Search Results - "Alshehri, Sameer"
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In Vitro Evaluation and Biodistribution Studies of HPMA Copolymers Targeting the Gastrin Releasing Peptide Receptor in Prostate Cancer
Published in Pharmaceutical research (01-11-2020)“…Purpose The development of diagnostic and therapeutic agents utilizing small peptides (e.g., bombesin (BBN)) to target the overexpression of the…”
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Advanced modeling of pharmaceutical solubility in solvents using artificial intelligence techniques: assessment of drug candidate for nanonization processing
Published in Frontiers in medicine (22-07-2024)“…This research is an analysis of multiple regression models developed for predicting ketoprofen solubility in supercritical carbon dioxide under different…”
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A first-principles adsorption study of functionalized carbon, boron nitride, silicon carbon nanotubes with ifosfamide as vehicles for drug delivery: Thermal analysis
Published in Case studies in thermal engineering (01-11-2024)“…We investigated the adsorption of ifosfamide (IFS) on the outer surface of zigzag (10, 0) carbon nanotubes (CNT), boron nitride nanotubes (BNNT), and silicon…”
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Development a novel robust method to enhance the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug based on machine-learning
Published in Scientific reports (30-07-2022)“…Accurate specification of the drugs’ solubility is known as an important activity to appropriately manage the supercritical impregnation process. Over the last…”
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Fabrication, Characterization and Biomedical Evaluation of a Statistically Optimized Gelatin Scaffold Enriched with Co-Drugs Loaded into Controlled-Release Silica Nanoparticles
Published in Molecules (Basel, Switzerland) (01-07-2023)“…The current study focused on the fabrication of a well-designed, biocompatible, physically stable, non-irritating and highly porous gelatin scaffold loaded…”
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Novel numerical simulation of drug solubility in supercritical CO2 using machine learning technique: Lenalidomide case study
Published in Arabian journal of chemistry (01-11-2022)“…In pharmaceutical industry, finding promising ways to enhance the solubility of disparate types of drugs is an important challenge for the orally administered…”
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Adsorption of thiotepa on B12N12, Mg12O12, and Si12C12 fullerene-like cages: A DFT study
Published in Case studies in thermal engineering (01-11-2024)“…We examined the adsorption of thiotepa (TTP) on the outer surface of B12N12, Mg12O12, and Si12C12 fullerene-like cages using density functional theory (DFT)…”
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Design of predictive model to optimize the solubility of Oxaprozin as nonsteroidal anti-inflammatory drug
Published in Scientific reports (30-07-2022)“…These days, many efforts have been made to increase and develop the solubility and bioavailability of novel therapeutic medicines. One of the most believable…”
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Solubility Optimization of Loxoprofen as a Nonsteroidal Anti-Inflammatory Drug: Statistical Modeling and Optimization
Published in Molecules (Basel, Switzerland) (01-07-2022)“…Industrial-based application of supercritical CO (SCCO ) has emerged as a promising technology in numerous scientific fields due to offering brilliant…”
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Optimization of Fenoprofen solubility within green solvent through developing a novel and accurate GSO-GPR predictive model
Published in Arabian journal of chemistry (01-12-2022)“…Indisputable importance of drug solubility in various industrial perspectives has motivated the scientists to evaluate different techniques to improve it…”
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Application of Three Ecological Assessment Tools in Examining Chromatographic Methods for the Green Analysis of a Mixture of Dopamine, Serotonin, Glutamate and GABA: A Comparative Study
Published in Molecules (Basel, Switzerland) (07-09-2021)“…The assessment of greenness of analytical protocols is of great importance now to preserve the environment. Some studies have analyzed either only the…”
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Development of GBRT Model as a Novel and Robust Mathematical Model to Predict and Optimize the Solubility of Decitabine as an Anti-Cancer Drug
Published in Molecules (Basel, Switzerland) (01-09-2022)“…The efficient production of solid-dosage oral formulations using eco-friendly supercritical solvents is known as a breakthrough technology towards developing…”
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Fabrication, In Vitro, and In Vivo Assessment of Eucalyptol-Loaded Nanoemulgel as a Novel Paradigm for Wound Healing
Published in Pharmaceutics (01-09-2022)“…Wounds are the most common causes of mortality all over the world. Topical drug delivery systems are more efficient in treating wounds as compared to oral…”
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Biocompatibility and Hemolytic Activity Studies of Synthesized Alginate-Based Polyurethanes
Published in Polymers (20-05-2022)“…Many investigators have focused on the development of biocompatible polyurethanes by chemical reaction of functional groups contained in a spacer and…”
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Adsorption Potential of Schizophyllum commune White Rot Fungus for Degradation of Reactive Dye and Condition Optimization: A Thermodynamic and Kinetic Study
Published in Adsorption science & technology (2023)“…The pollution due to dyes from textile sector is one of the major issues faced worldwide. This study was focused on the removal of the reactive dye, Drimaren…”
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Nonsteroidal anti-inflammatory drug solubility optimization through green chemistry solvent: Artificial intelligence technique
Published in Case studies in thermal engineering (01-01-2024)“…This research paper presents a comprehensive thermodynamic and heat transfer study on predicting the ternary solubility of Nystatin in SC-CO2-Ethanol…”
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Heavy Metal Removal from Aqueous Effluents by TiO2 and ZnO Nanomaterials
Published in Adsorption Science & Technology (24-01-2023)“…The presence of heavy metals in wastewater, such as Ni, Pb, Cd, V, Cr, and Cu, is a serious environmental problem. This kind of inorganic pollutant is not…”
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Quality and In Vivo Assessment of a Fulvic Acid Complex: A Validation Study
Published in Scientia pharmaceutica (01-06-2022)“…The present work aimed to re-assess the bioavailability enhancement potential of fulvic acid (FA). Carbamazepine (CBZ) and peat were used as a model drug and…”
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Solubility enhancement of decitabine as anticancer drug via green chemistry solvent: Novel computational prediction and optimization
Published in Arabian journal of chemistry (01-12-2022)“…Nowadays, supercritical fluid technology (SFT) has been an interesting scientific subject in disparate industrial-based activities such as drug delivery,…”
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