Search Results - "Alshawaf, Eman"
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iPhoneography as Visual Literacy: How Image-Making Practices on Social Media Encourage Creative Growth
Published in TechTrends (01-09-2021)“…iPhoneography is the practice of capturing, enhancing, and sharing images using a smartphone device. With the emergence of image-based social media platforms…”
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Higher binding affinity of furin for SARS-CoV-2 spike (S) protein D614G mutant could be associated with higher SARS-CoV-2 infectivity
Published in International journal of infectious diseases (01-02-2021)“…•The G clade 23403A>G mutation on the spike glycoprotein (S protein) encodes a virulent strain of SARS-CoV-2.•The D614G substitution causes the loss of a…”
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Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy
Published in International journal of molecular sciences (01-09-2023)“…Diabetic nephropathy (DN) is a complicated condition related to type 2 diabetes mellitus (T2D). ANGPTL8 is a hepatic protein highlighted as a risk factor for…”
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Targeting SARS-CoV-2 Macrodomain-1 to Restore the Innate Immune Response Using In Silico Screening of Medicinal Compounds and Free Energy Calculation Approaches
Published in Viruses (01-09-2023)“…Among the different drug targets of SARS-CoV-2, a multi-domain protein known as NSP3 is a critical element of the translational and replication machinery. The…”
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Molecular Simulation-Based Investigation of Highly Potent Natural Products to Abrogate Formation of the nsp10-nsp16 Complex of SARS-CoV-2
Published in Biomolecules (Basel, Switzerland) (14-04-2021)“…The SARS-CoV-2 non-structural protein (nsp) nsp10-nsp16 complex is essential for the 2'-O-methylation of viral mRNA, a crucial step for evading the innate…”
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Association Between Factors Involved in Bone Remodeling (Osteoactivin and OPG) With Plasma Levels of Irisin and Meteorin-Like Protein in People With T2D and Obesity
Published in Frontiers in endocrinology (Lausanne) (29-10-2021)“…The musculoskeletal system consisting of bones and muscles have been recognized as endocrine organs secreting hormones that are involved in regulating…”
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Exploring the Binding Mechanism of NRG1–ERBB3 Complex and Discovery of Potent Natural Products to Reduce Diabetes-Assisted Breast Cancer Progression
Published in Interdisciplinary sciences : computational life sciences (01-09-2023)“…Diabetes mellitus significantly contributes to breast cancer progression, where hyperglycemia upregulates specific genes, leading to more aggressive tumor…”
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Association of significantly elevated plasma levels of NGAL and IGFBP4 in patients with diabetic nephropathy
Published in BMC nephrology (11-02-2022)“…Diabetic nephropathy (DN) is a type of progressive kidney disease affecting approximately 40% of patients with diabetes. Current DN diagnostic criteria…”
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Angiopoietin-2 and Angiopoietin-like Proteins with a Prospective Role in Predicting Diabetic Nephropathy
Published in Biomedicines (01-05-2024)“…Angiopoietins are crucial growth factors for maintaining a healthy, functional endothelium. Patients with type 2 diabetes (T2D) exhibit significant levels of…”
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Structural-Dynamics and Binding Analysis of RBD from SARS-CoV-2 Variants of Concern (VOCs) and GRP78 Receptor Revealed Basis for Higher Infectivity
Published in Microorganisms (Basel) (11-11-2021)“…Glucose-regulated protein 78 (GRP78) might be a receptor for SARS-CoV-2 to bind and enter the host cell. Recently reported mutations in the spike glycoprotein…”
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Structural analysis of ACE2 variant N720D demonstrates a higher binding affinity to TMPRSS2
Published in Life sciences (1973) (15-10-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel member of the betacoronaviruses family affecting the lower respiratory tract mainly…”
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Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approach
Published in Microbial pathogenesis (01-09-2022)“…Neuropilin-1 (NRP1) is a widely expressed cell surface receptor protein characterized by its pleiotropic function. Recent reports highlighted NRP1 as an…”
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