Search Results - "Alshekaili, Jalila"
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Circulating activated neutrophils in COVID-19: An independent predictor for mechanical ventilation and death
Published in International journal of infectious diseases (01-05-2021)“…•Neutrophil activation predicts critical illness in COVID-19.•Aberrant neutrophil response in COVID-19.•Activated neutrophils are a novel biomarker for…”
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A randomized trial of serological and cellular responses to hepatitis B vaccination in chronic kidney disease
Published in PloS one (10-10-2018)“…Chronic kidney disease (CKD) is associated with an increased risk of hepatitis B infection and impaired seroconversion to hepatitis B vaccine (HBV). Studies…”
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3
A Decade Experience on Severe Combined Immunodeficiency Phenotype in Oman, Bridging to Newborn Screening
Published in Frontiers in immunology (15-01-2021)“…Severe combined immunodeficiency (SCID) results from various monogenic defects that impair immune function and brings on early severe and life-threatening…”
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Immunological predictors of disease severity in patients with COVID-19
Published in International journal of infectious diseases (01-09-2021)“…•Predictors of COVID-19 severity will help prioritize resources and minimize mortality.•Immunological markers can be used as predictors of a poor…”
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Malformin-A1 (MA1) Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin-Induced Apoptosis
Published in Molecules (Basel, Switzerland) (13-06-2021)“…High-grade epithelial ovarian cancer is a fatal disease in women frequently associated with drug resistance and poor outcomes. We previously demonstrated that…”
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Immune Dysregulation in Monogenic Inborn Errors of Immunity in Oman: Over A Decade of Experience From a Single Tertiary Center
Published in Frontiers in immunology (06-04-2022)“…Inborn errors of immunity (IEIs) are being recognized as an important cause of morbidity and mortality in communities with a high frequency of consanguinity,…”
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Short and long-term immune changes in different severity groups of COVID-19 disease
Published in International journal of infectious diseases (01-09-2022)“…•Moderate and severe/critical groups had high inflammation at presentation.•Inflammation did not normalize for the severe/critical at 2 weeks.•Mild and…”
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8
STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles
Published in Scientific reports (23-02-2018)“…A subset of human follicular helper T cells (TFH) cells expresses CD57 for which no distinct function has been identified. We show that CD57+ TFH cells are…”
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Determination of an Aspergillus Fumigatus-Specific Immunoglobulin G Reference Range in an Adult Omani Population
Published in Sultan Qaboos University medical journal (01-02-2018)“…The presence of abnormally high levels of Aspergillus fumigatus-specific immunoglobulin (Ig) G antibodies can serve as a diagnostic criterion for severe…”
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10
Food allergen sensitisation patterns in Omani patients with allergic manifestations
Published in Sultan Qaboos University medical journal (01-11-2018)“…Objectives: This study aimed to evaluate the relationship between food allergen sensitisation patterns and allergic manifestations in Omani patients and…”
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11
TIM3 Is Upregulated in Cell Lysates of Patients with Acute Myeloid Leukemia
Published in Blood (15-11-2022)Get full text
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12
A homozygous loss-of-function C1S mutation is associated with Kikuchi-Fujimoto disease
Published in Clinical immunology (Orlando, Fla.) (01-07-2023)“…Kikuchi-Fujimoto disease (KFD) is a self-limited inflammatory disease of unknown pathogenesis. Familial cases have been described and defects in classical…”
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Clinical and Autoimmune Profiles of Omani Patients with True Versus False Positive Autoimmune Encephalitis Antibodies Panels
Published in Sultan Qaboos University medical journal (25-07-2024)“…The incidence of autoimmune encephalitis (AE) is rising due to increased awareness of the condition and detection of new autoantibodies. Coinciding with this…”
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14
Expression of JAK/STAT Signaling Proteins at Diagnosis and Remission in Patients with Acute Myeloid Leukemia
Published in Oman medical journal (30-05-2024)“…Objectives: Acute myeloid leukemia (AML), among other malignancies, has been linked to the deregulation of the Janus kinase/signal transducer and activator of…”
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15
Proteomics: Concepts and applications in human medicine
Published in World journal of biological chemistry (27-09-2021)“…Proteomics is the complete evaluation of the function and structure of proteins to understand an organism’s nature. Mass spectrometry is an essential tool that…”
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Interference with Immunoassays of a Neonate on High Biotin
Published in Oman medical journal (2023)Get full text
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17
Overlapping demyelinating syndrome (Neuromyelitis optica spectrum disorders NMOSD with anti-NMDA receptor encephalitis); A case report
Published in Multiple sclerosis and related disorders (01-07-2020)“…•Unusual and rare overlapping autoimmune syndrome reported in a young female.•Autoimmune syndromes, NMOSD and anti-NMDAR encephalitis presented with different…”
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Prevalence of coeliac disease in Omani adults with iron deficiency anaemia of unknown : cause case-finding study
Published in Sultan Qaboos University medical journal (01-05-2022)“…Objectives : This study aimed to estimate the serological prevalence of coeliac disease in patients with iron deficiency anaemia (IDA) of unknown cause at a…”
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19
Agammaglobulinaemia despite terminal B‐cell differentiation in a patient with a novel LRBA mutation
Published in Clinical & translational immunology (26-05-2017)“…Mutations in lipopolysaccharide‐responsive vesicle trafficking, beach and anchor‐containing protein (LRBA) cause immune deficiency and inflammation. Here, we…”
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Heterophile interference accounts for method-specific dsDNA antibodies in patients receiving anti-TNF treatment
Published in Rheumatology (Oxford, England) (01-05-2010)“…Objective. To evaluate analytical explanations for the highly reported incidence of antibodies to dsDNA in patients receiving TNF antagonists. Methods. Sixty…”
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