPLC-Tandem Mass Spectrometry for Quantification of Busulfan in Human Plasma: Application to Therapeutic Drug Monitoring
Published in Scientific reports (02-06-2020)“…Busulfan (Bu) is an alkylating agent commonly used in preparative regimens for hematologic malignant and non-malignant patients undergoing hematopoietic stem…”
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Evaluation of the CLL-IPI and IPS-E Prognostic Indices in a Young Middle Eastern Population with Chronic Lymphocytic Leukemia: A Retrospective Analysis at the Kuwait Cancer Control Center
Published in Medical principles and practice (01-10-2023)“…Introduction: The Chronic Lymphocytic Leukemia International Prognostic Index (CLL-IPI) is a powerful prognostic tool validated in multiple Western…”
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Prognosis and Outcome of Fit Patients with Acute Myeloid Leukemia in Kuwait
Published in Clinical lymphoma, myeloma and leukemia (01-09-2021)“…Acute myeloid leukemia (AML) data from the Middle East are limited to single-center studies. We report leukemia-free survival (LFS) and overall survival (OS)…”
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Analysis of Common Driver Mutations in Philadelphia-Negative Myeloproliferative Neoplasms
Published in Clinical lymphoma, myeloma and leukemia (01-07-2021)“…Philadelphia-negative myeloproliferative neoplasms (MPNs) are a group of hematopoietic stem cell disorders that include polycythemia vera (PV), essential…”
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Evidence-Based Management of Chronic Lymphocytic Leukemia: Consensus Statements from the Gulf Region
Published in Acta haematologica (2024)“…Despite recent advances in diagnosis, prognostication, and treatment options, chronic lymphocytic leukemia (CLL) is still a largely incurable disease. New…”
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Epidemiology of de novo Acute Myeloid Leukemia in Kuwait per the 2016 WHO Classification
Published in Medical principles and practice (01-07-2022)“…Objective: Acute myeloid leukemia (AML) is a hematological malignancy that arises from the clonal proliferation of immature myeloid cells. Although the number…”
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10
Molecular Pathogenesis and Clinical Significance of Driver Mutations in Primary Myelofibrosis: A Review
Published in Medical principles and practice (01-01-2016)“…Primary myelofibrosis (PMF) is a rare chronic BCR-ABL1-negative myeloproliferative neoplasm characterized by progressive bone marrow fibrosis, inefficient…”
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Association analysis of genetic variants in the ghrelin and tumor necrosis factor α genes and the risk for non-Hodgkin's lymphoma in Kuwaitis
Published in Cancer biomarkers : section A of Disease markers (01-01-2021)“…Non-Hodgkin's lymphoma (NHL) is the most common hematological malignancy in the world. Many etiologic factors have been implicated in the risk of developing…”
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JAK2V617F allele burden in patients with myeloproliferative neoplasms
Published in Annals of hematology (01-05-2014)“…Myeloproliferative neoplasms (MPNs) are clonal malignant diseases that represent a group of conditions including polycythemia vera (PV), essential…”
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Association of Genetic Polymorphisms in the VKORC1 and CYP2C9 Genes with Warfarin Dosage in a Group of Kuwaiti Individuals
Published in Molecular diagnosis & therapy (01-04-2016)“…Background and Objective Warfarin is the most widely prescribed oral anticoagulant worldwide. The narrow therapeutic index and the large variation in the…”
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The place of death of patients with cancer in Kuwait
Published in BMJ supportive & palliative care (01-12-2015)“…The place of death (PoD) has a significant effect on end-of-life care for patients dying of cancer. Little is known about the place of cancer deaths in our…”
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Genotypic and Phenotypic Differences between Nodal and Extranodal Diffuse Large B-Cell Lymphomas
Published in The journal of histochemistry and cytochemistry (01-10-2011)“…Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of diseases that have diverse clinical, pathological, and biological features. Here, it is shown…”
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Extranodal lymphoma: a comparative study
Published in Hematology (Luxembourg) (01-06-2008)“…The incidence of extranodal non-Hodgkin's lymphoma (NHL) is increasing worldwide. The epidemiology of NHL in the Middle East is largely unknown. We evaluated…”
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Representation of Expatriates Among Cancer Patients in Kuwait and the Need for Culturally-Competent Care
Published in Journal of psychosocial oncology (01-05-2012)“…From 2000 to 2007, 11,793 cancer patients received treatment in Kuwait. Non-Kuwaitis accounted for 6,016 (51%) patients. They came from 68 countries, mainly…”
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Performance status and deaths among children registered in Kuwait National Primary ImmunoDeficiency Disorders Registry
Published in Asian Pacific journal of allergy and immunology (01-06-2010)“…Children with primary immunodeficiency disorders (PIDD) have an increased risk of suffering from physical, social, and psychological problems. The aim of this…”
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Efficient identification of novel mutations in patients with limb girdle muscular dystrophy
Published in Neurogenetics (01-10-2010)“…Limb girdle muscular dystrophy type 2 (LGMD2) is a genetically heterogeneous autosomal recessive disorder caused by mutations in 15 known genes. DNA sequencing…”
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Factors Associated with Successful Mobilization of Progenitor Hematopoietic Stem Cells Among Patients with Lymphoid Malignancies
Published in Clinical lymphoma & myeloma (01-04-2008)“…This study's main aim was to assess the effect of 2 mobilization regimens (granulocyte colony-stimulating factor [G-CSF] and chemotherapy vs. G-CSF alone) on…”
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