Search Results - "Alshememry, Abdullah"
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Development and Evaluation of Chitosan Nanoparticles for Ocular Delivery of Tedizolid Phosphate
Published in Molecules (Basel, Switzerland) (04-04-2022)“…This study investigates the development of topically applied non-invasive chitosan-nanoparticles (CSNPs) for ocular delivery of tedizolid phosphate (TZP) for…”
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Recent nanotechnology advancements to treat multidrug-resistance pancreatic cancer: Pre-clinical and clinical overview
Published in Frontiers in pharmacology (24-08-2022)“…Pancreatic cancer (PC) remains one of the most lethal and incurable forms of cancer and has a poor prognosis. One of the significant therapeutic challenges in…”
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Iron Oxide Nanoparticles: Preparation, Characterization, and Assessment of Antimicrobial and Anticancer Activity
Published in Adsorption science & technology (2022)“…Nanotechnology and nanoparticles (NPs) have increasingly been studied as an alternative for antibiotics because of the feasibility to be used in implantable…”
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Perspectives of Positively Charged Nanocrystals of Tedizolid Phosphate as a Topical Ocular Application in Rabbits
Published in Molecules (Basel, Switzerland) (20-07-2022)“…The aim of this study was the successful utilization of the positively charged nanocrystals (NCs) of Tedizolid Phosphate (TZP) (0.1% w/v) for topical ocular…”
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Design and Development of D‒α‒Tocopheryl Polyethylene Glycol Succinate‒block‒Poly(ε-Caprolactone) (TPGS−b−PCL) Nanocarriers for Solubilization and Controlled Release of Paclitaxel
Published in Molecules (Basel, Switzerland) (04-05-2021)“…The objective of this study was to synthesize and characterize a set of biodegradable block copolymers based on TPGS-block-poly(ε-caprolactone) (TPGS-b-PCL)…”
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Polycaprolactone-Vitamin E TPGS Micellar Formulation for Oral Delivery of Paclitaxel
Published in Polymers (01-08-2024)“…This study aimed to investigate the potential of polycaprolactone-vitamin E TPGS (PCL-TPGS) micelles as a delivery system for oral administration of paclitaxel…”
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Sorafenib and Piperine co-loaded PLGA nanoparticles: Development, characterization, and anti-cancer activity against hepatocellular carcinoma cell line
Published in Saudi pharmaceutical journal (01-05-2024)“…Hepatocellular carcinoma (HCC) exhibits high mortality rates in the advanced stage (>90 %). Sorafenib (SORA) is a targeted therapy approved for the treatment…”
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ON-1 and BA-IX Are the Dominant Sub-Genotypes of Human Orthopneumovirus A&B in Riyadh, Saudi Arabia
Published in Genes (05-12-2022)“…(HOPV) is the major viral pathogen responsible for lower respiratory tract infections (LRTIs) in infants and young children in Riyadh, Saudi Arabia. Yet,…”
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Effect of amino acid composition of elastin‐like polypeptide nanoparticles on nonspecific protein adsorption, macrophage cell viability and phagocytosis
Published in Biopolymers (01-12-2021)“…Development of elastin‐like polypeptide (ELP) biomaterials is widespread, but information critical for clinical deployment is limited, with biocompatibility…”
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High-yield recombinant expression and purification of marginally soluble, short elastin-like polypeptides
Published in BioTechniques (01-12-2016)“…The protocol described here is designed as an extension of existing techniques for creating elastin-like polypeptides. It allows for the expression and…”
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Fabrication and Characterization of Tedizolid Phosphate Nanocrystals for Topical Ocular Application: Improved Solubilization and In Vitro Drug Release
Published in Pharmaceutics (23-06-2022)“…Positively charged NCs of TZP (0.1%, w/v) for ocular use were prepared by the antisolvent precipitation method. TZP is a novel 5-Hydroxymethyl-Oxazolidinone…”
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Development and Validation of UPLC–MS/MS Method for Quantitative Analysis of 5-Fluorouracil in Aqueous Humor of Rabbits
Published in Separations (01-06-2023)“…5-Fluorouracil (5-FU) is now used in eye drops for the management of conjunctival malignant melanoma, intraepithelial neoplasia, and corneal and conjunctival…”
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Solid Dispersions of Gefitinib with D-α-Tocopherol Polyethylene Glycol-1000 Succinate and 2-Hydroxypropyl β-Cyclodextrin Complex Improved Their Solubility, Dissolution and Apoptosis against A549 Cells
Published in Applied sciences (01-10-2023)“…This study focuses on the development and characterization of solid dispersions (SDs) of Gefitinib (GEF) to improve its aqueous solubility and therapeutic…”
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Thermoresponsive sol-gel improves ocular bioavailability of Dipivefrin hydrochloride and potentially reduces the elevated intraocular pressure in vivo
Published in Saudi pharmaceutical journal (01-08-2020)“…The present study involves the development of Dipivefrin hydrochloride (DV) containing Poloxamers (P407 and P188)-Carbopol-934 (CP) based thermoresponsive-gels…”
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Therapeutic benefits of quercetin in traumatic brain injury model exposed to cigarette smoke
Published in Saudi pharmaceutical journal (01-01-2024)“…Scientific evidences reported the deleterious effect of cigarette smoking or passive smoking on brain health particularly cognitive functions, blood–brain…”
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Bacteriophage carriers localize in the brain of a rat model of neonatal hypoxic‐ischemic encephalopathy
Published in Biotechnology journal (01-02-2022)“…Background Neonatal hypoxic‐ischemic encephalopathy arises from a reduction of oxygen and blood supply to the infant brain and can lead to severe brain damage…”
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The influence of demographics on influenza vaccine awareness and hesitancy among adults visiting educational hospital in Saudi Arabia
Published in Saudi pharmaceutical journal (01-02-2021)“…To understand the influence of demographics and education levels on awareness levels, and on the prevalence of hesitancy to receive the influenza vaccine among…”
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Self-assembly/disassembly hysteresis of nanoparticles composed of marginally soluble, short elastin-like polypeptides
Published in Journal of nanobiotechnology (17-02-2018)“…Elastin-like polypeptides (ELPs) are a fascinating biomaterial that has undergone copious development for a variety of therapeutic applications including as a…”
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Human plasma protein adsorption to elastinlike polypeptide nanoparticles
Published in Biointerphases (30-03-2020)“…Elastin-like polypeptides (ELPs) are being developed for numerous biomedical applications. There is a limited understanding of ELP biocompatibility, with…”
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Phytochemical analysis, antioxidant, anticancer, and antibacterial potential of Alpinia galanga (L.) rhizome
Published in Heliyon (15-09-2024)“…Alpinia galanga (L.) Willd. (A. galanga) is extremely significant and is utilized extensively in traditional medicine throughout many nations. This study aimed…”
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