Search Results - "Alshehri, Osama M."

Fibrin activates GPVI in human and mouse platelets by Alshehri, Osama M., Hughes, Craig E., Montague, Samantha, Watson, Stephanie K., Frampton, Jon, Bender, Markus, Watson, Steve P.

“…The glycoprotein VI (GPVI)-Fc receptor γ (FcRγ) chain is the major platelet signaling receptor for collagen. Paradoxically, in a FeCl3 injury model, occlusion,…”
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Synthesis, Molecular Docking, and Preclinical Evaluation of a New Succinimide Derivative for Cardioprotective, Hepatoprotective and Lipid-Lowering Effects by Qayyum, Muhammad Imran, Ullah, Sami, Rashid, Umer, Sadiq, Abdul, Obaidullah, Mahnashi, Mater H, Alshehri, Osama M, Jalal, Mohammed M, Alzahrani, Khalid J, Halawani, Ibrahim F

“…Cardiac and hepatotoxicities are major concerns in the development of new drugs. Better alternatives to other treatments are being sought to protect these…”
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Isolation, In Vitro and In Silico Anti-Alzheimer and Anti-Inflammatory Studies on Phytosteroids from Aerial Parts of Fragaria × ananassa Duch by Mahnashi, Mater H, Alshehri, Osama M

“…Based on the pharmacological importance of different species of fragaria, this research was carried out for the isolation of bioactive compounds from . Using…”
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Investigation of anti-nociceptive, anti-inflammatory potential and ADMET studies of pure compounds isolated from Isodon rugosus Wall. ex Benth by Alshehri, Osama M, Zeb, Anwar, Mukarram Shah, Syed Muhammad, Mahnashi, Mater H, Asiri, Saeed Ahmed, Alqahtani, Omaish, Sadiq, Abdul, Ibrar, Muhammad, Alshamrani, Saleh, Jan, Muhammad Saeed

“…The strong ethnopharmacological utilization of Wall. Ex. Benth is evident in the treatment of several types of pain and inflammation, including toothache,…”
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Preparation, Characterization and Evaluation of Flavonolignan Silymarin Effervescent Floating Matrix Tablets for Enhanced Oral Bioavailability by Ahmad, Sher, Khan, Jamshaid Ali, Kausar, Tabassum Naheed, Mahnashi, Mater H, Alasiri, Ali, Alqahtani, Abdulsalam A, Alqahtani, Thamer S, Walbi, Ismail A, Alshehri, Osama M, Elnoubi, Osman A, Mahmood, Fawad, Sadiq, Abdul

“…The convenient and highly compliant route for the delivery of active pharmaceutical ingredients is the tablet. A versatile platform of tablets is available for…”
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Vasorelaxant and Antihypertensive Effects of Bergenin on Isolated Rat Aorta and High Salt-Induced Hypertensive Rats by Ahmad, Taseer, Qayyum, Rahila, Khan, Taous, Mahnashi, Mater H., Jalal, Mohammed M., Altayar, Malik A., Alshehri, Osama M., Shah, Abdul Jabbar

“…Bergenin is a phenolic glycoside that has been reported to be present in some medicinal plants which are traditionally used for their antihypertensive actions…”
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Outcome Prediction of Hematologic Malignancy in Critically Sick People by Velmurugan, Palanivel, Moihanavel, Vinayagam, Altayar, Malik A., Jalal, Mohammed M., Kabrah, Saeed M., Qanash, Husam, Almashjary, Majed N., Alshehri, Osama M., Kunwar, Vijay Singh

“…People with hematologic malignancies (HM) frequently postulate intensive care unit (ICU) hospitalization due to organ damage caused by the disease process or…”
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Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus by Alfaifi, Mohammed, Ali Beg, Mirza Masroor, Alshahrani, Mohammed Yahya, Ahmad, Irfan, Alkhathami, Ali Gaithan, Joshi, Prakash C, Alshehri, Osama M, Alamri, Abdulrahman Manaa, Verma, Amit Kumar

“…BackgroundType 2 diabetes mellitus (T2DM) is a multifactorial disorder that leads to alterations in gene regulation. Long non-coding RNAs (lncRNAs) have become…”
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In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer’s Disease by Mahnashi, Mater H, Alshahrani, Mohammed Abdulrahman, Nahari, Mohammed H, Hassan, Syed Shams ul, Jan, Muhammad Saeed, Ayaz, Muhammad, Ullah, Farhat, Alshehri, Osama M, Alshehri, Mohammad Ali, Rashid, Umer, Sadiq, Abdul

“…Plants’ bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich dietary supplements are known to exhibit neuroprotective…”
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Evaluation of Habenaria aitchisonii Reichb. for antioxidant, anti-inflammatory, and antinociceptive effects with in vivo and in silico approaches by Asiri, Saeed Ahmed, Shabnam, Madeeha, Zafar, Rehman, Alshehri, Osama M, Alshehri, Mohammed Ali, Sadiq, Abdul, Mahnashi, Mater H, Jan, Muhammad Saeed

“…Reichb was analyzed in this research, including its chemical composition and its antioxidant, anti-inflammatory, acute oral toxicity, and antinociceptive…”
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Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands by Alshehri, Osama M, Montague, Samantha, Watson, Stephanie, Carter, Paul, Sarker, Najiat, Manne, Bhanu K, Miller, Jeanette L C, Herr, Andrew B, Pollitt, Alice Y, O'Callaghan, Chris A, Kunapuli, Satya, Arman, Mònica, Hughes, Craig E, Watson, Steve P

“…Platelets are activated by a range of stimuli that share little or no resemblance in structure to each other or to recognized ligands, including diesel exhaust…”
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Next-Gen brain tumor classification: pioneering with deep learning and fine-tuned conditional generative adversarial networks by Asiri, Abdullah A, Aamir, Muhammad, Ali, Tariq, Shaf, Ahmad, Irfan, Muhammad, Mehdar, Khlood M, Alqhtani, Samar M, Alghamdi, Ali H, Alshamrani, Abdullah Fahad A, Alshehri, Osama M

“…Brain tumor has become one of the fatal causes of death worldwide in recent years, affecting many individuals annually and resulting in loss of lives. Brain…”
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Pharmacological evaluations of amide carboxylates as potential anti-Alzheimer agents: anti-radicals, enzyme inhibition, simulation and behavioral studies in animal models by Mahnashi, Mater H., Ali, Saqib, M. Alshehri, Osama, Almazni, Ibrahim Abdullah, Asiri, Saeed Ahmed, Sadiq, Abdul, Zafar, Rehman, Jan, Muhammad Saeed

“…Alzheimer's disease (AD) is a neurological disorder that progresses gradually but irreversibly leading to dementia and is difficult to prevent and treat. There…”
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Isolation, invitro, invivo anti-inflammatory, analgesic and antioxidant potential of Habenaria plantegania Lindl by Alshehri, Osama M., Shabnam, Madeeha, Asiri, Saeed Ahmed, Mahnashi, Mater H., Sadiq, Abdul, Jan, Muhammad Saeed

“…Habenaira plantaginea belong to orchid family which is native to Asia. Members of this family are commonly famous for the cure of pain and inflammation. To…”
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Succinimide Derivatives as Antioxidant Anticholinesterases, Anti-α-Amylase, and Anti-α-Glucosidase: In Vitro and In Silico Approaches by Alshehri, Osama M., Mahnashi, Mater H., Sadiq, Abdul, Zafar, Rehman, Jan, Muhammad Saeed, Ullah, Farhat, Alshehri, Mohammed Ali, Alshamrani, Saleh, Hassan, Elhashimi E.

“…Based on the diverse pharmacological potency and the structural features of succinimide, this research considered to synthesize succinimide derivatives…”
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Multi-Level Deep Generative Adversarial Networks for Brain Tumor Classification on Magnetic Resonance Images by A. Asiri, Abdullah, Shaf, Ahmad, Ali, Tariq, Aamir, Muhammad, Usman, Ali, Irfan, Muhammad, A. Alshamrani, Hassan, M. Mehdar, Khlood, M. Alshehri, Osama, M. Alqhtani, Samar

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Phytochemical Analysis, Total Phenolic, Flavonoid Contents, and Anticancer Evaluations of Solvent Extracts and Saponins of H. digitata by Alshehri, Osama M., Alshamrani, Saleh, Mahnashi, Mater H., Alshahrani, Mohammed Merae, Khan, Jalwa Ali, Shah, Muhammad, Alshehri, Mohammed Ali, Zafar, Rehman, Zahoor, Muhammad, Jan, Muhammad Saeed, Hassan, Syed Shams ul, Sadiq, Abdul

“…Cancer is one of the most challenging diseases in the modern era for the researchers and investigators. Extensive research worldwide is underway to find novel…”
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Pneumocystis Jirovecii detection and comparison of multiple diagnostic methods with quantitative real-time PCR in patients with respiratory symptoms by Alshahrani, Mohammad Y., Alfaifi, Mohammed, Ahmad, Irfan, Alkhathami, Ali Gaithan, Hakami, Abdulrahim Refdan, Ahmad, Hafiz, Alshehri, Osama M., Dhakad, Megh Singh

“…Pneumocystis jirovecii (PCP) remains a significant cause of mortality and morbidity in patients with respiratory infections. Accurate diagnosis of PCP is still…”
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Role of miRNA-495 and NRXN-1 and CNTN-1 mRNA Expression and Its Prognostic Importance in Breast Cancer Patients by Alkhathami, Ali G., Verma, Amit Kumar, Alfaifi, Mohammed, Kumar, Lalit, Alshahrani, Mohammad Yahya, Hakami, Abdulrahim R., Alshehri, Osama M., Asiri, Mohammed, Ali Beg, Mirza Masroor

“…Breast cancer is a heterogeneous disease in which genetic factors are involved in disease worsening and higher mortality. Epidemiological and clinical research…”
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Phytochemical screening of Bixa orellana and preliminary antidiabetic, antibacterial, antifibrinolytic, anthelmintic, antioxidant, and cytotoxic activity against lung cancer (A549) cell lines by Muddapur, Uday M., Turakani, Bhagya, Jalal, Naif A., Ashgar, Sami S., Momenah, Aiman M., Alshehri, Osama M., Mahnashi, Mater H., Shaikh, Ibrahim Ahmed, Khan, Aejaz Abdullatif, Dafalla, Salah Eldeen, Malpani, Jay, Manjunath, Samiksha, Begum, Touseef, Khuwaja, Gulrana, Shakeel Iqubal, S.M.

“…[Display omitted] Bixa orellana (B. Orellana) is a frequently utilized plant that has grown in significance in pharmaceutical applications. The leaves extract…”
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