Search Results - "Alshelh, Z."
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Disruption of default mode network dynamics in acute and chronic pain states
Published in NeuroImage clinical (01-01-2018)“…It has been proposed that pain competes with other attention-demanding stimuli for cognitive resources, and many chronic pain patients display significant…”
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Journal Article -
2
Altered regional brain T2 relaxation times in individuals with chronic orofacial neuropathic pain
Published in NeuroImage clinical (01-01-2018)“…The neural mechanisms underlying the development and maintenance of chronic pain following nerve injury remain unclear. There is growing evidence that chronic…”
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Journal Article -
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A Bayesian Neural Network-Based Method For The Extraction Of A Metabolite Corrected Arterial Input Function From Dynamic [11C]PBR28 PET
Published in 2023 IEEE Nuclear Science Symposium, Medical Imaging Conference and International Symposium on Room-Temperature Semiconductor Detectors (NSS MIC RTSD) (04-11-2023)“…In PET, arterial sampling and metabolite correction are prerequisites for the gold-standard measurement of values like the volume of distribution (V T ), often…”
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Conference Proceeding -
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The relationship between thalamic GABA content and resting cortical rhythm in neuropathic pain
Published in Human brain mapping (01-05-2018)“…Recurrent thalamocortical connections are integral to the generation of brain rhythms and it is thought that the inhibitory action of the thalamic reticular…”
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Journal Article -
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The pandemic brain: Neuroinflammation in non-infected individuals during the COVID-19 pandemic
Published in Brain, behavior, and immunity (01-05-2022)“…•Human study measuring pandemic-related neuroinflammation in individuals negative to COVID-19 antibodies.•Multimodal PET/MR brain imaging shows elevation in…”
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Journal Article -
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Altered Brainstem Pain-Modulation Circuitry Connectivity During Spontaneous Pain Intensity Fluctuations
Published in Journal of pain research (01-01-2020)“…Chronic pain, particularly that following nerve injury, can occur in the absence of external stimuli. Although the ongoing pain is sometimes continuous, in…”
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Journal Article -
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Effects of the glial modulator palmitoylethanolamide on chronic pain intensity and brain function
Published in Journal of pain research (01-08-2019)“…Chronic neuropathic pain (NP) is a complex disease that results from damage or presumed damage to the somatosensory nervous system. Current treatment regimens…”
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Journal Article -
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[11C]-PBR28 POSITRON EMISSION TOMOGRAPHY SIGNAL AS AN IMAGING BIOMARKER OF JOINT INFLAMMATION AND PAIN IN KNEE OSTEOATHRITIS
Published in Osteoarthritis imaging (2024)“…[11C]-PBR28 is a positron emission tomography (PET) radioligand targeting the 18-kDa translocator protein (TSPO). The expression of this protein is highly…”
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Journal Article